Rv3249c Transcriptional regulator, TetR family

Rv3249c (Transcriptional regulator, TetR family) is predicted to be co-regulated in modules bicluster_0063 with residual 0.56 and bicluster_0167 with residual 0.51.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.01 and 37.00 for bicluster_0063 and 0.00 and 49.00 for bicluster_0167 respectively.

These modules are enriched for following go terms: .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 21 - 30 of 129
Gene Target Differential Expression Distance Expression pvalue Type
No -134 -0.02 0.981941 Antisense.TSS
No -69 -0.02 0.981941 CDS
No -108 -0.02 0.981941 Internal.TSS
Repressed -134 -0.7 0.0000000569 Primary.TSS
No 68 -0.06 0.938606 Primary.TSS
Translation elongation factor G
No 14 0.02 0.937398 Internal.TSS
Ferredoxin reductase
No 21 -0.1 0.739859 Internal.TSS
Ferredoxin reductase
No 33 -0.1 0.739859 CDS
LSU ribosomal protein L15p (L27Ae)
No -78 0.03 0.951129 Internal.TSS
Possible protease IV SppA (endopeptidase IV) (signal peptide peptidase)
No -78 -0.09 0.663705 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 13.44 U
D3I 3 3 3.83 13.39 I
D3U 3 3 3.83 13.06 U
D5I 9 5 6.00 13.87 I
D5U 17 5 6.00 13.73 U
D7I 18 7 8.14 13.67 I
D7U 19 7 8.14 13.15 U
D14I 4 14 15.63 11.79 I
D14U 4 14 15.63 11.70 U
D17I 3 17 19.15 10.81 I
D17U 3 17 19.15 10.88 U
D21I 4 21 23.23 10.36 I
D21U 4 21 23.23 11.06 U
D24I 3 24 26.60 9.00 I
D24U 3 24 26.60 9.91 U
D28I 4 28 30.61 8.76 I
D28U 4 28 30.61 10.03 U