Module 200 Residual: 0.45

Title Bicluster Model Residual Score
bicluster_0200 v02 0.45 -27.62
Displaying 1 - 15 of 15
Rv3504 FadE30

Details for Rv3504 - FadE30

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.99 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3504

Tuberculist Genomic Region

Rv3505 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)

Details for Rv3505 - Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.34 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3505

Tuberculist Genomic Region

Rv3515c Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv3515c - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0004467, GO:0004467, GO:0052572

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.93 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3515c

Tuberculist Genomic Region

Rv3516 Enoyl-CoA hydratase (EC 4.2.1.17)
Rv3527

Details for Rv3527 -

GO Terms: GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3527

Tuberculist Genomic Region

Rv3570c POSSIBLE OXIDOREDUCTASE

Details for Rv3570c - POSSIBLE OXIDOREDUCTASE

GO Terms: GO:0005886, GO:0044117

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.14 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3570c

Tuberculist Genomic Region

Rv3573c Acyl-CoA dehydrogenase (EC 1.3.99.-)

Details for Rv3573c - Acyl-CoA dehydrogenase (EC 1.3.99.-)

GO Terms: GO:0005886

PATRIC Pathways: Caprolactam degradation, Naphthalene and anthracene degradation, Fatty acid metabolism, Brassinosteroid biosynthesis, Benzoate degradation via hydroxylation, Valine, leucine and isoleucine degradation, Geraniol degradation

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3573c

Tuberculist Genomic Region

Rv3526 Terminal oxygenase KshA

Details for Rv3526 - Terminal oxygenase KshA

GO Terms: GO:0070723

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.75 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3526

Tuberculist Genomic Region

Rv3540c Lipid carrier protein IgrF

Details for Rv3540c - Lipid carrier protein IgrF

GO Terms: GO:0044117

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.91 | In vitro Essential: NA | In vivo Essential: 0.14

Go to Gene Page: Rv3540c

Tuberculist Genomic Region

Rv3543c Probable acyl-CoA dehydrogenase FadE29 (EC 1.3.99.-); Acyl-CoA dehydrogenase IgrC

Details for Rv3543c - Probable acyl-CoA dehydrogenase FadE29 (EC 1.3.99.-); Acyl-CoA dehydrogenase IgrC

GO Terms: GO:0044117

PATRIC Pathways: Valine, leucine and isoleucine degradation, Caprolactam degradation, Brassinosteroid biosynthesis, Geraniol degradation, Naphthalene and anthracene degradation, Fatty acid metabolism, Benzoate degradation via hydroxylation

Essentiality: Griffin Essential: 0.24 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3543c

Tuberculist Genomic Region

Rv3544c Probable acyl-CoA dehydrogenase FadE28 (EC 1.3.99.-); Acyl-CoA dehydrogenase IgrB

Details for Rv3544c - Probable acyl-CoA dehydrogenase FadE28 (EC 1.3.99.-); Acyl-CoA dehydrogenase IgrB

GO Terms: GO:0004085, GO:0009268, GO:0009405, GO:0044117

PATRIC Pathways: Fatty acid metabolism, Brassinosteroid biosynthesis, Benzoate degradation via hydroxylation, Caprolactam degradation, Geraniol degradation, Valine, leucine and isoleucine degradation, Naphthalene and anthracene degradation

Essentiality: Griffin Essential: 0.87 | In vitro Essential: NA | In vivo Essential: 0.04

Go to Gene Page: Rv3544c

Tuberculist Genomic Region

Rv3545c Putative cytochrome P450 125 (EC 1.14.-.-); Putative cytochrome P450 IgrA
Rv3546 Probable acetyl-CoA acetyltransferase FadA5 (EC 2.3.1.9)

Details for Rv3546 - Probable acetyl-CoA acetyltransferase FadA5 (EC 2.3.1.9)

GO Terms: GO:0003988

PATRIC Pathways: Reductive carboxylate cycle (CO2 fixation), Lysine degradation, Butanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Terpenoid backbone biosynthesis, Fatty acid metabolism, Synthesis and degradation of ketone bodies, Glyoxylate and dicarboxylate metabolism, Valine, leucine and isoleucine degradation, Benzoate degradation via hydroxylation, Propanoate metabolism

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3546

Tuberculist Genomic Region

Rv3568c 2,3-dihydroxybiphenyl 1,2-dioxygenase

Details for Rv3568c - 2,3-dihydroxybiphenyl 1,2-dioxygenase

GO Terms: GO:0016702, GO:0070723

PATRIC Pathways: Biphenyl degradation, gamma-Hexachlorocyclohexane degradation

Essentiality: Griffin Essential: 0.64 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3568c

Tuberculist Genomic Region

Rv3574 Transcriptional regulator kstR (Rv3574), TetR family

Details for Rv3574 - Transcriptional regulator kstR (Rv3574), TetR family

GO Terms: GO:0003677, GO:0042803

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: 0.09

Go to Gene Page: Rv3574

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 8.3e-28 e-value: 0.16
Displaying 1 - 1 of 1
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0050662 | GO:0016491 coenzyme binding | oxidoreductase activity
Displaying 1 - 14 of 14
GO:0005886 |

plasma membrane

GO:0004467 |

long-chain fatty acid-CoA ligase activity

GO:0052572 |

response to host immune response

GO:0004300 |

enoyl-CoA hydratase activity

GO:0044117 |

growth of symbiont in host

GO:0070723 |

response to cholesterol

GO:0004085 |

butyryl-CoA dehydrogenase activity

GO:0009268 |

response to pH

GO:0009405 |

pathogenesis

GO:0003988 |

acetyl-CoA C-acyltransferase activity

GO:0016702 |

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen

GO:0003677 |

DNA binding

GO:0042803 |

protein homodimerization activity