Module 397 Residual: 0.58

Title Bicluster Model Residual Score
bicluster_0397 v02 0.58 -19.55
Displaying 1 - 18 of 18
Rv1419

Details for Rv1419 -

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1419

Tuberculist Genomic Region

Rv1977 Zn-dependent protease with chaperone function

Details for Rv1977 - Zn-dependent protease with chaperone function

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1977

Tuberculist Genomic Region

Rv0270 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv0270 - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0005886

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 1.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0270

Tuberculist Genomic Region

Rv0272c

Details for Rv0272c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.64 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0272c

Tuberculist Genomic Region

Rv0273c Transcriptional regulator, TetR family

Details for Rv0273c - Transcriptional regulator, TetR family

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.66 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0273c

Tuberculist Genomic Region

Rv0274 Glyoxalase family protein

Details for Rv0274 - Glyoxalase family protein

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.68 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0274

Tuberculist Genomic Region

Rv0389 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-)

Details for Rv0389 - Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-)

GO Terms: GO:0005829

PATRIC Pathways: Amino sugar and nucleotide sugar metabolism

Essentiality: Griffin Essential: 0.90 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0389

Tuberculist Genomic Region

Rv0390 Rhodanese-related sulfurtransferase

Details for Rv0390 - Rhodanese-related sulfurtransferase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.63 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0390

Tuberculist Genomic Region

Rv0676c Transmembrane transport protein MmpL5

Details for Rv0676c - Transmembrane transport protein MmpL5

GO Terms: GO:0005576, GO:0005829, GO:0005887

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.98 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0676c

Tuberculist Genomic Region

Rv0677c membrane protein, MmpS family

Details for Rv0677c - membrane protein, MmpS family

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0677c

Tuberculist Genomic Region

Rv0678

Details for Rv0678 -

GO Terms: GO:0006355

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.71 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0678

Tuberculist Genomic Region

Rv0834c PE-PGRS FAMILY PROTEIN

Details for Rv0834c - PE-PGRS FAMILY PROTEIN

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.83 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0834c

Tuberculist Genomic Region

Rv0937c Ku domain protein

Details for Rv0937c - Ku domain protein

GO Terms: GO:0003690, GO:0005515, GO:0006303, GO:0033202, GO:0042803

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.32 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0937c

Tuberculist Genomic Region

Rv0938 ATP-dependent DNA ligase (EC 6.5.1.1) clustered with Ku protein, LigD

Details for Rv0938 - ATP-dependent DNA ligase (EC 6.5.1.1) clustered with Ku protein, LigD

GO Terms: GO:0000287, GO:0003887, GO:0003896, GO:0003899, GO:0003909, GO:0003910, GO:0004652, GO:0005515, GO:0005524, GO:0005886, GO:0006269, GO:0006303, GO:0008310, GO:0030145

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0938

Tuberculist Genomic Region

Rv0939 Fumarylacetoacetase (EC 3.7.1.2)

Details for Rv0939 - Fumarylacetoacetase (EC 3.7.1.2)

GO Terms: GO:0004334, GO:0005829, GO:0005886

PATRIC Pathways: alpha-Linolenic acid metabolism, Tyrosine metabolism

Essentiality: Griffin Essential: 0.64 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0939

Tuberculist Genomic Region

Rv1989c

Details for Rv1989c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1989c

Tuberculist Genomic Region

Rv1990c

Details for Rv1990c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.05 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1990c

Tuberculist Genomic Region

Rv3917c Chromosome (plasmid) partitioning protein ParB / Stage 0 sporulation protein J

Details for Rv3917c - Chromosome (plasmid) partitioning protein ParB / Stage 0 sporulation protein J

GO Terms: GO:0008150, GO:0005576, GO:0005694, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv3917c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.000000000016 e-value: 0.000063
Displaying 1 - 1 of 1
Transcriptional regulator, FUR family
regulates 9 modules
Weight: 
0.10
up-regulates
Transcriptional regulator, TetR family
regulates 9 modules
Weight: 
0.10
up-regulates
Lactate-responsive regulator LldR in Enterobacteria, GntR family
regulates 28 modules
Weight: 
0.09
up-regulates
HTH-type transcriptional regulator
regulates 17 modules
Weight: 
0.08
up-regulates
Transcriptional regulator, ArsR family
regulates 28 modules
Weight: 
0.08
up-regulates
regulates 14 modules
Weight: 
0.07
up-regulates
Adenylyl cyclase class-3/4/guanylyl cyclase / Disease resistance domain-containing protein / Tetratricopeptide repeat-containing protein / Transcriptional regulator, LuxR family
regulates 11 modules
Weight: 
0.07
up-regulates
Nicotinamide-nucleotide adenylyltransferase, NadR family (EC 2.7.7.1) / Ribosylnicotinamide kinase (EC 2.7.1.22)
regulates 6 modules
Weight: 
0.07
up-regulates
Phosphate regulon transcriptional regulatory protein PhoB (SphR); Sensory transduction protein regX3
regulates 7 modules
Weight: 
0.06
up-regulates
Transcriptional regulator, TetR family
regulates 9 modules
Weight: 
0.06
up-regulates
DNA-binding response regulator
regulates 5 modules
Weight: 
0.05
up-regulates
DNA-binding response regulator, LuxR family
regulates 29 modules
Weight: 
0.05
up-regulates
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
GO:0006807 | GO:0016835 nitrogen compound metabolic process | carbon-oxygen lyase activity
Displaying 1 - 26 of 26
GO:0005576 |

extracellular region

GO:0005886 |

plasma membrane

GO:0005829 |

cytosol

GO:0005887 |

integral to plasma membrane

GO:0006355 |

regulation of transcription, DNA-dependent

GO:0003690 |

double-stranded DNA binding

GO:0005515 |

protein binding

GO:0006303 |

double-strand break repair via nonhomologous end joining

GO:0033202 |

DNA helicase complex

GO:0042803 |

protein homodimerization activity

GO:0000287 |

magnesium ion binding

GO:0003887 |

DNA-directed DNA polymerase activity

GO:0003896 |

DNA primase activity

GO:0003899 |

DNA-directed RNA polymerase activity

GO:0003909 |

DNA ligase activity

GO:0003910 |

DNA ligase (ATP) activity

GO:0004652 |

polynucleotide adenylyltransferase activity

GO:0005524 |

ATP binding

GO:0006269 |

DNA replication, synthesis of RNA primer

GO:0008310 |

single-stranded DNA specific 3'-5' exodeoxyribonuclease activity

GO:0030145 |

manganese ion binding

GO:0004334 |

fumarylacetoacetase activity

GO:0008150 |

biological_process

GO:0005694 |

chromosome

GO:0040007 |

growth