Rv2034 Transcriptional regulator, ArsR family

Rv2034 (Transcriptional regulator, ArsR family) is predicted to be co-regulated in modules bicluster_0120 with residual 0.55 and bicluster_0546 with residual 0.58.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.00 and 0.00 for bicluster_0120 and 0.00 and 0.21 for bicluster_0546 respectively.

These modules are enriched for following go terms: nucleic acid binding transcription facto..., sequence-specific DNA binding transcript... .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 61 - 70 of 150
Gene Target Differential Expression Distance Expression pvalue Type
3-ketoacyl-CoA thiolase (EC 2.3.1.16) @ Acetyl-CoA acetyltransferase (EC 2.3.1.9)
No 68 0.03 0.824821 Primary.TSS
Transcriptional regulatory protein
No -58 0.55 0.00000558 CDS
Metal-dependent hydrolases of the beta-lactamase superfamily III
No 23 -0.02 0.945388 Internal.TSS
NLP/P60 family protein
No -35 0.07 0.716539 Primary.TSS
No -6 -0.63 0.172399 Primary.TSS
Alcohol dehydrogenase (EC 1.1.1.1)
No -147 -0.11 0.62553 CDS
No -28 -0.7 0.0500055 CDS
Probable phiRV1 phage protein
No -44 -0.06 0.915867 CDS
Adenylate cyclase (EC 4.6.1.1)
Induced 2 1.48 1.45e-27 Primary.TSS
No -64 -0.14 0.560643 Internal.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 10.48 U
D3I 3 3 3.83 10.74 I
D3U 3 3 3.83 10.88 U
D5I 9 5 6.00 8.69 I
D5U 17 5 6.00 10.11 U
D7I 18 7 8.14 6.93 I
D7U 19 7 8.14 9.41 U
D14I 4 14 15.63 2.80 I
D14U 4 14 15.63 9.76 U
D17I 3 17 19.15 I
D17U 3 17 19.15 9.50 U
D21I 4 21 23.23 2.16 I
D21U 4 21 23.23 9.28 U
D24I 3 24 26.60 I
D24U 3 24 26.60 9.11 U
D28I 4 28 30.61 I
D28U 4 28 30.61 8.90 U