Rv0023 Transcriptional regulatory protein

Rv0023 (Transcriptional regulatory protein) is predicted to be co-regulated in modules bicluster_0304 with residual 0.58 and bicluster_0544 with residual 0.41.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.36 and 78.00 for bicluster_0304 and 420.00 and 780.00 for bicluster_0544 respectively.

These modules are enriched for following go terms: cellular ketone metabolic process cellular homeostasis, homeostatic process, regulation of biological quality, electron carrier activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 101 - 110 of 174
Gene Target Differential Expression Distance Expression pvalue Type
Proteasome subunit beta (EC 3.4.25.1), bacterial
No -144 -0.5 0.000636584 Primary.TSS
PE family protein
No 31 -0.42 0.0305841 Primary.TSS
Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)
No -67 -0.41 0.26014 Primary.TSS
Possible membrane protein
Induced -149 2.4 1.46e-16 CDS
No 65 0.17 0.530206 Primary.TSS
Putative cystathionine beta-lyase (EC 4.4.1.8)
No -150 0.38 0.286306 CDS
NG,NG-dimethylarginine dimethylaminohydrolase 1 (EC 3.5.3.18)
Repressed 36 -1.29 0.000012 Internal.TSS
NG,NG-dimethylarginine dimethylaminohydrolase 1 (EC 3.5.3.18)
Repressed -24 -1.29 0.000012 CDS
SSU ribosomal protein S20p
No -37 0.4 0.231095 Primary.TSS
Repressed 11 -1.1 0.00203342 Internal.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.35 U
D3I 3 3 3.83 11.63 I
D3U 3 3 3.83 11.40 U
D5I 9 5 6.00 12.32 I
D5U 17 5 6.00 12.61 U
D7I 18 7 8.14 8.45 I
D7U 19 7 8.14 11.60 U
D14I 4 14 15.63 6.26 I
D14U 4 14 15.63 9.95 U
D17I 3 17 19.15 5.13 I
D17U 3 17 19.15 9.94 U
D21I 4 21 23.23 5.32 I
D21U 4 21 23.23 9.06 U
D24I 3 24 26.60 4.70 I
D24U 3 24 26.60 9.32 U
D28I 4 28 30.61 5.55 I
D28U 4 28 30.61 8.40 U