Module 158 Residual: 0.52

Title Bicluster Model Residual Score
bicluster_0158 v02 0.52 -4.05
Displaying 1 - 19 of 19
Rv0188 PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Details for Rv0188 - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0188

Tuberculist Genomic Region

Rv0270 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv0270 - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0005886

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0270

Tuberculist Genomic Region

Rv0426c Possible membrane protein

Details for Rv0426c - Possible membrane protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0426c

Tuberculist Genomic Region

Rv1086 Undecaprenyl pyrophosphate synthetase (EC 2.5.1.31)

Details for Rv1086 - Undecaprenyl pyrophosphate synthetase (EC 2.5.1.31)

GO Terms: GO:0008834, GO:0000287, GO:0005829, GO:0005886, GO:0016094, GO:0030145, GO:0033850

PATRIC Pathways: Terpenoid backbone biosynthesis

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1086

Tuberculist Genomic Region

Rv1843c Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)

Details for Rv1843c - Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205)

GO Terms: GO:0003938, GO:0005829, GO:0005886

PATRIC Pathways: Purine metabolism, Drug metabolism - other enzymes

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1843c

Tuberculist Genomic Region

Rv2182c 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

Details for Rv2182c - 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

GO Terms: GO:0003841, GO:0005886, GO:0040007

PATRIC Pathways: Glycerolipid metabolism, Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.14 | In vivo Essential: NA

Go to Gene Page: Rv2182c

Tuberculist Genomic Region

Rv2342

Details for Rv2342 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2342

Tuberculist Genomic Region

Rv2495c Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)

Details for Rv2495c - Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (EC 2.3.1.168)

GO Terms: GO:0008415, GO:0005515, GO:0008152, GO:0005886, GO:0004739

PATRIC Pathways: Valine, leucine and isoleucine degradation

Essentiality: Griffin Essential: 0.38 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2495c

Tuberculist Genomic Region

Rv2496c Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)

Details for Rv2496c - Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit (EC 1.2.4.4)

GO Terms: GO:0003863, GO:0005515, GO:0005886, GO:0004739

PATRIC Pathways: Valine, leucine and isoleucine degradation

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2496c

Tuberculist Genomic Region

Rv2497c Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)

Details for Rv2497c - Branched-chain alpha-keto acid dehydrogenase, E1 component, alpha subunit (EC 1.2.4.4)

GO Terms: GO:0003863, GO:0005515, GO:0004739

PATRIC Pathways: Valine, leucine and isoleucine degradation

Essentiality: Griffin Essential: 0.50 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2497c

Tuberculist Genomic Region

Rv2694c

Details for Rv2694c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.40 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2694c

Tuberculist Genomic Region

Rv2731 ATPase involved in DNA repair

Details for Rv2731 - ATPase involved in DNA repair

GO Terms: GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2731

Tuberculist Genomic Region

Rv3241c Ribosomal subunit interface protein

Details for Rv3241c - Ribosomal subunit interface protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3241c

Tuberculist Genomic Region

Rv3596c ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence clcC/mecB

Details for Rv3596c - ATP-dependent Clp protease, ATP-binding subunit ClpC / Negative regulator of genetic competence clcC/mecB

GO Terms: GO:0006289, GO:0005515, GO:0004518, GO:0019538, GO:0003677, GO:0005524, GO:0005515, GO:0005829, GO:0005886, GO:0016887, GO:0040007, GO:0042803, GO:0044183

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.18 | In vivo Essential: NA

Go to Gene Page: Rv3596c

Tuberculist Genomic Region

Rv3814c 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

Details for Rv3814c - 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

GO Terms: GO:0005886

PATRIC Pathways: Glycerolipid metabolism, Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3814c

Tuberculist Genomic Region

Rv3816c 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

Details for Rv3816c - 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)

GO Terms: GO:0003841, GO:0005886

PATRIC Pathways: Glycerophospholipid metabolism, Glycerolipid metabolism

Essentiality: Griffin Essential: 0.20 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3816c

Tuberculist Genomic Region

Rv2743c Possible conserved membrane alanine rich protein

Details for Rv2743c - Possible conserved membrane alanine rich protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2743c

Tuberculist Genomic Region

Rv2744c Phage shock protein A (IM30) , suppresses sigma54-dependent transcription

Details for Rv2744c - Phage shock protein A (IM30) , suppresses sigma54-dependent transcription

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2744c

Tuberculist Genomic Region

Rv2745c Transcriptional regulator, XRE family

Details for Rv2745c - Transcriptional regulator, XRE family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2745c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 20000 e-value: 33000
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0004738 | GO:0004739 | GO:0016624 pyruvate dehydrogenase activity | pyruvate dehydrogenase (acetyl-transferr... | oxidoreductase activity, acting on the a...
Displaying 1 - 25 of 25
GO:0005886 |

plasma membrane

GO:0008834 |

di-trans,poly-cis-decaprenylcistransferase activity

GO:0000287 |

magnesium ion binding

GO:0005829 |

cytosol

GO:0016094 |

polyprenol biosynthetic process

GO:0030145 |

manganese ion binding

GO:0033850 |

Z-farnesyl diphosphate synthase activity

GO:0003938 |

IMP dehydrogenase activity

GO:0003841 |

1-acylglycerol-3-phosphate O-acyltransferase activity

GO:0040007 |

growth

GO:0008415 |

NA

GO:0005515 |

protein binding

GO:0008152 |

metabolic process

GO:0004739 |

pyruvate dehydrogenase (acetyl-transferring) activity

GO:0003863 |

3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity

GO:0005618 |

cell wall

GO:0006289 |

nucleotide-excision repair

GO:0004518 |

nuclease activity

GO:0019538 |

protein metabolic process

GO:0003677 |

DNA binding

GO:0005524 |

ATP binding

GO:0016887 |

ATPase activity

GO:0042803 |

protein homodimerization activity

GO:0044183 |

protein binding involved in protein folding