Module 439 Residual: 0.56

Title Bicluster Model Residual Score
bicluster_0439 v02 0.56 -18.79
Displaying 1 - 15 of 15
Rv0432 Superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1)

Details for Rv0432 - Superoxide dismutase [Cu-Zn] precursor (EC 1.15.1.1)

GO Terms: GO:0004784, GO:0005886, GO:0006979, GO:0033194, GO:0045454, GO:0052059, GO:0052060, GO:0075136, GO:0046872

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0432

Tuberculist Genomic Region

Rv3031 Glycogen branching enzyme, GH-57-type, archaeal (EC 2.4.1.18)

Details for Rv3031 - Glycogen branching enzyme, GH-57-type, archaeal (EC 2.4.1.18)

GO Terms: GO:0003844, GO:0005576, GO:0005886, GO:0040007

PATRIC Pathways: Starch and sucrose metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv3031

Tuberculist Genomic Region

Rv0433 Carboxylate-amine ligase

Details for Rv0433 - Carboxylate-amine ligase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0433

Tuberculist Genomic Region

Rv1098c Fumarate hydratase class II (EC 4.2.1.2)

Details for Rv1098c - Fumarate hydratase class II (EC 4.2.1.2)

GO Terms: GO:0004333, GO:0005576, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Citrate cycle (TCA cycle), Reductive carboxylate cycle (CO2 fixation)

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.11 | In vivo Essential: NA

Go to Gene Page: Rv1098c

Tuberculist Genomic Region

Rv2000

Details for Rv2000 -

GO Terms: GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2000

Tuberculist Genomic Region

Rv2001 Acyl-ACP thioesterase, FatA

Details for Rv2001 - Acyl-ACP thioesterase, FatA

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.40 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2001

Tuberculist Genomic Region

Rv2002 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase (EC 1.1.1.53)

Details for Rv2002 - 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase (EC 1.1.1.53)

GO Terms: GO:0005886, GO:0008202, GO:0047044

PATRIC Pathways: C21-Steroid hormone metabolism

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2002

Tuberculist Genomic Region

Rv2271

Details for Rv2271 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2271

Tuberculist Genomic Region

Rv2299c Chaperone protein HtpG

Details for Rv2299c - Chaperone protein HtpG

GO Terms: GO:0005524, GO:0006457, GO:0051082, GO:0005576, GO:0005886, GO:0071451

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2299c

Tuberculist Genomic Region

Rv2357c Glycyl-tRNA synthetase (EC 6.1.1.14)

Details for Rv2357c - Glycyl-tRNA synthetase (EC 6.1.1.14)

GO Terms: GO:0004820, GO:0005886, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.18 | In vivo Essential: NA

Go to Gene Page: Rv2357c

Tuberculist Genomic Region

Rv3029c Electron transfer flavoprotein, beta subunit

Details for Rv3029c - Electron transfer flavoprotein, beta subunit

GO Terms: GO:0009055, GO:0006118, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.18 | In vivo Essential: NA

Go to Gene Page: Rv3029c

Tuberculist Genomic Region

Rv3030 Methyltransferase (EC 2.1.1.-)
Rv3715c Recombination protein RecR

Details for Rv3715c - Recombination protein RecR

GO Terms: GO:0006281, GO:0003676, GO:0006310, GO:0006304

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3715c

Tuberculist Genomic Region

Rv3716c

Details for Rv3716c -

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3716c

Tuberculist Genomic Region

Rv3722c Aspartate transaminase (EC 2.6.1.1)
Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.00021 e-value: 0.0026
Displaying 1 - 1 of 1
Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR
regulates 90 modules
Weight: 
0.18
up-regulates
Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system
regulates 24 modules
Weight: 
0.16
up-regulates
response regulator
regulates 69 modules
Weight: 
0.13
up-regulates
Phenylacetic acid degradation operon negative regulatory protein PaaX
regulates 1 modules
Weight: 
-0.12
down-regulates
Possible transcriptional regulatory protein
regulates 46 modules
Weight: 
0.12
up-regulates
RNA polymerase sigma-54 factor RpoN
regulates 5 modules
Weight: 
-0.11
down-regulates
Transcriptional regulator, TetR family
regulates 12 modules
Weight: 
0.10
up-regulates
RNA polymerase sigma-70 factor, ECF subfamily
regulates 16 modules
Weight: 
-0.07
down-regulates
regulates 18 modules
Weight: 
0.07
up-regulates
Transcriptional regulator, MarR family
regulates 11 modules
Weight: 
0.05
up-regulates
RNA polymerase sigma-54 factor RpoN
regulates 27 modules
Weight: 
0.05
up-regulates
Transcriptional regulator, MarR family
regulates 19 modules
Weight: 
0.04
up-regulates
regulates 26 modules
Weight: 
0.03
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 29 of 29
GO:0004784 |

superoxide dismutase activity

GO:0005886 |

plasma membrane

GO:0006979 |

response to oxidative stress

GO:0033194 |

response to hydroperoxide

GO:0045454 |

cell redox homeostasis

GO:0052059 |

evasion or tolerance by symbiont of host-produced reactive oxygen species

GO:0052060 |

evasion or tolerance by symbiont of host-produced nitric oxide

GO:0075136 |

response to host

GO:0046872 |

metal ion binding

GO:0003844 |

1,4-alpha-glucan branching enzyme activity

GO:0005576 |

extracellular region

GO:0040007 |

growth

GO:0004333 |

fumarate hydratase activity

GO:0005829 |

cytosol

GO:0005618 |

cell wall

GO:0008202 |

steroid metabolic process

GO:0047044 |

androstan-3-alpha,17-beta-diol dehydrogenase activity

GO:0005524 |

ATP binding

GO:0006457 |

protein folding

GO:0051082 |

unfolded protein binding

GO:0071451 |

cellular response to superoxide

GO:0004820 |

glycine-tRNA ligase activity

GO:0009055 |

electron carrier activity

GO:0006118 |

electron transport

GO:0006281 |

DNA repair

GO:0003676 |

nucleic acid binding

GO:0006310 |

DNA recombination

GO:0006304 |

DNA modification