Module 582 Residual: 0.57

Title Bicluster Model Residual Score
bicluster_0582 v02 0.57 -11.33
Displaying 1 - 19 of 19
Rv0423c Hydroxymethylpyrimidine phosphate synthase ThiC

Details for Rv0423c - Hydroxymethylpyrimidine phosphate synthase ThiC

GO Terms: GO:0009228, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv0423c

Tuberculist Genomic Region

Rv0490 Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3); Sensor-like histidine kinase senX3 (EC 2.7.13.3)

Details for Rv0490 - Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3); Sensor-like histidine kinase senX3 (EC 2.7.13.3)

GO Terms: GO:0008150, GO:0005576, GO:0009405, GO:0018106, GO:0046777

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.40 | In vitro Essential: NA | In vivo Essential: 0.21

Go to Gene Page: Rv0490

Tuberculist Genomic Region

Rv1410c EmrB/QacA family drug resistance transporter

Details for Rv1410c - EmrB/QacA family drug resistance transporter

GO Terms: GO:0005887, GO:0008144, GO:0009405, GO:0015562

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.11 | In vitro Essential: NA | In vivo Essential: 0.04

Go to Gene Page: Rv1410c

Tuberculist Genomic Region

Rv1411c Lipoprotein LprG

Details for Rv1411c - Lipoprotein LprG

GO Terms: GO:0005886, GO:0009405

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: 0.10

Go to Gene Page: Rv1411c

Tuberculist Genomic Region

Rv1412 Riboflavin synthase eubacterial/eukaryotic (EC 2.5.1.9)

Details for Rv1412 - Riboflavin synthase eubacterial/eukaryotic (EC 2.5.1.9)

GO Terms: GO:0004746

PATRIC Pathways: Riboflavin metabolism

Essentiality: Griffin Essential: 0.05 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1412

Tuberculist Genomic Region

Rv1487 Putative activity regulator of membrane protease YbbK

Details for Rv1487 - Putative activity regulator of membrane protease YbbK

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.40 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1487

Tuberculist Genomic Region

Rv1488 Putative stomatin/prohibitin-family membrane protease subunit YbbK

Details for Rv1488 - Putative stomatin/prohibitin-family membrane protease subunit YbbK

GO Terms: GO:0005576, GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1488

Tuberculist Genomic Region

Rv1795 Type VII secretion integral membrane protein EccD

Details for Rv1795 - Type VII secretion integral membrane protein EccD

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.05 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1795

Tuberculist Genomic Region

Rv1797 Type VII secretion protein EccE

Details for Rv1797 - Type VII secretion protein EccE

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.03 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1797

Tuberculist Genomic Region

Rv1798 Type VII secretion AAA-ATPase EccA

Details for Rv1798 - Type VII secretion AAA-ATPase EccA

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.22 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1798

Tuberculist Genomic Region

Rv1843c Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)

Details for Rv1843c - Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)

GO Terms: GO:0003938, GO:0005829, GO:0005886

PATRIC Pathways: Purine metabolism, Drug metabolism - other enzymes

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1843c

Tuberculist Genomic Region

Rv2202c Adenosine kinase (EC 2.7.1.20)

Details for Rv2202c - Adenosine kinase (EC 2.7.1.20)

GO Terms: GO:0000287, GO:0004001, GO:0005524, GO:0005525, GO:0005886, GO:0032567, GO:0042803

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2202c

Tuberculist Genomic Region

Rv2535c Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific)

Details for Rv2535c - Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific)

GO Terms: GO:0008235, GO:0006508

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.08 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2535c

Tuberculist Genomic Region

Rv2868c 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase (EC 1.17.7.1)

Details for Rv2868c - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase (EC 1.17.7.1)

GO Terms: GO:0046429, GO:0005886

PATRIC Pathways: Terpenoid backbone biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2868c

Tuberculist Genomic Region

Rv2941 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv2941 - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0004467, GO:0004321, GO:0005886, GO:0008610, GO:0044119, GO:0052572, GO:0070566, GO:0071766, GO:0071770

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.77 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2941

Tuberculist Genomic Region

Rv2942 Putative membrane protein MmpL7

Details for Rv2942 - Putative membrane protein MmpL7

GO Terms: GO:0005887, GO:0006855, GO:0006869, GO:0044119, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.93 | In vitro Essential: NA | In vivo Essential: 0.26

Go to Gene Page: Rv2942

Tuberculist Genomic Region

Rv3596c ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence clcC/mecB

Details for Rv3596c - ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence clcC/mecB

GO Terms: GO:0006289, GO:0005515, GO:0004518, GO:0019538, GO:0003677, GO:0005524, GO:0005515, GO:0005829, GO:0005886, GO:0016887, GO:0040007, GO:0042803, GO:0044183

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.18 | In vivo Essential: NA

Go to Gene Page: Rv3596c

Tuberculist Genomic Region

Rv3813c Cof family hydrolase

Details for Rv3813c - Cof family hydrolase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.80 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3813c

Tuberculist Genomic Region

Rv3815c 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

Details for Rv3815c - 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

GO Terms: GO:0003841

PATRIC Pathways: Glycerolipid metabolism, Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3815c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.07 e-value: 0.22
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 43 of 43
GO:0009228 |

thiamine biosynthetic process

GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0040007 |

growth

GO:0008150 |

biological_process

GO:0005576 |

extracellular region

GO:0009405 |

pathogenesis

GO:0018106 |

peptidyl-histidine phosphorylation

GO:0046777 |

protein autophosphorylation

GO:0005887 |

integral to plasma membrane

GO:0008144 |

drug binding

GO:0015562 |

efflux transmembrane transporter activity

GO:0004746 |

riboflavin synthase activity

GO:0005618 |

cell wall

GO:0003938 |

IMP dehydrogenase activity

GO:0000287 |

magnesium ion binding

GO:0004001 |

adenosine kinase activity

GO:0005524 |

ATP binding

GO:0005525 |

GTP binding

GO:0032567 |

dGTP binding

GO:0042803 |

protein homodimerization activity

GO:0008235 |

metalloexopeptidase activity

GO:0006508 |

proteolysis

GO:0046429 |

4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity

GO:0004467 |

long-chain fatty acid-CoA ligase activity

GO:0004321 |

fatty-acyl-CoA synthase activity

GO:0008610 |

lipid biosynthetic process

GO:0044119 |

growth of symbiont in host cell

GO:0052572 |

response to host immune response

GO:0070566 |

adenylyltransferase activity

GO:0071766 |

Actinobacterium-type cell wall biogenesis

GO:0071770 |

DIM/DIP cell wall layer assembly

GO:0006855 |

drug transmembrane transport

GO:0006869 |

lipid transport

GO:0006289 |

nucleotide-excision repair

GO:0005515 |

protein binding

GO:0004518 |

nuclease activity

GO:0019538 |

protein metabolic process

GO:0003677 |

DNA binding

GO:0016887 |

ATPase activity

GO:0044183 |

protein binding involved in protein folding

GO:0003841 |

1-acylglycerol-3-phosphate O-acyltransferase activity