Rv0023 Transcriptional regulatory protein

Rv0023 (Transcriptional regulatory protein) is predicted to be co-regulated in modules bicluster_0304 with residual 0.58 and bicluster_0544 with residual 0.41.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.36 and 78.00 for bicluster_0304 and 420.00 and 780.00 for bicluster_0544 respectively.

These modules are enriched for following go terms: cellular ketone metabolic process cellular homeostasis, homeostatic process, regulation of biological quality, electron carrier activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 41 - 50 of 174
Gene Target Differential Expression Distance Expression pvalue Type
LSU ribosomal protein L15p (L27Ae)
No -64 -0.17 0.4892 Internal.TSS
Possible protease IV SppA (endopeptidase IV) (signal peptide peptidase)
No -64 -0.25 0.0328179 Primary.TSS
Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
No -66 0.09 0.790477 CDS
PE family protein
Induced 39 0.74 0.0125839 Primary.TSS
PROBABLE INTEGRAL MEMBRANE PROTEIN
Repressed -55 -1.72 5.33e-18 Internal.TSS
PROBABLE INTEGRAL MEMBRANE PROTEIN
Repressed -49 -1.72 5.33e-18 CDS
Transcriptional regulator, TetR family
No -29 0.21 0.198458 Primary.TSS
No -25 0.21 0.633486 Internal.TSS
No 14 0.21 0.633486 CDS
Induced -129 1.41 0.0000000000467 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.35 U
D3I 3 3 3.83 11.63 I
D3U 3 3 3.83 11.40 U
D5I 9 5 6.00 12.32 I
D5U 17 5 6.00 12.61 U
D7I 18 7 8.14 8.45 I
D7U 19 7 8.14 11.60 U
D14I 4 14 15.63 6.26 I
D14U 4 14 15.63 9.95 U
D17I 3 17 19.15 5.13 I
D17U 3 17 19.15 9.94 U
D21I 4 21 23.23 5.32 I
D21U 4 21 23.23 9.06 U
D24I 3 24 26.60 4.70 I
D24U 3 24 26.60 9.32 U
D28I 4 28 30.61 5.55 I
D28U 4 28 30.61 8.40 U