Rv0023 Transcriptional regulatory protein

Rv0023 (Transcriptional regulatory protein) is predicted to be co-regulated in modules bicluster_0304 with residual 0.58 and bicluster_0544 with residual 0.41.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.36 and 78.00 for bicluster_0304 and 420.00 and 780.00 for bicluster_0544 respectively.

These modules are enriched for following go terms: cellular ketone metabolic process cellular homeostasis, homeostatic process, regulation of biological quality, electron carrier activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 31 - 40 of 174
Gene Target Differential Expression Distance Expression pvalue Type
Possible membrane protein
No -50 0.43 0.00077106 Primary.TSS
Programmed cell death toxin YdcE
Repressed 48 -1.41 0.0000012 Primary.TSS
No results were found NA 48 Internal.TSS
POSSIBLE MYCOLIC ACID SYNTHASE UMAA1
No 16 0.36 0.105456 Primary.TSS
Iron-regulated heparin binding hemagglutinin HbhA (Adhesin)
No -42 0.46 0.00437794 CDS
Repressed 13 -1.12 0.00141562 Primary.TSS
DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6)
Repressed -35 -0.89 0.0000018 CDS
Translation elongation factor Tu
No 6 -0.05 0.869091 Primary.TSS
Mycofactocin system transcriptional regulator
Induced 67 0.85 0.000384364 CDS
Mycofactocin system small protein
No 20 0.49 0.0624558 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.35 U
D3I 3 3 3.83 11.63 I
D3U 3 3 3.83 11.40 U
D5I 9 5 6.00 12.32 I
D5U 17 5 6.00 12.61 U
D7I 18 7 8.14 8.45 I
D7U 19 7 8.14 11.60 U
D14I 4 14 15.63 6.26 I
D14U 4 14 15.63 9.95 U
D17I 3 17 19.15 5.13 I
D17U 3 17 19.15 9.94 U
D21I 4 21 23.23 5.32 I
D21U 4 21 23.23 9.06 U
D24I 3 24 26.60 4.70 I
D24U 3 24 26.60 9.32 U
D28I 4 28 30.61 5.55 I
D28U 4 28 30.61 8.40 U