Module 581 Residual: 0.61

Title Bicluster Model Residual Score
bicluster_0581 v02 0.61 -11.06
Displaying 1 - 19 of 19
Rv2326c Candidate substrate-specific domain of ECF transporters in Mycobacteria / Duplicated ATPase component of energizing module of predicted ECF transporter in Mycobacteria

Details for Rv2326c - Candidate substrate-specific domain of ECF transporters in Mycobacteria / Duplicated ATPase component of energizing module of predicted ECF transporter in Mycobacteria

GO Terms: GO:0005524, GO:0016887, GO:0005886, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2326c

Tuberculist Genomic Region

Rv2916c Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1)

Details for Rv2916c - Signal recognition particle, subunit Ffh SRP54 (TC 3.A.5.1.1)

GO Terms: GO:0003723, GO:0006605, GO:0016020, GO:0006614, GO:0005525, GO:0005618, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv2916c

Tuberculist Genomic Region

Rv0204c Possible membrane protein

Details for Rv0204c - Possible membrane protein

GO Terms: GO:0005618, GO:0005886, GO:0044119

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: 0.35

Go to Gene Page: Rv0204c

Tuberculist Genomic Region

Rv0505c Phosphoserine phosphatase (EC 3.1.3.3)

Details for Rv0505c - Phosphoserine phosphatase (EC 3.1.3.3)

GO Terms: GO:0005886, GO:0005887

PATRIC Pathways: Methane metabolism, Glycine, serine and threonine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0505c

Tuberculist Genomic Region

Rv0509 Glutamyl-tRNA reductase (EC 1.2.1.70)

Details for Rv0509 - Glutamyl-tRNA reductase (EC 1.2.1.70)

GO Terms: GO:0008883, GO:0040007

PATRIC Pathways: Porphyrin and chlorophyll metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv0509

Tuberculist Genomic Region

Rv0510 Porphobilinogen deaminase (EC 2.5.1.61)

Details for Rv0510 - Porphobilinogen deaminase (EC 2.5.1.61)

GO Terms: GO:0004418, GO:0005886, GO:0040007

PATRIC Pathways: Porphyrin and chlorophyll metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv0510

Tuberculist Genomic Region

Rv0511 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)

Details for Rv0511 - Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Porphyrin and chlorophyll metabolism, Porphyrin and chlorophyll metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv0511

Tuberculist Genomic Region

Rv0512 Porphobilinogen synthase (EC 4.2.1.24)

Details for Rv0512 - Porphobilinogen synthase (EC 4.2.1.24)

GO Terms: GO:0004655

PATRIC Pathways: Porphyrin and chlorophyll metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0512

Tuberculist Genomic Region

Rv0513 Transmembrane transport protein MmpL2

Details for Rv0513 - Transmembrane transport protein MmpL2

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.59 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0513

Tuberculist Genomic Region

Rv0514 Possible membrane protein

Details for Rv0514 - Possible membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.39 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0514

Tuberculist Genomic Region

Rv0994 Molybdopterin biosynthesis protein MoeA

Details for Rv0994 - Molybdopterin biosynthesis protein MoeA

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0994

Tuberculist Genomic Region

Rv1093 Serine hydroxymethyltransferase 1 (EC 2.1.2.1)

Details for Rv1093 - Serine hydroxymethyltransferase 1 (EC 2.1.2.1)

GO Terms: GO:0004372, GO:0004372, GO:0005886, GO:0006544, GO:0006563, GO:0030170, GO:0042783, GO:0042803

PATRIC Pathways: Cyanoamino acid metabolism, Glycine, serine and threonine metabolism, One carbon pool by folate, Methane metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1093

Tuberculist Genomic Region

Rv2697c Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23)

Details for Rv2697c - Deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23)

GO Terms: GO:0004170, GO:0000287, GO:0004170, GO:0040007, GO:0046080

PATRIC Pathways: Pyrimidine metabolism

Essentiality: Griffin Essential: 0.08 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv2697c

Tuberculist Genomic Region

Rv2698 PROBABLE CONSERVED ALANINE RICH TRANSMEMBRANE PROTEIN

Details for Rv2698 - PROBABLE CONSERVED ALANINE RICH TRANSMEMBRANE PROTEIN

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.13 | In vivo Essential: NA

Go to Gene Page: Rv2698

Tuberculist Genomic Region

Rv2781c 2-nitropropane dioxygenase (EC 1.13.11.32)

Details for Rv2781c - 2-nitropropane dioxygenase (EC 1.13.11.32)

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.27 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2781c

Tuberculist Genomic Region

Rv3275c Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)

Details for Rv3275c - Phosphoribosylaminoimidazole carboxylase catalytic subunit (EC 4.1.1.21)

GO Terms: GO:0004638, GO:0040007

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.05 | In vitro Essential: 0.14 | In vivo Essential: NA

Go to Gene Page: Rv3275c

Tuberculist Genomic Region

Rv3276c Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)

Details for Rv3276c - Phosphoribosylaminoimidazole carboxylase ATPase subunit (EC 4.1.1.21)

GO Terms: GO:0004638, GO:0005886

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3276c

Tuberculist Genomic Region

Rv3328c putative RNA polymerase sigma factor

Details for Rv3328c - putative RNA polymerase sigma factor

GO Terms: GO:0042542

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3328c

Tuberculist Genomic Region

Rv3835 PROBABLE CONSERVED MEMBRANE PROTEIN

Details for Rv3835 - PROBABLE CONSERVED MEMBRANE PROTEIN

GO Terms: GO:0005576, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.40 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3835

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.0065 e-value: 120
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 29 of 29
GO:0005524 |

ATP binding

GO:0016887 |

ATPase activity

GO:0005886 |

plasma membrane

GO:0005887 |

integral to plasma membrane

GO:0003723 |

RNA binding

GO:0006605 |

protein targeting

GO:0016020 |

membrane

GO:0006614 |

SRP-dependent cotranslational protein targeting to membrane

GO:0005525 |

GTP binding

GO:0005618 |

cell wall

GO:0040007 |

growth

GO:0044119 |

growth of symbiont in host cell

GO:0008883 |

glutamyl-tRNA reductase activity

GO:0004418 |

hydroxymethylbilane synthase activity

GO:0004655 |

porphobilinogen synthase activity

GO:0005829 |

cytosol

GO:0004372 |

glycine hydroxymethyltransferase activity

GO:0006544 |

glycine metabolic process

GO:0006563 |

L-serine metabolic process

GO:0030170 |

pyridoxal phosphate binding

GO:0042783 |

active evasion of host immune response

GO:0042803 |

protein homodimerization activity

GO:0004170 |

dUTP diphosphatase activity

GO:0000287 |

magnesium ion binding

GO:0046080 |

dUTP metabolic process

GO:0004638 |

phosphoribosylaminoimidazole carboxylase activity

GO:0042542 |

response to hydrogen peroxide

GO:0005576 |

extracellular region