Module 165 Residual: 0.44

Title Bicluster Model Residual Score
bicluster_0165 v02 0.44 -15.90
Displaying 1 - 18 of 18
Rv0598c Toxin 1, PIN domain

Details for Rv0598c - Toxin 1, PIN domain

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.59 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0598c

Tuberculist Genomic Region

Rv0599c

Details for Rv0599c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0599c

Tuberculist Genomic Region

Rv2682c 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7)

Details for Rv2682c - 1-deoxy-D-xylulose 5-phosphate synthase (EC 2.2.1.7)

GO Terms: GO:0008661, GO:0000287, GO:0008661, GO:0019288, GO:0030145, GO:0030975, GO:0040007

PATRIC Pathways: Terpenoid backbone biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.09 | In vivo Essential: NA

Go to Gene Page: Rv2682c

Tuberculist Genomic Region

Rv2683

Details for Rv2683 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2683

Tuberculist Genomic Region

Rv3147 NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)

Details for Rv3147 - NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)

GO Terms: GO:0008137, GO:0005829

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.59 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3147

Tuberculist Genomic Region

Rv3148 NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)

Details for Rv3148 - NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)

GO Terms: GO:0008137, GO:0005886

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3148

Tuberculist Genomic Region

Rv3149 NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)

Details for Rv3149 - NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)

GO Terms: GO:0008137

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3149

Tuberculist Genomic Region

Rv3150 NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)

Details for Rv3150 - NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)

GO Terms: GO:0008137

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.03 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3150

Tuberculist Genomic Region

Rv3151 NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)

Details for Rv3151 - NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)

GO Terms: GO:0008137, GO:0005618, GO:0005886, GO:0009405, GO:0033668

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.06 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3151

Tuberculist Genomic Region

Rv3152 NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)

Details for Rv3152 - NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)

GO Terms: GO:0008137

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.06 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3152

Tuberculist Genomic Region

Rv3153 NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3)

Details for Rv3153 - NADH-ubiquinone oxidoreductase chain I (EC 1.6.5.3)

GO Terms: GO:0008137, GO:0005829

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.16 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3153

Tuberculist Genomic Region

Rv3154 NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)

Details for Rv3154 - NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)

GO Terms: GO:0008137, GO:0005887

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3154

Tuberculist Genomic Region

Rv3155 NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)

Details for Rv3155 - NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)

GO Terms: GO:0008137

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.32 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3155

Tuberculist Genomic Region

Rv3156 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)

Details for Rv3156 - NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)

GO Terms: GO:0008137, GO:0052572

PATRIC Pathways: Oxidative phosphorylation

Essentiality: Griffin Essential: 0.24 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3156

Tuberculist Genomic Region

Rv3200c Potassium channel protein

Details for Rv3200c - Potassium channel protein

GO Terms: GO:0005829, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.24 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3200c

Tuberculist Genomic Region

Rv3870 FtsK/SpoIIIE family protein Rv3870, component of ESX-1 secretion system

Details for Rv3870 - FtsK/SpoIIIE family protein Rv3870, component of ESX-1 secretion system

GO Terms: GO:0008150, GO:0005515, GO:0005886, GO:0009405, GO:0042783, GO:0044110, GO:0044117, GO:0052083

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.70 | In vitro Essential: NA | In vivo Essential: 0.34

Go to Gene Page: Rv3870

Tuberculist Genomic Region

Rv3871 FtsK/SpoIIIE family protein Rv3871, component of ESX-1 secretion system

Details for Rv3871 - FtsK/SpoIIIE family protein Rv3871, component of ESX-1 secretion system

GO Terms: GO:0008150, GO:0005515, GO:0005576, GO:0005886, GO:0009405, GO:0042783, GO:0044110, GO:0044117, GO:0052083

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: 0.19

Go to Gene Page: Rv3871

Tuberculist Genomic Region

Rv2290 Probable conserved lipoprotein lppOb

Details for Rv2290 - Probable conserved lipoprotein lppOb

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2290

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.025 e-value: 0.071
Displaying 1 - 1 of 1
Transcriptional regulator, TetR family
regulates 12 modules
Weight: 
0.43
up-regulates
\Transcriptional regulator, XRE family\\\""
regulates 9 modules
Weight: 
-0.22
down-regulates
RNA polymerase sigma-70 factor
regulates 8 modules
Weight: 
0.18
up-regulates
COG0714: MoxR-like ATPases
regulates 31 modules
Weight: 
0.17
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0006796 | GO:0006793 | GO:0051287 phosphate-containing compound metabolic ... | phosphorus metabolic process | NAD binding
Displaying 1 - 22 of 22
GO:0008661 |

1-deoxy-D-xylulose-5-phosphate synthase activity

GO:0000287 |

magnesium ion binding

GO:0019288 |

isopentenyl diphosphate biosynthetic process, mevalonate-independent pathway

GO:0030145 |

manganese ion binding

GO:0030975 |

thiamine binding

GO:0040007 |

growth

GO:0008137 |

NADH dehydrogenase (ubiquinone) activity

GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0005618 |

cell wall

GO:0009405 |

pathogenesis

GO:0033668 |

negative regulation by symbiont of host apoptotic process

GO:0005887 |

integral to plasma membrane

GO:0052572 |

response to host immune response

GO:0008150 |

biological_process

GO:0005515 |

protein binding

GO:0042783 |

active evasion of host immune response

GO:0044110 |

growth involved in symbiotic interaction

GO:0044117 |

growth of symbiont in host

GO:0052083 |

negative regulation by symbiont of host cell-mediated immune response

GO:0005576 |

extracellular region