Module 301 Residual: 0.61

Title Bicluster Model Residual Score
bicluster_0301 v02 0.61 -8.24
Displaying 1 - 18 of 18
Rv0201c

Details for Rv0201c -

GO Terms: GO:0044119

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0201c

Tuberculist Genomic Region

Rv0202c Transmembrane transport protein MmpL13

Details for Rv0202c - Transmembrane transport protein MmpL13

GO Terms: GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0202c

Tuberculist Genomic Region

Rv0203 POSSIBLE EXPORTED PROTEIN

Details for Rv0203 - POSSIBLE EXPORTED PROTEIN

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.86 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0203

Tuberculist Genomic Region

Rv0583c Lipoprotein LpqN

Details for Rv0583c - Lipoprotein LpqN

GO Terms: GO:0005576, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0583c

Tuberculist Genomic Region

Rv0633c Possible membrane protein

Details for Rv0633c - Possible membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0633c

Tuberculist Genomic Region

Rv0951 Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5)

Details for Rv0951 - Succinyl-CoA ligase [ADP-forming] beta chain (EC 6.2.1.5)

GO Terms: GO:0004775, GO:0005618, GO:0005829, GO:0040007

PATRIC Pathways: Propanoate metabolism, Citrate cycle (TCA cycle), Reductive carboxylate cycle (CO2 fixation), C5-Branched dibasic acid metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv0951

Tuberculist Genomic Region

Rv2450c Putative saccharopine dehydrogenase

Details for Rv2450c - Putative saccharopine dehydrogenase

GO Terms: GO:0005576, GO:0010628, GO:0010629, GO:0040010

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2450c

Tuberculist Genomic Region

Rv2584c Adenine phosphoribosyltransferase (EC 2.4.2.7)

Details for Rv2584c - Adenine phosphoribosyltransferase (EC 2.4.2.7)

GO Terms: GO:0003999, GO:0005886

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2584c

Tuberculist Genomic Region

Rv3274c Butyryl-CoA dehydrogenase (EC 1.3.99.2)

Details for Rv3274c - Butyryl-CoA dehydrogenase (EC 1.3.99.2)

GO Terms: GO:0004085, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3274c

Tuberculist Genomic Region

Rv3472

Details for Rv3472 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: 0.36

Go to Gene Page: Rv3472

Tuberculist Genomic Region

Rv3485c short chain dehydrogenase

Details for Rv3485c - short chain dehydrogenase

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3485c

Tuberculist Genomic Region

Rv0547c \Oxidoreductase, short-chain dehydrogenase/reductase family\\\""

Details for Rv0547c - \Oxidoreductase, short-chain dehydrogenase/reductase family\\\""

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0547c

Tuberculist Genomic Region

Rv0952 Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)

Details for Rv0952 - Succinyl-CoA ligase [ADP-forming] alpha chain (EC 6.2.1.5)

GO Terms: GO:0004775, GO:0005618, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: C5-Branched dibasic acid metabolism, Reductive carboxylate cycle (CO2 fixation), Citrate cycle (TCA cycle), Propanoate metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.17 | In vivo Essential: NA

Go to Gene Page: Rv0952

Tuberculist Genomic Region

Rv2352c PPE family protein

Details for Rv2352c - PPE family protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2352c

Tuberculist Genomic Region

Rv2725c GTP-binding protein HflX

Details for Rv2725c - GTP-binding protein HflX

GO Terms: GO:0005525, GO:0005622, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.93 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2725c

Tuberculist Genomic Region

Rv3036c Possible membrane protein

Details for Rv3036c - Possible membrane protein

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3036c

Tuberculist Genomic Region

Rv3436c Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)

Details for Rv3436c - Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)

GO Terms: GO:0004360, GO:0005886, GO:0040007

PATRIC Pathways: Alanine, aspartate and glutamate metabolism, Amino sugar and nucleotide sugar metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv3436c

Tuberculist Genomic Region

Rv3440c

Details for Rv3440c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3440c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.00091 e-value: 4.4
Displaying 1 - 1 of 1
Transcriptional regulator, TetR family
regulates 54 modules
Weight: 
0.32
up-regulates
Uracil phosphoribosyltransferase (EC 2.4.2.9) / Pyrimidine operon regulatory protein PyrR
regulates 90 modules
Weight: 
0.16
up-regulates
Transcriptional regulator, TetR family
regulates 19 modules
Weight: 
0.16
up-regulates
Single-stranded DNA-binding protein
regulates 26 modules
Weight: 
0.15
up-regulates
RNA polymerase sigma factor SigB
regulates 61 modules
Weight: 
0.07
up-regulates
response regulator
regulates 69 modules
Weight: 
0.06
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0070838 | GO:0072511 | GO:0000041 | GO:0072509 divalent metal ion transport | divalent inorganic cation transport | transition metal ion transport | divalent inorganic cation transmembrane ...
Displaying 1 - 16 of 16
GO:0044119 |

growth of symbiont in host cell

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0005576 |

extracellular region

GO:0004775 |

succinate-CoA ligase (ADP-forming) activity

GO:0040007 |

growth

GO:0010628 |

positive regulation of gene expression

GO:0010629 |

negative regulation of gene expression

GO:0040010 |

positive regulation of growth rate

GO:0003999 |

adenine phosphoribosyltransferase activity

GO:0004085 |

butyryl-CoA dehydrogenase activity

GO:0005525 |

GTP binding

GO:0005622 |

intracellular

GO:0004360 |

glutamine-fructose-6-phosphate transaminase (isomerizing) activity