Rv0023 Transcriptional regulatory protein

Rv0023 (Transcriptional regulatory protein) is predicted to be co-regulated in modules bicluster_0304 with residual 0.58 and bicluster_0544 with residual 0.41.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.36 and 78.00 for bicluster_0304 and 420.00 and 780.00 for bicluster_0544 respectively.

These modules are enriched for following go terms: cellular ketone metabolic process cellular homeostasis, homeostatic process, regulation of biological quality, electron carrier activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 61 - 70 of 174
Gene Target Differential Expression Distance Expression pvalue Type
Lysine decarboxylase family
No 1 -0.35 0.0995841 Antisense.TSS
RNA polymerase sigma-70 factor, ECF subfamily
Induced 29 0.88 0.00101763 Primary.TSS
POSSIBLE MEMBRANE PROTEIN
Repressed -32 -1.83 3.34e-19 Primary.TSS
PE-PGRS FAMILY PROTEIN
No -15 -0.06 0.872052 Primary.TSS
1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18)
Repressed -15 -0.62 0.000234941 Internal.TSS
Metal-dependent hydrolases of the beta-lactamase superfamily III
Repressed -8 -0.61 0.0000229 CDS
Metal-dependent hydrolases of the beta-lactamase superfamily III
Repressed -59 -0.61 0.0000229 Internal.TSS
S-adenosylmethionine synthetase (EC 2.5.1.6)
No 13 -0.2 0.0899812 Primary.TSS
\Probable conserved Proline, Glycine, Valine-rich secreted protein\\\""
No -48 -0.04 0.897037 Primary.TSS
Repressed 12 -1.4 0.000741646 Internal.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.35 U
D3I 3 3 3.83 11.63 I
D3U 3 3 3.83 11.40 U
D5I 9 5 6.00 12.32 I
D5U 17 5 6.00 12.61 U
D7I 18 7 8.14 8.45 I
D7U 19 7 8.14 11.60 U
D14I 4 14 15.63 6.26 I
D14U 4 14 15.63 9.95 U
D17I 3 17 19.15 5.13 I
D17U 3 17 19.15 9.94 U
D21I 4 21 23.23 5.32 I
D21U 4 21 23.23 9.06 U
D24I 3 24 26.60 4.70 I
D24U 3 24 26.60 9.32 U
D28I 4 28 30.61 5.55 I
D28U 4 28 30.61 8.40 U