Module 593 Residual: 0.58

Title Bicluster Model Residual Score
bicluster_0593 v02 0.58 -7.13
Displaying 1 - 19 of 19
Rv0245 Nitrilotriacetate monooxygenase component B (EC 1.14.13.-)
Rv0474 \Transcriptional regulator, XRE family\\\""

Details for Rv0474 - \Transcriptional regulator, XRE family\\\""

GO Terms: GO:0005829

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0474

Tuberculist Genomic Region

Rv0475 Iron-regulated heparin binding hemagglutinin HbhA (Adhesin)

Details for Rv0475 - Iron-regulated heparin binding hemagglutinin HbhA (Adhesin)

GO Terms: GO:0005515, GO:0005618, GO:0005829, GO:0005886, GO:0007157, GO:0008201, GO:0009986, GO:0042803, GO:0044078

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0475

Tuberculist Genomic Region

Rv0711 Arylsulfatase (EC 3.1.6.1)

Details for Rv0711 - Arylsulfatase (EC 3.1.6.1)

GO Terms: GO:0005886, GO:0010033

PATRIC Pathways: C21-Steroid hormone metabolism, Sphingolipid metabolism

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0711

Tuberculist Genomic Region

Rv0805 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)

Details for Rv0805 - 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)

GO Terms: GO:0004115, GO:0005506, GO:0008199, GO:0009405, GO:0030145, GO:0042301, GO:0042803

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0805

Tuberculist Genomic Region

Rv0983 Heat shock protein HtrA

Details for Rv0983 - Heat shock protein HtrA

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.91 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0983

Tuberculist Genomic Region

Rv0984 Molybdenum cofactor biosynthesis protein MoaB

Details for Rv0984 - Molybdenum cofactor biosynthesis protein MoaB

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.27 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0984

Tuberculist Genomic Region

Rv1245c Short-chain type dehydrogenase/reductase

Details for Rv1245c - Short-chain type dehydrogenase/reductase

GO Terms: GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1245c

Tuberculist Genomic Region

Rv1531 Carboxymuconolactone decarboxylase

Details for Rv1531 - Carboxymuconolactone decarboxylase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.40 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1531

Tuberculist Genomic Region

Rv1732c Alkyl hydroperoxide reductase and/or thiol-specific antioxidant family (AhpC/TSA) protein

Details for Rv1732c - Alkyl hydroperoxide reductase and/or thiol-specific antioxidant family (AhpC/TSA) protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1732c

Tuberculist Genomic Region

Rv2373c Chaperone protein DnaJ

Details for Rv2373c - Chaperone protein DnaJ

GO Terms: GO:0031072, GO:0006457, GO:0051082, GO:0040007, GO:0010468

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.01 | In vitro Essential: 0.14 | In vivo Essential: NA

Go to Gene Page: Rv2373c

Tuberculist Genomic Region

Rv2728c

Details for Rv2728c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2728c

Tuberculist Genomic Region

Rv2729c Putative conserved alanine, valine and leucine rich integral membrane protein

Details for Rv2729c - Putative conserved alanine, valine and leucine rich integral membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2729c

Tuberculist Genomic Region

Rv3009c Aspartyl-tRNA(Asn) amidotransferase subunit B (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit B (EC 6.3.5.7)

Details for Rv3009c - Aspartyl-tRNA(Asn) amidotransferase subunit B (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit B (EC 6.3.5.7)

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis, Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv3009c

Tuberculist Genomic Region

Rv3138 COG1180: Radical SAM, Pyruvate-formate lyase-activating enzyme like

Details for Rv3138 - COG1180: Radical SAM, Pyruvate-formate lyase-activating enzyme like

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.93 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3138

Tuberculist Genomic Region

Rv3139 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)

Details for Rv3139 - Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)

GO Terms: GO:0005618, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.52 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv3139

Tuberculist Genomic Region

Rv3140 Probable acyl-CoA dehydrogenase (EC 1.3.99.3)

Details for Rv3140 - Probable acyl-CoA dehydrogenase (EC 1.3.99.3)

GO Terms: GO:0003995, GO:0005886, GO:0040007

PATRIC Pathways: Fatty acid metabolism, Valine, leucine and isoleucine degradation, beta-Alanine metabolism, Propanoate metabolism

Essentiality: Griffin Essential: 0.08 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv3140

Tuberculist Genomic Region

Rv3645 Adenylate cyclase (EC 4.6.1.1)

Details for Rv3645 - Adenylate cyclase (EC 4.6.1.1)

GO Terms: GO:0004016, GO:0004016

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3645

Tuberculist Genomic Region

Rv3879c RD1 region associated protein Rv3879c

Details for Rv3879c - RD1 region associated protein Rv3879c

GO Terms: GO:0005515, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.26 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3879c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 4900 e-value: 7400
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 25 of 25
GO:0005829 |

cytosol

GO:0005515 |

protein binding

GO:0005618 |

cell wall

GO:0005886 |

plasma membrane

GO:0007157 |

heterophilic cell-cell adhesion

GO:0008201 |

heparin binding

GO:0009986 |

cell surface

GO:0042803 |

protein homodimerization activity

GO:0044078 |

positive regulation by symbiont of host receptor-mediated endocytosis

GO:0010033 |

response to organic substance

GO:0004115 |

3',5'-cyclic-AMP phosphodiesterase activity

GO:0005506 |

iron ion binding

GO:0008199 |

ferric iron binding

GO:0009405 |

pathogenesis

GO:0030145 |

manganese ion binding

GO:0042301 |

phosphate ion binding

GO:0005576 |

extracellular region

GO:0031072 |

heat shock protein binding

GO:0006457 |

protein folding

GO:0051082 |

unfolded protein binding

GO:0040007 |

growth

GO:0010468 |

regulation of gene expression

GO:0003995 |

acyl-CoA dehydrogenase activity

GO:0004016 |

adenylate cyclase activity