Rv0023 Transcriptional regulatory protein

Rv0023 (Transcriptional regulatory protein) is predicted to be co-regulated in modules bicluster_0304 with residual 0.58 and bicluster_0544 with residual 0.41.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.36 and 78.00 for bicluster_0304 and 420.00 and 780.00 for bicluster_0544 respectively.

These modules are enriched for following go terms: cellular ketone metabolic process cellular homeostasis, homeostatic process, regulation of biological quality, electron carrier activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 161 - 170 of 174
Gene Target Differential Expression Distance Expression pvalue Type
Terminal oxygenase KshA
Induced -41 2.23 6.99e-20 Primary.TSS
PPE family protein
No -8 0.41 0.00256419 Primary.TSS
Acyl-CoA dehydrogenase (EC 1.3.99.-)
No 64 0.09 0.619383 CDS
Transcriptional regulator kstR (Rv3574), TetR family
No -12 0.17 0.61049 Primary.TSS
Histone protein Lsr2
No 35 0.35 0.114939 Primary.TSS
Dolichol-phosphate mannosyltransferase (EC 2.4.1.83) in lipid-linked oligosaccharide synthesis cluster
Repressed 5 -1.38 0.00000000000243 CDS
Adenylate cyclase (EC 4.6.1.1)
No -23 0.23 0.184032 CDS
Adenylate cyclase (EC 4.6.1.1)
No -83 0.23 0.184032 Internal.TSS
PPE family protein
No -39 -0.17 0.572974 Antisense.TSS
Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4)
Induced 33 2.39 0 CDS
not assigned to any KEGG Pathway.
No TFOE experiment results were found

TRIP log2 fold abundance change

NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.35 U
D3I 3 3 3.83 11.63 I
D3U 3 3 3.83 11.40 U
D5I 9 5 6.00 12.32 I
D5U 17 5 6.00 12.61 U
D7I 18 7 8.14 8.45 I
D7U 19 7 8.14 11.60 U
D14I 4 14 15.63 6.26 I
D14U 4 14 15.63 9.95 U
D17I 3 17 19.15 5.13 I
D17U 3 17 19.15 9.94 U
D21I 4 21 23.23 5.32 I
D21U 4 21 23.23 9.06 U
D24I 3 24 26.60 4.70 I
D24U 3 24 26.60 9.32 U
D28I 4 28 30.61 5.55 I
D28U 4 28 30.61 8.40 U