Rv0023 Transcriptional regulatory protein

Rv0023 (Transcriptional regulatory protein) is predicted to be co-regulated in modules bicluster_0304 with residual 0.58 and bicluster_0544 with residual 0.41.

This regulation is possibly mediated by two de-novo identified cis-regulatory motifs in each module with e-values , 0.36 and 78.00 for bicluster_0304 and 420.00 and 780.00 for bicluster_0544 respectively.

These modules are enriched for following go terms: cellular ketone metabolic process cellular homeostasis, homeostatic process, regulation of biological quality, electron carrier activity.

This gene is found to be for growth on cholesterol.

Mutant available?:

Displaying 91 - 100 of 174
Gene Target Differential Expression Distance Expression pvalue Type
Transcriptional repressor Mce3R, TetR family
Induced 46 0.96 0.000990388 Primary.TSS
Ribonucleotide reductase of class Ib (aerobic), beta subunit (EC 1.17.4.1)
No 58 0.48 0.118484 Primary.TSS
Transporter, LysE family
Induced -8 2.89 7.94e-22 Primary.TSS
Transcriptional regulator, ArsR family
Induced 11 1.12 0.00015683 Primary.TSS
Induced -146 1.35 2.49e-24 CDS
Repressed 52 -1.26 0.00161016 CDS
No -13 0.15 0.70846 Primary.TSS
No -144 -0.49 0.419013 CDS
Transcriptional regulator, ArsR family
Induced -27 2.78 0.000000000000317 CDS
No -127 0.01 0.986118 Primary.TSS
not assigned to any KEGG Pathway.
No TFOE experiment results were found
TRIP log2 fold abundance change
NA
Displaying 1 - 17 of 17
Condition Count Day Doublings Fitness U.I Plots
D0U 27 0 0.00 12.35 U
D3I 3 3 3.83 11.63 I
D3U 3 3 3.83 11.40 U
D5I 9 5 6.00 12.32 I
D5U 17 5 6.00 12.61 U
D7I 18 7 8.14 8.45 I
D7U 19 7 8.14 11.60 U
D14I 4 14 15.63 6.26 I
D14U 4 14 15.63 9.95 U
D17I 3 17 19.15 5.13 I
D17U 3 17 19.15 9.94 U
D21I 4 21 23.23 5.32 I
D21U 4 21 23.23 9.06 U
D24I 3 24 26.60 4.70 I
D24U 3 24 26.60 9.32 U
D28I 4 28 30.61 5.55 I
D28U 4 28 30.61 8.40 U