Rv0023 Transcriptional regulatory protein

Rv0023 (Transcriptional regulatory protein) is predicted to be co-regulated in modules bicluster_0304 with residual 0.58 and bicluster_0544 with residual 0.41.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.36 and 78.00 for bicluster_0304 and 420.00 and 780.00 for bicluster_0544 respectively.

These modules are enriched for following go terms: cellular ketone metabolic process cellular homeostasis, homeostatic process, regulation of biological quality, electron carrier activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 131 - 140 of 174
Gene Target Differential Expression Distance Expression pvalue Type
Long-chain fatty-acid-CoA ligase (EC 6.2.1.3), Mycobacterial subgroup FadD22
Repressed -75 -1.15 0.0000208 Internal.TSS
Pyruvate carboxyl transferase (EC 6.4.1.1)
Repressed -38 -1.35 3.83e-25 CDS
Putative uncharacterized protein BCG_3011c
Repressed 11 -1.44 0.000330266 Primary.TSS
Induced -97 0.75 0.00181184 Primary.TSS
Multidrug resistance protein mmr
Induced 1 0.75 0.0136544 Primary.TSS
Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)
No 5 -0.41 0.358315 Internal.TSS
NADH:flavin oxidoreductases, Old Yellow Enzyme family
No -57 -0.25 0.23684 CDS
transcriptional regulator, AfsR/DnrI/RedD family
No -88 0.22 0.39331 Internal.TSS
No -10 -0.48 0.0223072 Primary.TSS
Probable response regulator
No -118 -0.38 0.392573 CDS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.35 U
D3I 3 3 3.83 11.63 I
D3U 3 3 3.83 11.40 U
D5I 9 5 6.00 12.32 I
D5U 17 5 6.00 12.61 U
D7I 18 7 8.14 8.45 I
D7U 19 7 8.14 11.60 U
D14I 4 14 15.63 6.26 I
D14U 4 14 15.63 9.95 U
D17I 3 17 19.15 5.13 I
D17U 3 17 19.15 9.94 U
D21I 4 21 23.23 5.32 I
D21U 4 21 23.23 9.06 U
D24I 3 24 26.60 4.70 I
D24U 3 24 26.60 9.32 U
D28I 4 28 30.61 5.55 I
D28U 4 28 30.61 8.40 U