Module 217 Residual: 0.47

Title Bicluster Model Residual Score
bicluster_0217 v02 0.47 -32.75
Displaying 1 - 8 of 8
Rv2118c RNA methyltransferase

Details for Rv2118c - RNA methyltransferase

GO Terms: GO:0005886, GO:0008757, GO:0016429, GO:0030488, GO:0051289

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.85 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2118c

Tuberculist Genomic Region

Rv2119 RecB family exonuclease

Details for Rv2119 - RecB family exonuclease

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.93 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2119

Tuberculist Genomic Region

Rv1567c

Details for Rv1567c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1567c

Tuberculist Genomic Region

Rv1568 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)

Details for Rv1568 - Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)

GO Terms: GO:0004015, GO:0004015, GO:0051289

PATRIC Pathways: Biotin metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: 0.32

Go to Gene Page: Rv1568

Tuberculist Genomic Region

Rv1569 8-amino-7-oxononanoate synthase (EC 2.3.1.47)

Details for Rv1569 - 8-amino-7-oxononanoate synthase (EC 2.3.1.47)

GO Terms: GO:0008710, GO:0005886, GO:0008710

PATRIC Pathways: Biotin metabolism

Essentiality: Griffin Essential: 0.36 | In vitro Essential: NA | In vivo Essential: 0.03

Go to Gene Page: Rv1569

Tuberculist Genomic Region

Rv1570 Dethiobiotin synthetase (EC 6.3.3.3)

Details for Rv1570 - Dethiobiotin synthetase (EC 6.3.3.3)

GO Terms: GO:0004141

PATRIC Pathways: Biotin metabolism

Essentiality: Griffin Essential: 0.22 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1570

Tuberculist Genomic Region

Rv1571

Details for Rv1571 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.17 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1571

Tuberculist Genomic Region

Rv3199c NADH pyrophosphatase (EC 3.6.1.22)

Details for Rv3199c - NADH pyrophosphatase (EC 3.6.1.22)

GO Terms: GO:0000210, GO:0005886

PATRIC Pathways: Nicotinate and nicotinamide metabolism

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3199c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.00032 e-value: 0.091
Displaying 1 - 1 of 1
Possible transcriptional regulatory protein
regulates 46 modules
Weight: 
0.15
up-regulates
Disease resistance domain-containing protein / Transcriptional regulator, LuxR family
regulates 26 modules
Weight: 
0.15
up-regulates
COG0714: MoxR-like ATPases
regulates 31 modules
Weight: 
0.13
up-regulates
Arginine pathway regulatory protein ArgR, repressor of arg regulon
regulates 31 modules
Weight: 
0.12
up-regulates
Regulator of polyketide synthase expression
regulates 10 modules
Weight: 
0.11
up-regulates
\Transcriptional regulator, XRE family\\\""
regulates 9 modules
Weight: 
-0.09
down-regulates
Possible oxidoreductase subunit
regulates 12 modules
Weight: 
0.06
up-regulates
Transcriptional regulatory protein
regulates 18 modules
Weight: 
0.05
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0006766 | GO:0006767 | GO:0009110 | GO:0042364 | GO:0051186 | GO:0046394 | GO:0016053 vitamin metabolic process | water-soluble vitamin metabolic process | vitamin biosynthetic process | water-soluble vitamin biosynthetic proce... | cofactor metabolic process | carboxylic acid biosynthetic process | organic acid biosynthetic process
Displaying 1 - 10 of 10
GO:0005886 |

plasma membrane

GO:0008757 |

S-adenosylmethionine-dependent methyltransferase activity

GO:0016429 |

tRNA (adenine-N1-)-methyltransferase activity

GO:0030488 |

tRNA methylation

GO:0051289 |

protein homotetramerization

GO:0004015 |

adenosylmethionine-8-amino-7-oxononanoate transaminase activity

GO:0008710 |

8-amino-7-oxononanoate synthase activity

GO:0004141 |

dethiobiotin synthase activity

GO:0000210 |

NAD+ diphosphatase activity