Module 551 Residual: 0.63

Title Bicluster Model Residual Score
bicluster_0551 v02 0.63 -6.37
Displaying 1 - 16 of 16
Rv0198c Metallopeptidase

Details for Rv0198c - Metallopeptidase

GO Terms: GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0198c

Tuberculist Genomic Region

Rv0633c Possible membrane protein

Details for Rv0633c - Possible membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0633c

Tuberculist Genomic Region

Rv0993 UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9)

Details for Rv0993 - UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9)

GO Terms: GO:0003983, GO:0003983, GO:0005886, GO:0040007

PATRIC Pathways: Amino sugar and nucleotide sugar metabolism, Starch and sucrose metabolism, Pentose and glucuronate interconversions, Galactose metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.10 | In vivo Essential: NA

Go to Gene Page: Rv0993

Tuberculist Genomic Region

Rv1271c

Details for Rv1271c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1271c

Tuberculist Genomic Region

Rv2190c Probable endopeptidase

Details for Rv2190c - Probable endopeptidase

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.04 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2190c

Tuberculist Genomic Region

Rv2427c Gamma-glutamyl phosphate reductase (EC 1.2.1.41)

Details for Rv2427c - Gamma-glutamyl phosphate reductase (EC 1.2.1.41)

GO Terms: GO:0004350, GO:0005829, GO:0005886

PATRIC Pathways: Arginine and proline metabolism

Essentiality: Griffin Essential: 0.64 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2427c

Tuberculist Genomic Region

Rv2477c ABC transporter ATP-binding protein

Details for Rv2477c - ABC transporter ATP-binding protein

GO Terms: GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv2477c

Tuberculist Genomic Region

Rv2536 Possible membrane protein

Details for Rv2536 - Possible membrane protein

GO Terms: GO:0005887, GO:0046812

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2536

Tuberculist Genomic Region

Rv2982c Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94)

Details for Rv2982c - Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94)

GO Terms: GO:0047952, GO:0005886

PATRIC Pathways: Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2982c

Tuberculist Genomic Region

Rv3116 Sulfur carrier protein adenylyltransferase ThiF

Details for Rv3116 - Sulfur carrier protein adenylyltransferase ThiF

GO Terms: GO:0003824

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3116

Tuberculist Genomic Region

Rv3274c Butyryl-CoA dehydrogenase (EC 1.3.99.2)

Details for Rv3274c - Butyryl-CoA dehydrogenase (EC 1.3.99.2)

GO Terms: GO:0004085, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3274c

Tuberculist Genomic Region

Rv3285 Biotin carboxylase of acetyl-CoA carboxylase (EC 6.3.4.14) / Biotin carboxyl carrier protein of acetyl-CoA carboxylase

Details for Rv3285 - Biotin carboxylase of acetyl-CoA carboxylase (EC 6.3.4.14) / Biotin carboxyl carrier protein of acetyl-CoA carboxylase

GO Terms: GO:0003989, GO:0005515, GO:0005886, GO:0009317, GO:0040007

PATRIC Pathways: Fatty acid biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv3285

Tuberculist Genomic Region

Rv3311

Details for Rv3311 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.66 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3311

Tuberculist Genomic Region

Rv3389c Enoyl-CoA hydratase

Details for Rv3389c - Enoyl-CoA hydratase

GO Terms: GO:0005829, GO:0005886, GO:0006633, GO:0016508, GO:0019171

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3389c

Tuberculist Genomic Region

Rv3682 Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

Details for Rv3682 - Multimodular transpeptidase-transglycosylase (EC 2.4.1.129) (EC 3.4.-.-)

GO Terms: GO:0008955, GO:0005829, GO:0005886

PATRIC Pathways: Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.45 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3682

Tuberculist Genomic Region

Rv3850

Details for Rv3850 -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3850

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 390 e-value: 4300
Displaying 1 - 1 of 1
response regulator
regulates 69 modules
Weight: 
0.18
up-regulates
Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR
regulates 90 modules
Weight: 
0.15
up-regulates
POSSIBLE HISTONE-LIKE PROTEIN HNS
regulates 12 modules
Weight: 
0.14
up-regulates
HspR, transcriptional repressor of DnaK operon
regulates 13 modules
Weight: 
0.11
up-regulates
Transcriptional regulator, TetR family
regulates 23 modules
Weight: 
0.09
up-regulates
Single-stranded DNA-binding protein
regulates 26 modules
Weight: 
0.09
up-regulates
regulates 26 modules
Weight: 
0.09
up-regulates
regulates 22 modules
Weight: 
0.08
up-regulates
Transcriptional regulator, TetR family
regulates 54 modules
Weight: 
0.05
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 20 of 20
GO:0005618 |

cell wall

GO:0005886 |

plasma membrane

GO:0003983 |

UTP:glucose-1-phosphate uridylyltransferase activity

GO:0040007 |

growth

GO:0005576 |

extracellular region

GO:0004350 |

glutamate-5-semialdehyde dehydrogenase activity

GO:0005829 |

cytosol

GO:0005887 |

integral to plasma membrane

GO:0046812 |

host cell surface binding

GO:0047952 |

glycerol-3-phosphate dehydrogenase [NAD(P)+] activity

GO:0003824 |

catalytic activity

GO:0004085 |

butyryl-CoA dehydrogenase activity

GO:0003989 |

acetyl-CoA carboxylase activity

GO:0005515 |

protein binding

GO:0009317 |

acetyl-CoA carboxylase complex

GO:0006633 |

fatty acid biosynthetic process

GO:0016508 |

long-chain-enoyl-CoA hydratase activity

GO:0019171 |

3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity

GO:0008955 |

peptidoglycan glycosyltransferase activity