Module 485 Residual: 0.51

Title Bicluster Model Residual Score
bicluster_0485 v02 0.51 -12.18
Displaying 1 - 19 of 19
Rv0211 Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32)

Details for Rv0211 - Phosphoenolpyruvate carboxykinase [GTP] (EC 4.1.1.32)

GO Terms: GO:0004613, GO:0005576, GO:0005829, GO:0005886, GO:0010106, GO:0052572

PATRIC Pathways: Glycolysis / Gluconeogenesis, Pyruvate metabolism, Citrate cycle (TCA cycle)

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0211

Tuberculist Genomic Region

Rv0485 Transcriptional regulatory protein

Details for Rv0485 - Transcriptional regulatory protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0485

Tuberculist Genomic Region

Rv2729c Putative conserved alanine, valine and leucine rich integral membrane protein

Details for Rv2729c - Putative conserved alanine, valine and leucine rich integral membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2729c

Tuberculist Genomic Region

Rv0145

Details for Rv0145 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.61 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0145

Tuberculist Genomic Region

Rv0146

Details for Rv0146 -

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0146

Tuberculist Genomic Region

Rv0147 Aldehyde dehydrogenase (EC 1.2.1.3)
Rv0148 Short-chain dehydrogenase/reductase SDR

Details for Rv0148 - Short-chain dehydrogenase/reductase SDR

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0148

Tuberculist Genomic Region

Rv0149 Quinone oxidoreductase (EC 1.6.5.5)

Details for Rv0149 - Quinone oxidoreductase (EC 1.6.5.5)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.16 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0149

Tuberculist Genomic Region

Rv1460 Iron-sulfur cluster regulator SufR

Details for Rv1460 - Iron-sulfur cluster regulator SufR

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.13 | In vitro Essential: NA | In vivo Essential: 0.34

Go to Gene Page: Rv1460

Tuberculist Genomic Region

Rv1463 Iron-sulfur cluster assembly ATPase protein SufC

Details for Rv1463 - Iron-sulfur cluster assembly ATPase protein SufC

GO Terms: GO:0016887, GO:0005524, GO:0005515, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv1463

Tuberculist Genomic Region

Rv1594 Quinolinate synthetase (EC 2.5.1.72)

Details for Rv1594 - Quinolinate synthetase (EC 2.5.1.72)

GO Terms: GO:0008987, GO:0009435, GO:0008987, GO:0040007, GO:0051539

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv1594

Tuberculist Genomic Region

Rv2428 Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)

Details for Rv2428 - Alkyl hydroperoxide reductase protein C (EC 1.6.4.-)

GO Terms: GO:0004601, GO:0005515, GO:0005886, GO:0008785, GO:0032843, GO:0045454, GO:0051260, GO:0051409, GO:0051920, GO:0055114

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.47 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2428

Tuberculist Genomic Region

Rv2429 Alkylhydroperoxidase protein D

Details for Rv2429 - Alkylhydroperoxidase protein D

GO Terms: GO:0005515, GO:0005886, GO:0032843, GO:0042803, GO:0045454, GO:0070207

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2429

Tuberculist Genomic Region

Rv2518c Lipoprotein LppS

Details for Rv2518c - Lipoprotein LppS

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2518c

Tuberculist Genomic Region

Rv2640c Arsenical resistance operon repressor

Details for Rv2640c - Arsenical resistance operon repressor

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.86 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2640c

Tuberculist Genomic Region

Rv2705c Glutathione S-transferase domain protein

Details for Rv2705c - Glutathione S-transferase domain protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2705c

Tuberculist Genomic Region

Rv2706c

Details for Rv2706c -

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2706c

Tuberculist Genomic Region

Rv2707 Ribonuclease BN (EC 3.1.-.-)

Details for Rv2707 - Ribonuclease BN (EC 3.1.-.-)

GO Terms: GO:0005618, GO:0046812

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: 0.19

Go to Gene Page: Rv2707

Tuberculist Genomic Region

Rv3484 Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556)

Details for Rv3484 - Cell envelope-associated transcriptional attenuator LytR-CpsA-Psr, subfamily A1 (as in PMID19099556)

GO Terms: GO:0005576, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: 0.25

Go to Gene Page: Rv3484

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.00012 e-value: 0.068
Displaying 1 - 1 of 1
WhiB-like transcription regulator
regulates 13 modules
Weight: 
0.06
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 27 of 27
GO:0004613 |

phosphoenolpyruvate carboxykinase (GTP) activity

GO:0005576 |

extracellular region

GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0010106 |

cellular response to iron ion starvation

GO:0052572 |

response to host immune response

GO:0004029 |

aldehyde dehydrogenase (NAD) activity

GO:0005618 |

cell wall

GO:0016887 |

ATPase activity

GO:0005524 |

ATP binding

GO:0005515 |

protein binding

GO:0040007 |

growth

GO:0008987 |

quinolinate synthetase A activity

GO:0009435 |

NAD biosynthetic process

GO:0051539 |

4 iron, 4 sulfur cluster binding

GO:0004601 |

peroxidase activity

GO:0008785 |

alkyl hydroperoxide reductase activity

GO:0032843 |

hydroperoxide reductase activity

GO:0045454 |

cell redox homeostasis

GO:0051260 |

protein homooligomerization

GO:0051409 |

response to nitrosative stress

GO:0051920 |

peroxiredoxin activity

GO:0055114 |

oxidation-reduction process

GO:0042803 |

protein homodimerization activity

GO:0070207 |

protein homotrimerization

GO:0046812 |

host cell surface binding