Rv3574 Transcriptional regulator kstR (Rv3574), TetR family

Rv3574 (Transcriptional regulator kstR (Rv3574), TetR family) is predicted to be co-regulated in modules bicluster_0199 with residual 0.54 and bicluster_0200 with residual 0.45.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0199 and 0.00 and 0.16 for bicluster_0200 respectively.

These modules are enriched for following go terms: coenzyme binding, oxidoreductase activity.

This gene is found to be for growth on cholesterol.

Mutant available?: Yes

Displaying 111 - 120 of 138
Gene Target Differential Expression Distance Expression pvalue Type
FadE30
Repressed -111 -0.61 0.0112002 CDS
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
Repressed -6 -1.08 0.000167065 CDS
Enoyl-CoA hydratase (EC 4.2.1.17)
Repressed -35 -1.07 0.00000795 Primary.TSS
Repressed -132 -1.97 2.09e-24 CDS
PPE family protein
No -127 0.17 0.252292 Primary.TSS
2-keto-4-pentenoate hydratase (EC 4.2.1.-)
Repressed -92 -1.22 0.00000000000000159 Primary.TSS
3-oxosteroid 1-dehydrogenase (EC 1.3.99.4)
Repressed -92 -1.35 0.000000275 Antisense.TSS
3-oxosteroid 1-dehydrogenase (EC 1.3.99.4)
Repressed -9 -1.35 0.000000275 CDS
POSSIBLE OXIDOREDUCTASE
Repressed 45 -3.73 0 Primary.TSS
Transcriptional regulator kstR (Rv3574), TetR family
Induced -1 3.36 0 Primary.TSS
not assigned to any KEGG Pathway.
GO:0003677

DNA binding

DNA binding

Details: 
Any molecular function by which a gene product interacts selectively with DNA (deoxyribonucleic acid).
GO Category: 
molecular_function
37
Total items in this category:  
GO:0042803

protein homodimerization activity

protein homodimerization activity

Details: 
Interacting selectively and non-covalently with an identical protein to form a homodimer.
GO Category: 
molecular_function
83
Total items in this category:  
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.17 U
D3I 3 3 3.83 11.79 I
D3U 3 3 3.83 10.90 U
D5I 9 5 6.00 10.89 I
D5U 17 5 6.00 11.76 U
D7I 18 7 8.14 10.15 I
D7U 19 7 8.14 11.31 U
D14I 4 14 15.63 4.32 I
D14U 4 14 15.63 8.47 U
D17I 3 17 19.15 2.30 I
D17U 3 17 19.15 7.41 U
D21I 4 21 23.23 2.50 I
D21U 4 21 23.23 7.03 U
D24I 3 24 26.60 I
D24U 3 24 26.60 5.82 U
D28I 4 28 30.61 I
D28U 4 28 30.61 5.94 U