Rv2989 Transcriptional regulator, IclR family

Rv2989 (Transcriptional regulator, IclR family) is predicted to be co-regulated in modules bicluster_0286 with residual 0.44 and bicluster_0344 with residual 0.49.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 4.30 and 5.80 for bicluster_0286 and 0.10 and 8.00 for bicluster_0344 respectively.

These modules are enriched for following go terms: branched-chain amino acid biosynthetic p..., branched-chain amino acid metabolic proc..., cytosol, cytosolic part .

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 51 - 60 of 72
Gene Target Differential Expression Distance Expression pvalue Type
Transcriptional regulator, AsnC family
No -4 0.13 0.895345 CDS
Transcriptional regulator, AsnC family
No 38 0.13 0.895345 Internal.TSS
Alanine dehydrogenase (EC 1.4.1.1)
No -49 0.36 0.644263 Primary.TSS
3-isopropylmalate dehydratase large subunit (EC 4.2.1.33)
No 2 -1.72 0.152484 Primary.TSS
Transcriptional regulator, IclR family
Induced 3 1.78 0.0215465 Primary.TSS
ATPase
No 12 0.03 0.97455 CDS
No 29 0.01 0.99697 Primary.TSS
No 29 0 0.99931 Internal.TSS
WhiB-like transcription regulator
No 57 0.11 0.932186 Primary.TSS
Dihydrolipoamide dehydrogenase (EC 1.8.1.4)
Repressed -28 -1.08 0.000000000154 Primary.TSS
not assigned to any KEGG Pathway.
GO:0005886

plasma membrane

plasma membrane

Details: 
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO Category: 
cellular_component
1284
Total items in this category:  
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 11.99 U
D3I 3 3 3.83 12.29 I
D3U 3 3 3.83 12.15 U
D5I 9 5 6.00 9.55 I
D5U 17 5 6.00 10.00 U
D7I 18 7 8.14 10.53 I
D7U 19 7 8.14 11.10 U
D14I 4 14 15.63 6.98 I
D14U 4 14 15.63 9.98 U
D17I 3 17 19.15 5.52 I
D17U 3 17 19.15 9.61 U
D21I 4 21 23.23 5.39 I
D21U 4 21 23.23 9.29 U
D24I 3 24 26.60 4.03 I
D24U 3 24 26.60 8.97 U
D28I 4 28 30.61 4.56 I
D28U 4 28 30.61 9.30 U