Module 187 Residual: 0.50

Title Bicluster Model Residual Score
bicluster_0187 v02 0.50 -18.07
Displaying 1 - 16 of 16
Rv0435c Cell division protein FtsH (EC 3.4.24.-)

Details for Rv0435c - Cell division protein FtsH (EC 3.4.24.-)

GO Terms: GO:0008150, GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0435c

Tuberculist Genomic Region

Rv0436c CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8)

Details for Rv0436c - CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8)

GO Terms: GO:0003882, GO:0005576

PATRIC Pathways: Glycine, serine and threonine metabolism, Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.03 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0436c

Tuberculist Genomic Region

Rv0437c Phosphatidylserine decarboxylase (EC 4.1.1.65)

Details for Rv0437c - Phosphatidylserine decarboxylase (EC 4.1.1.65)

GO Terms: GO:0004609, GO:0005886

PATRIC Pathways: Glycerophospholipid metabolism

Essentiality: Griffin Essential: 0.06 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0437c

Tuberculist Genomic Region

Rv0803 Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)

Details for Rv0803 - Phosphoribosylformylglycinamidine synthase, synthetase subunit (EC 6.3.5.3)

GO Terms: GO:0004642, GO:0006164, GO:0040007

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv0803

Tuberculist Genomic Region

Rv0804 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)

Details for Rv0804 - 3',5'-cyclic-nucleotide phosphodiesterase (EC 3.1.4.17)

GO Terms: NA

PATRIC Pathways: Purine metabolism

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0804

Tuberculist Genomic Region

Rv1227c transmembrane protein, distant homology with ydbS

Details for Rv1227c - transmembrane protein, distant homology with ydbS

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1227c

Tuberculist Genomic Region

Rv1228 PUTATIVE LIPOPROTEIN LPQX

Details for Rv1228 - PUTATIVE LIPOPROTEIN LPQX

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1228

Tuberculist Genomic Region

Rv2265

Details for Rv2265 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2265

Tuberculist Genomic Region

Rv0777 Adenylosuccinate lyase (EC 4.3.2.2)

Details for Rv0777 - Adenylosuccinate lyase (EC 4.3.2.2)

GO Terms: GO:0004018, GO:0005618, GO:0005886

PATRIC Pathways: Alanine, aspartate and glutamate metabolism, Purine metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0777

Tuberculist Genomic Region

Rv0778 Cytochrome P450 126A3

Details for Rv0778 - Cytochrome P450 126A3

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0778

Tuberculist Genomic Region

Rv0802c

Details for Rv0802c -

GO Terms: GO:0006104, GO:0051289

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.21 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0802c

Tuberculist Genomic Region

Rv1226c transmembrane protein, distant homology with ydbT

Details for Rv1226c - transmembrane protein, distant homology with ydbT

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.61 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1226c

Tuberculist Genomic Region

Rv1231c PROBABLE MEMBRANE PROTEIN

Details for Rv1231c - PROBABLE MEMBRANE PROTEIN

GO Terms: GO:0005618, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.59 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1231c

Tuberculist Genomic Region

Rv1232c Mg/Co/Ni transporter MgtE / CBS domain

Details for Rv1232c - Mg/Co/Ni transporter MgtE / CBS domain

GO Terms: GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: 0.16 | In vivo Essential: NA

Go to Gene Page: Rv1232c

Tuberculist Genomic Region

Rv1689 Tyrosyl-tRNA synthetase (EC 6.1.1.1)

Details for Rv1689 - Tyrosyl-tRNA synthetase (EC 6.1.1.1)

GO Terms: GO:0004831, GO:0005886, GO:0040007

PATRIC Pathways: Aminoacyl-tRNA biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv1689

Tuberculist Genomic Region

Rv2045c Probable carboxylesterase LipT (EC 3.1.1.-)

Details for Rv2045c - Probable carboxylesterase LipT (EC 3.1.1.-)

GO Terms: NA

PATRIC Pathways: 1,4-Dichlorobenzene degradation, Tropane, piperidine and pyridine alkaloid biosynthesis, Ascorbate and aldarate metabolism, 2,4-Dichlorobenzoate degradation, Glycerophospholipid metabolism, Bisphenol A degradation, Retinol metabolism

Essentiality: Griffin Essential: 0.60 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2045c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.0061 e-value: 0.16
Displaying 1 - 1 of 1
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0090407 | GO:0006644 | GO:0008654 organophosphate biosynthetic process | phospholipid metabolic process | phospholipid biosynthetic process
Displaying 1 - 14 of 14
GO:0008150 |

biological_process

GO:0005618 |

cell wall

GO:0005886 |

plasma membrane

GO:0003882 |

CDP-diacylglycerol-serine O-phosphatidyltransferase activity

GO:0005576 |

extracellular region

GO:0004609 |

phosphatidylserine decarboxylase activity

GO:0004642 |

phosphoribosylformylglycinamidine synthase activity

GO:0006164 |

purine nucleotide biosynthetic process

GO:0040007 |

growth

GO:0004018 |

N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity

GO:0006104 |

succinyl-CoA metabolic process

GO:0051289 |

protein homotetramerization

GO:0004831 |

tyrosine-tRNA ligase activity