Rv3574 Transcriptional regulator kstR (Rv3574), TetR family

Rv3574 (Transcriptional regulator kstR (Rv3574), TetR family) is predicted to be co-regulated in modules bicluster_0199 with residual 0.54 and bicluster_0200 with residual 0.45.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0199 and 0.00 and 0.16 for bicluster_0200 respectively.

These modules are enriched for following go terms: coenzyme binding, oxidoreductase activity.

This gene is found to be for growth on cholesterol.

Mutant available?: Yes

Displaying 131 - 138 of 138
Gene Target Differential Expression Distance Expression pvalue Type
UDP-galactopyranose mutase (EC 5.4.99.9)
No 66 -0.1 0.714869 Primary.TSS
Exported repetitive protein precursor (Cell surface protein pirG) (EXP53)
No -122 0.09 0.741041 Primary.TSS
1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)
No 42 0.04 0.882536 Antisense.TSS
1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)
No -73 0.04 0.882536 CDS
Induced 58 0.65 0.0332366 Internal.TSS
Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556)
No 58 0.12 0.729608 Primary.TSS
Mobile element protein
No -52 -0.42 0.0544581 CDS
Cell division protein FtsH (EC 3.4.24.-)
No 25 -0.08 0.707369 CDS
not assigned to any KEGG Pathway.
GO:0003677

DNA binding

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO Category: 
molecular_function
37
Total items in this category:  
GO:0042803

protein homodimerization activity

protein homodimerization activity

Details: 
Interacting selectively and non-covalently with an identical protein to form a homodimer.
GO Category: 
molecular_function
83
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.17 U
D3I 3 3 3.83 11.79 I
D3U 3 3 3.83 10.90 U
D5I 9 5 6.00 10.89 I
D5U 17 5 6.00 11.76 U
D7I 18 7 8.14 10.15 I
D7U 19 7 8.14 11.31 U
D14I 4 14 15.63 4.32 I
D14U 4 14 15.63 8.47 U
D17I 3 17 19.15 2.30 I
D17U 3 17 19.15 7.41 U
D21I 4 21 23.23 2.50 I
D21U 4 21 23.23 7.03 U
D24I 3 24 26.60 I
D24U 3 24 26.60 5.82 U
D28I 4 28 30.61 I
D28U 4 28 30.61 5.94 U