Module 288 Residual: 0.46

Title Bicluster Model Residual Score
bicluster_0288 v02 0.46 -6.77
Displaying 1 - 16 of 16
Rv0129c Antigen 85-C precursor (85C) (Antigen 85 complex C) (Ag85C) (Mycolyl transferase 85C) (EC 2.3.1.-)
Rv1157c

Details for Rv1157c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1157c

Tuberculist Genomic Region

Rv1158c Conserved alanine and proline rich protein

Details for Rv1158c - Conserved alanine and proline rich protein

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.27 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1158c

Tuberculist Genomic Region

Rv1433

Details for Rv1433 -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1433

Tuberculist Genomic Region

Rv1477 NLP/P60 family protein

Details for Rv1477 - NLP/P60 family protein

GO Terms: GO:0005515, GO:0005576, GO:0005618, GO:0008745, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv1477

Tuberculist Genomic Region

Rv1478 Invasion protein

Details for Rv1478 - Invasion protein

GO Terms: GO:0005618

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1478

Tuberculist Genomic Region

Rv1770 Putative aminopeptidase

Details for Rv1770 - Putative aminopeptidase

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.88 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1770

Tuberculist Genomic Region

Rv1771 oxidoreductase, FAD-binding

Details for Rv1771 - oxidoreductase, FAD-binding

GO Terms: GO:0005618, GO:0005886, GO:0080049

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1771

Tuberculist Genomic Region

Rv1987

Details for Rv1987 -

GO Terms: NA

PATRIC Pathways: NA

Essentiality: Griffin Essential: 0.72 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1987

Tuberculist Genomic Region

Rv2151c Cell division protein FtsQ homolog

Details for Rv2151c - Cell division protein FtsQ homolog

GO Terms: GO:0008150, GO:0005515, GO:0005829, GO:0005887, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv2151c

Tuberculist Genomic Region

Rv2154c Cell division protein FtsW

Details for Rv2154c - Cell division protein FtsW

GO Terms: GO:0008150, GO:0008150, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.03 | In vivo Essential: NA

Go to Gene Page: Rv2154c

Tuberculist Genomic Region

Rv2155c UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9)

Details for Rv2155c - UDP-N-acetylmuramoylalanine--D-glutamate ligase (EC 6.3.2.9)

GO Terms: GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0005515, GO:0005829, GO:0040007

PATRIC Pathways: D-Glutamine and D-glutamate metabolism, Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv2155c

Tuberculist Genomic Region

Rv2721c Possible conserved transmembrane alanine and glycine rich protein

Details for Rv2721c - Possible conserved transmembrane alanine and glycine rich protein

GO Terms: GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.97 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2721c

Tuberculist Genomic Region

Rv2927c Cell division initiation protein

Details for Rv2927c - Cell division initiation protein

GO Terms: GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.18 | In vivo Essential: NA

Go to Gene Page: Rv2927c

Tuberculist Genomic Region

Rv2152c UDP-N-acetylmuramate--alanine ligase (EC 6.3.2.8)

Details for Rv2152c - UDP-N-acetylmuramate--alanine ligase (EC 6.3.2.8)

GO Terms: GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0008763, GO:0040007

PATRIC Pathways: D-Glutamine and D-glutamate metabolism, Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.02 | In vivo Essential: NA

Go to Gene Page: Rv2152c

Tuberculist Genomic Region

Rv2153c UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227)

Details for Rv2153c - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227)

GO Terms: GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0008150, GO:0040007

PATRIC Pathways: Peptidoglycan biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv2153c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.23 e-value: 2800
Displaying 1 - 1 of 1
RNA polymerase sigma-70 factor
regulates 8 modules
Weight: 
0.36
up-regulates
Transcriptional regulator, ArsR family
regulates 28 modules
Weight: 
-0.24
down-regulates
Predicted regulator PutR for proline utilization, GntR family
regulates 11 modules
Weight: 
0.24
up-regulates
COG0714: MoxR-like ATPases
regulates 31 modules
Weight: 
0.17
up-regulates
Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system
regulates 24 modules
Weight: 
0.10
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0044085 | GO:0071840 | GO:0030246 | GO:0016881 cellular component biogenesis | cellular component organization or bioge... | carbohydrate binding | acid-amino acid ligase activity
Displaying 1 - 17 of 17
GO:0005576 |

extracellular region

GO:0005618 |

cell wall

GO:0006869 |

lipid transport

GO:0009247 |

glycolipid biosynthetic process

GO:0016747 |

transferase activity, transferring acyl groups other than amino-acyl groups

GO:0046677 |

response to antibiotic

GO:0071769 |

mycolate cell wall layer assembly

GO:0005515 |

protein binding

GO:0008745 |

N-acetylmuramoyl-L-alanine amidase activity

GO:0040007 |

growth

GO:0005886 |

plasma membrane

GO:0080049 |

L-gulono-1,4-lactone dehydrogenase activity

GO:0008150 |

biological_process

GO:0005829 |

cytosol

GO:0005887 |

integral to plasma membrane

GO:0008763 |

UDP-N-acetylmuramate-L-alanine ligase activity