Rv3249c Transcriptional regulator, TetR family

Rv3249c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0063 with residual 0.56 and bicluster_0167 with residual 0.51.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 37.00 for bicluster_0063 and 0.00 and 49.00 for bicluster_0167 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 31 - 40 of 129
Gene Target Differential Expression Distance Expression pvalue Type
Gamma-glutamyltranspeptidase (EC 2.3.2.2)
No -16 0.13 0.619075 CDS
Methyltransferase (EC 2.1.1.-)
No -29 -0.8 0.0682593 Primary.TSS
Glyoxalase family protein
No -68 -0.24 0.499205 CDS
Molybdenum cofactor biosynthesis protein MoaB
No -15 -0.1 0.610719 Internal.TSS
Molybdopterin biosynthesis protein MoeA
No -60 0.06 0.801866 Antisense.TSS
Cystathionine gamma-lyase (EC 4.4.1.1)
No -140 0.01 0.98433 CDS
No -59 0.27 0.524336 Primary.TSS
Transcriptional regulator, XRE family
No -98 -0.33 0.608774 CDS
2-methylcitrate dehydratase (EC 4.2.1.79)
No -119 0.36 0.711307 CDS
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (EC 2.1.1.14)
No -126 -0.05 0.884712 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 13.44 U
D3I 3 3 3.83 13.39 I
D3U 3 3 3.83 13.06 U
D5I 9 5 6.00 13.87 I
D5U 17 5 6.00 13.73 U
D7I 18 7 8.14 13.67 I
D7U 19 7 8.14 13.15 U
D14I 4 14 15.63 11.79 I
D14U 4 14 15.63 11.70 U
D17I 3 17 19.15 10.81 I
D17U 3 17 19.15 10.88 U
D21I 4 21 23.23 10.36 I
D21U 4 21 23.23 11.06 U
D24I 3 24 26.60 9.00 I
D24U 3 24 26.60 9.91 U
D28I 4 28 30.61 8.76 I
D28U 4 28 30.61 10.03 U