Rv2071c Cobalt-precorrin-4 C11-methyltransferase (EC 188.8.131.52)
This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.02 for bicluster_0057 and 310.00 and 800.00 for bicluster_0497 respectively.
These modules are enriched for following go terms: tetrapyrrole metabolic process, tetrapyrrole biosynthetic process, vitamin metabolic process, water-soluble vitamin metabolic process, vitamin biosynthetic process, water-soluble vitamin biosynthetic proce... 3-hydroxyacyl-CoA dehydrogenase activity.
This gene is found to be for growth on cholesterol.
Mutant available?: Yes
|Product (LegacyBRC)||Product (RefSeq)|
|Precorrin-4 C-methyltransferase||precorrin-4 C11-methyltransferase CobM|
|BioCyc Gene Page||Cellular Overview Map|
reports the log2 abundance fold change of each TFI strain, relative to no induction, in absence or presence of drug, averaged across experimental replicates. Also reported are the accompanying z-scores and two-sided t-test p-values for each TFI strain under each condition. Please refer to Ma et al., 2020, Nature Microbiology for more information.