Module 308 Residual: 0.49

Title Bicluster Model Residual Score
bicluster_0308 v02 0.49 -23.44
Displaying 1 - 18 of 18
Rv1338 Glutamate racemase (EC 5.1.1.3)

Details for Rv1338 - Glutamate racemase (EC 5.1.1.3)

GO Terms: GO:0008881, GO:0008150, GO:0005515, GO:0005886, GO:0008657, GO:0008881

PATRIC Pathways: D-Glutamine and D-glutamate metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: 0.26

Go to Gene Page: Rv1338

Tuberculist Genomic Region

Rv2684 Na+/H+ antiporter NhaD type

Details for Rv2684 - Na+/H+ antiporter NhaD type

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2684

Tuberculist Genomic Region

Rv2685 Na+/H+ antiporter NhaD type

Details for Rv2685 - Na+/H+ antiporter NhaD type

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.85 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2685

Tuberculist Genomic Region

Rv3719 FAD/FMN-containing dehydrogenases

Details for Rv3719 - FAD/FMN-containing dehydrogenases

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3719

Tuberculist Genomic Region

Rv3720 Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)

Details for Rv3720 - Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.03 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3720

Tuberculist Genomic Region

Rv1334 Mec+

Details for Rv1334 - Mec+

GO Terms: GO:0008235, GO:0008270, GO:0019344

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1334

Tuberculist Genomic Region

Rv1336 Cysteine synthase B (EC 2.5.1.47)

Details for Rv1336 - Cysteine synthase B (EC 2.5.1.47)

GO Terms: GO:0004124, GO:0030170, GO:0033847, GO:0042803, GO:0043234

PATRIC Pathways: Cysteine and methionine metabolism, Sulfur metabolism

Essentiality: Griffin Essential: 0.91 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1336

Tuberculist Genomic Region

Rv1337 Rhomboid membrane family protein

Details for Rv1337 - Rhomboid membrane family protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.80 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1337

Tuberculist Genomic Region

Rv1769 L-gulono-1,4-lactone oxidase (EC 1.1.3.8)

Details for Rv1769 - L-gulono-1,4-lactone oxidase (EC 1.1.3.8)

GO Terms: GO:0005886

PATRIC Pathways: Ascorbate and aldarate metabolism

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1769

Tuberculist Genomic Region

Rv1770 Putative aminopeptidase

Details for Rv1770 - Putative aminopeptidase

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.88 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1770

Tuberculist Genomic Region

Rv1771 oxidoreductase, FAD-binding

Details for Rv1771 - oxidoreductase, FAD-binding

GO Terms: GO:0005618, GO:0005886, GO:0080049

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1771

Tuberculist Genomic Region

Rv2148c

Details for Rv2148c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.25 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2148c

Tuberculist Genomic Region

Rv2149c COG1496: Uncharacterized conserved protein

Details for Rv2149c - COG1496: Uncharacterized conserved protein

GO Terms: GO:0005618

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2149c

Tuberculist Genomic Region

Rv2682c 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7)

Details for Rv2682c - 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7)

GO Terms: GO:0008661, GO:0000287, GO:0008661, GO:0019288, GO:0030145, GO:0030975, GO:0040007

PATRIC Pathways: Terpenoid backbone biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.09 | In vivo Essential: NA

Go to Gene Page: Rv2682c

Tuberculist Genomic Region

Rv2683

Details for Rv2683 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2683

Tuberculist Genomic Region

Rv3733c MutT-like protein

Details for Rv3733c - MutT-like protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3733c

Tuberculist Genomic Region

Rv3734c Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase

Details for Rv3734c - Wax ester synthase/acyl-CoA:diacylglycerol acyltransferase

GO Terms: GO:0001666, GO:0004144, GO:0005886, GO:0045017, GO:0071731

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3734c

Tuberculist Genomic Region

Rv3735 Probable transmembrane protein

Details for Rv3735 - Probable transmembrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3735

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.00000028 e-value: 0.32
Displaying 1 - 1 of 1
regulates 40 modules
Weight: 
0.23
up-regulates
Phosphate transport system regulatory protein PhoU
regulates 11 modules
Weight: 
0.21
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 26 of 26
GO:0008881 |

glutamate racemase activity

GO:0008150 |

biological_process

GO:0005515 |

protein binding

GO:0005886 |

plasma membrane

GO:0008657 |

DNA topoisomerase (ATP-hydrolyzing) inhibitor activity

GO:0008235 |

metalloexopeptidase activity

GO:0008270 |

zinc ion binding

GO:0019344 |

cysteine biosynthetic process

GO:0004124 |

cysteine synthase activity

GO:0030170 |

pyridoxal phosphate binding

GO:0033847 |

O-phosphoserine sulfhydrylase activity

GO:0042803 |

protein homodimerization activity

GO:0043234 |

protein complex

GO:0005618 |

cell wall

GO:0080049 |

L-gulono-1,4-lactone dehydrogenase activity

GO:0008661 |

1-deoxy-D-xylulose-5-phosphate synthase activity

GO:0000287 |

magnesium ion binding

GO:0019288 |

isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway

GO:0030145 |

manganese ion binding

GO:0030975 |

thiamine binding

GO:0040007 |

growth

GO:0001666 |

response to hypoxia

GO:0004144 |

diacylglycerol O-acyltransferase activity

GO:0045017 |

glycerolipid biosynthetic process

GO:0071731 |

response to nitric oxide