Rv1776c Transcriptional regulator, TetR family

Rv1776c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0160 with residual 0.59 and bicluster_0332 with residual 0.53.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 5,000.00 for bicluster_0160 and 0.02 and 590.00 for bicluster_0332 respectively.

These modules are enriched for following go terms: purine nucleotide biosynthetic process, purine nucleotide metabolic process, purine-containing compound biosynthetic ....

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 11 - 20 of 29
Gene Target Differential Expression Distance Expression pvalue Type
Dihydroflavonol-4-reductase (EC 1.1.1.219)
No -49 -0.01 0.985104 Antisense.TSS
Alcohol dehydrogenase (EC 1.1.1.1)
No -92 0.13 0.785745 Primary.TSS
MCE-family protein Mce1C
No 63 -0.6 0.203245 Antisense.TSS
Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32)
Repressed 4 -0.66 0.0360056 Primary.TSS
Esterase LipC
No -12 -0.18 0.33248 Primary.TSS
Aldehyde dehydrogenase (EC 1.2.1.3)
No 50 0.12 0.809492 Antisense.TSS
Aldehyde dehydrogenase (EC 1.2.1.3)
No -12 0.12 0.809492 CDS
Heat shock protein hsp
No 17 0.06 0.945101 CDS
ATP-dependent DNA ligase (EC 6.5.1.1)
No 44 -0.43 0.0591207 CDS
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
No 8 -0.34 0.109719 Primary.TSS
not assigned to any KEGG Pathway.
GO:0005886

plasma membrane

plasma membrane

Details: 
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO Category: 
cellular_component
1284
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.32 U
D3I 3 3 3.83 10.57 I
D3U 3 3 3.83 10.99 U
D5I 9 5 6.00 7.59 I
D5U 17 5 6.00 9.96 U
D7I 18 7 8.14 7.88 I
D7U 19 7 8.14 11.07 U
D14I 4 14 15.63 2.57 I
D14U 4 14 15.63 9.96 U
D17I 3 17 19.15 I
D17U 3 17 19.15 9.94 U
D21I 4 21 23.23 2.50 I
D21U 4 21 23.23 8.61 U
D24I 3 24 26.60 1.96 I
D24U 3 24 26.60 8.97 U
D28I 4 28 30.61 1.56 I
D28U 4 28 30.61 7.65 U