Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 181 - 190 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Title	Gene Count	Motif 1 e-value	Motif 2 e-value	Residual	TF Influences
Module_294	26 CD630_10460 - pepT Type: Gene Product:Peptidase T \| Pathway: \| COG: Amino acid transport and metabolism CD630_26450 - Type: Gene Product:ABC-type transport system, sugar-familyextracellular solute-binding protein \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_30330 - trxA Type: Gene Product:Thioredoxin \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_30350 - Type: Gene Product:Putative diaminopimelate epimerase, PhzF family \| Pathway: \| COG: Function unknown CD630_04530 - Type: Gene Product:Putative hydrolase \| Pathway: \| COG: Nucleotide transport and metabolism CD630_04510 - Type: Gene Product:Putative dioxygenase \| Pathway: \| COG: Function unknown CD630_19700 - Type: Gene Product:Putative enzyme, cyclase family \| Pathway: \| COG: Amino acid transport and metabolism CD630_19690 - Type: Gene Product:Putative oligonucleotide binding regulator \| Pathway: \| COG: Function unknown CD630_32810 - proC Type: Gene Product:Pyrroline-5-carboxylate reductase \| Pathway: Amino-acid biosynthesis \| COG: Amino acid transport and metabolism CD630_07140 - Type: Gene Product:Putative protein involved in protein-proteininteractions \| Pathway: \| COG: Function unknown CD630_16290 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_02020 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_06270 - Type: Gene Product:Putative transcriptional regulator, activatorMor \| Pathway: \| COG: CD630_07121 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_17670 - gapB Type: Gene Product:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_26460 - ftsZ Type: Gene Product:Cell division protein FtsZ \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_30340 - Type: Gene Product:Transcriptional regulator, TrmB family \| Pathway: \| COG: Transcription CD630_21150 - Type: Gene Product:Putative copper-transporting P-type ATPase \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_04520 - Type: Gene Product:Putative hydrolase, NUDIX family \| Pathway: \| COG: Nucleotide transport and metabolism CD630_15780 - Type: Gene Product:Putative membrane-associated ribonuclease BN-like(Rbn) \| Pathway: \| COG: Function unknown CD630_10450 - Type: Gene Product:Putative sporulation integral membrane protein \| Pathway: \| COG: Function unknown CD630_19670 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_07150 - ptb Type: Gene Product:Phosphate butyryltransferase(Phosphotransbutyrylase) \| Pathway: \| COG: Energy production and conversion CD630_06260 - Type: Gene Product:Putative replicative helicase DnaB-like \| Pathway: \| COG: Replication, recombination and repair CD630_19680 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_07130 - Type: Gene Product:Putative radical SAM domain-containing protein \| Pathway: \| COG: Energy production and conversion	0.00000012	0.00043	0.49	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_18100 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_29	15 CD630_10960 - Type: Gene Product:ABC-type transport system, multidrug-familypermease Tn1549-like, CTn4-Orf29 \| Pathway: \| COG: Function unknown CD630_33640 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Function unknown CD630_10970 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein Tn1549-like, CTn4-Orf28 \| Pathway: \| COG: Defense mechanisms CD630_33620 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Function unknown CD630_10950 - Type: Gene Product:ABC-type transport system, multidrug-familypermease Tn1549-like, CTn4-Orf30 \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_33680 - Type: Gene Product:Putative ribosome biogenesis GTPase RsgA;putative EngC-like GTPase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_33630 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Function unknown CD630_10991 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf25 \| Pathway: \| COG: Function unknown CD630_10990 - Type: Gene Product:Two-component response regulator, Tn1549-like,CTn4-Orf26 \| Pathway: \| COG: Signal transduction mechanisms CD630_33681 - Type: Gene Product:Putative zinc finger protein \| Pathway: \| COG: Function unknown CD630_10980 - Type: Gene Product:Two-component sensor histidine kinase,Tn1549-like, CTn4-Orf27 \| Pathway: \| COG: Signal transduction mechanisms CD630_03810 - Type: Gene Product:Putative replication initiation factorTn916-like, CTn1-Orf26 \| Pathway: \| COG: Transcription CD630_03790 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn1-Orf24 \| Pathway: \| COG: Function unknown CD630_11000 - Type: Gene Product:Transcriptional regulator, HTH-type Tn1549-like,CTn4-Orf24 \| Pathway: \| COG: Transcription CD630_03800 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn1-Orf25 \| Pathway: \| COG: Function unknown	0.000037	0.000066	0.49	Inferelator: 3 Hypergeometric: 0 TF Influences from Inferelator CD630_02760 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_05310 - Type: Gene Product:Transcriptional regulator, DeoR family \| Pathway: \| COG: Transcription CD630_32800 - Type: Gene Product:Sigma-54 dpendent regulator, PTS fructose family \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_232	25 CD630_36490 - rlmH Type: Gene Product:Ribosomal RNA large subunit methyltransferase H,SPOUT methyltransferase family \| Pathway: \| COG: Function unknown CD630_32000 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Function unknown CD630_16080 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: CD630_36530 - dnaD Type: Gene Product:DNA replication protein DnaD/DnaB \| Pathway: \| COG: Replication, recombination and repair CD630_36510 - Type: Gene Product:Putative metallo-beta-lactamase-like hydrolase \| Pathway: \| COG: Function unknown CD630_16100 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_16060 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_06150 - Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription CD630_35610 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_32010 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_16090 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_30240 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_27920 - secA2 Type: Gene Product:Protein translocase secA 2 \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_36500 - Type: Gene Product:PTS system, lactose/cellobiose-family IICcomponent \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_31590 - Type: Gene Product:Putative FemA-like peptidoglycan biosynthesisprotein \| Pathway: \| COG: Function unknown CD630_36540 - dnaC Type: Gene Product:DNA replication protein DnaC \| Pathway: \| COG: Replication, recombination and repair CD630_36520 - Type: Gene Product:Putative peptidase, M1 family \| Pathway: \| COG: Amino acid transport and metabolism CD630_t0650 - tRNA-Ala Type: Gene Product: \| Pathway: \| COG: CD630_16070 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_16110 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_17870 - Type: Gene Product:Transcriptional regulator, MerR family \| Pathway: \| COG: Transcription CD630_18850 - Type: Gene Product:Putative acetylesterase \| Pathway: \| COG: Function unknown CD630_06160 - Type: Gene Product:Transcriptional regulator, MerR family \| Pathway: \| COG: Transcription CD630_06140 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_30230 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG:	0.0000000000000025	3.1	0.50	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_02760 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_30940 - Type: Gene Product:Transcriptional regulator, sigma-54-dependent \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_81	18 CD630_23900 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription CD630_24540 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_25320 - Type: Gene Product:Aminotransferase, alanine--glyoxylatetransaminase \| Pathway: \| COG: Amino acid transport and metabolism CD630_23880 - Type: Gene Product:Putative peptidoglycan-binding/hydrolysingprotein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_25300 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_24510 - Type: Gene Product:Putative CRISPR-associated ATP-dependenthelicase \| Pathway: \| COG: Replication, recombination and repair CD630_25310 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_25290 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_t0250 - tRNA-Met Type: Gene Product: \| Pathway: \| COG: CD630_24530 - Type: Gene Product:Putative CRISPR-associated negativeautoregulator \| Pathway: \| COG: Replication, recombination and repair CD630_15180 - feoA Type: Gene Product:Ferrous iron transport protein \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_24520 - Type: Gene Product:Putative CRISPR-associated protein \| Pathway: \| COG: Replication, recombination and repair CD630_06840 - Type: Gene Product:Putative ATP-dependent peptidase, M41 family \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_23890 - Type: Gene Product:Putative beta-lactams signal-transducer \| Pathway: \| COG: Transcription, Signal transduction mechanisms CD630_15120 - panC Type: Gene Product:Pantothenate synthetase \| Pathway: Cofactor biosynthesis \| COG: Coenzyme transport and metabolism CD630_15170 - feoB Type: Gene Product:Ferrous iron transport protein B \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_15130 - panB Type: Gene Product:Ketopantoate hydroxymethyltransferase \| Pathway: Cofactor biosynthesis \| COG: Coenzyme transport and metabolism CD630_15140 - panG Type: Gene Product:Putative ketopantoate reductase \| Pathway: \| COG: Coenzyme transport and metabolism	0.0000088	`NA`	0.50	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_23900 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_33	18 CD630_t0070 - tRNA-Gly Type: Gene Product: \| Pathway: \| COG: CD630_t0350 - tRNA-Gln Type: Gene Product: \| Pathway: \| COG: CD630_t0150 - tRNA-Ser Type: Gene Product: \| Pathway: \| COG: CD630_t0330 - tRNA-Gly Type: Gene Product: \| Pathway: \| COG: CD630_t0780 - tRNA-Arg Type: Gene Product: \| Pathway: \| COG: CD630_t0400 - tRNA-Met Type: Gene Product: \| Pathway: \| COG: CD630_t0320 - tRNA-Leu Type: Gene Product: \| Pathway: \| COG: CD630_t0110 - tRNA-Tyr Type: Gene Product: \| Pathway: \| COG: CD630_t0580 - tRNA-Ser Type: Gene Product: \| Pathway: \| COG: CD630_t0340 - tRNA-Arg Type: Gene Product: \| Pathway: \| COG: CD630_t0390 - tRNA-Met Type: Gene Product: \| Pathway: \| COG: CD630_t0120 - tRNA-Leu Type: Gene Product: \| Pathway: \| COG: CD630_t0200 - tRNA-His Type: Gene Product: \| Pathway: \| COG: CD630_t0410 - tRNA-His Type: Gene Product: \| Pathway: \| COG: CD630_t0300 - tRNA-Thr Type: Gene Product: \| Pathway: \| COG: CD630_t0590 - tRNA-Pro Type: Gene Product: \| Pathway: \| COG: CD630_t0310 - tRNA-Tyr Type: Gene Product: \| Pathway: \| COG:	0	0	0.50	Inferelator: 0 Hypergeometric: 0 TF Influences from Inferelator `No TF influences from Inferelator` TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_98	23 CD630_27260 - glyA Type: Gene Product:Serine hydroxymethyltransferase \| Pathway: One-carbon metabolism \| COG: Amino acid transport and metabolism CD630_10030 - fumA Type: Gene Product:Fumarate hydratase class I, subunit A \| Pathway: \| COG: Energy production and conversion CD630_22080 - Type: Gene Product:Transcriptional regulator, MarR family \| Pathway: \| COG: Transcription CD630_17500 - Type: Gene Product:Putative CoA enzyme activase \| Pathway: \| COG: Lipid transport and metabolism CD630_10050 - Type: Gene Product:Putative NAD-dependent malic enzyme \| Pathway: \| COG: Energy production and conversion CD630_06670 - cdd4 Type: Gene Product:ABC-type transport system,lantibiotic/multidrug-family ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_06650 - cdd2 Type: Gene Product:ABC-type transport system,lantibiotic/multidrug-family permease \| Pathway: \| COG: Function unknown CD630_06690 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_17490 - Type: Gene Product:Putative 2-hydroxyacyl-CoA dehydratase \| Pathway: \| COG: Amino acid transport and metabolism CD630_23080 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_09770 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Function unknown CD630_09750 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_27270 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_09870 - Type: Gene Product:Putative phosphatase/hydrolase \| Pathway: \| COG: Replication, recombination and repair CD630_10040 - fumB Type: Gene Product:Fumarate hydratase class I, subunit B \| Pathway: \| COG: Energy production and conversion CD630_06660 - cdd3 Type: Gene Product:ABC-type transport system,lantibiotic/multidrug-family permease \| Pathway: \| COG: Function unknown CD630_06680 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_27280 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_23070 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_09880 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_09760 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_13920 - Type: Gene Product:Putative endoribonuclease \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_22070 - Type: Gene Product:Putative flavodoxin \| Pathway: \| COG: Function unknown	0.00019	0	0.50	Inferelator: 0 Hypergeometric: 0 TF Influences from Inferelator `No TF influences from Inferelator` TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_268	7 CD630_22951 - Type: Gene Product:Fragment of putative cell surface protein(C-terminal region) \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_31561 - Type: Gene Product:Fragment of conserved hypothetical protein (Part2) \| Pathway: \| COG: Function unknown, Function unknown CD630_06030 - Type: Gene Product:Fragment of putative membrane protein (C-terminalregion) \| Pathway: \| COG: CD630_08460 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_20071 - Type: Gene Product:Fragment of conserved hypothetical protein(N-terminal region) \| Pathway: \| COG: Transcription CD630_27850 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_06020 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG:	`NA`	`NA`	0.50	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_20450 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_68	4 CD630_12910 - dacF Type: Gene Product:D-alanyl-D-alanine carboxypeptidase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_12900 - Type: Gene Product:Putative small acid-soluble spore protein SASP \| Pathway: \| COG: CD630_07080 - pepD Type: Gene Product:Peptidase D, aminoacyl-histidine dipeptidase \| Pathway: \| COG: Amino acid transport and metabolism CD630_32220 - sdaB Type: Gene Product:L-serine dehydratase \| Pathway: \| COG: Amino acid transport and metabolism	`NA`	`NA`	0.50	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_06290 - Type: Gene Product:Transcriptional regulator, Crp family \| Pathway: \| COG: Transcription CD630_25990 - Type: Gene Product:Putative transcriptional regulator \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_150	24 CD630_30440 - Type: Gene Product:Transcriptional regulator, RpiR family \| Pathway: \| COG: Transcription CD630_12090 - recN Type: Gene Product:DNA repair protein RecN (Recombination proteinN) \| Pathway: \| COG: Replication, recombination and repair CD630_33741 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn7-Orf9 \| Pathway: \| COG: Function unknown CD630_33740 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn7-Orf8 \| Pathway: \| COG: Function unknown CD630_33760 - Type: Gene Product:Putative transcriptional regulator Tn916-like,CTn7-Orf11 \| Pathway: \| COG: Transcription CD630_12010 - nusB Type: Gene Product:N utilization substance protein B homolog(Protein NusB) \| Pathway: \| COG: Transcription CD630_12050 - ispA Type: Gene Product:Geranyltranstransferase \| Pathway: \| COG: Coenzyme transport and metabolism CD630_12030 - xseA Type: Gene Product:Exodeoxyribonuclease 7 large subunit \| Pathway: \| COG: Replication, recombination and repair CD630_12070 - dxs Type: Gene Product:1-deoxy-D-xylulose-5-phosphate synthase \| Pathway: Metabolic intermediate biosynthesis \| COG: Coenzyme transport and metabolism CD630_33750 - mgtC Type: Gene Product:Magnesium-transporting ATPase protein C;Tn916-like, CTn7-Orf10 \| Pathway: \| COG: Function unknown CD630_30450 - Type: Gene Product:Putative ATPase, BadF/BadG/BcrA/BcrD type \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_33730 - mgtA Type: Gene Product:Magnesium-transporting ATPase, P-type 1;Tn916-like, CTn7-Orf7 \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_03310 - ppiB Type: Gene Product:Peptidyl-prolyl cis-trans isomerase B (PPIase B)(Rotamase B) \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_12080 - Type: Gene Product:Putative RNA-binding S4-domain protein \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_33770 - mgtA Type: Gene Product:Magnesium-transporting ATPase, P-type 1;Tn916-like, CTn7-Orf12 \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_30510 - anmK Type: Gene Product:Anhydro-N-acetylmuramic acid kinase (AnhMurNAckinase) \| Pathway: Amino-sugar metabolism \| COG: Posttranslational modification, protein turnover, chaperones CD630_30500 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_03290 - Type: Gene Product:Putative aminopeptidase I, M18 family \| Pathway: \| COG: Amino acid transport and metabolism CD630_12000 - Type: Gene Product:Conserved hypothetical protein, DUF322 familly \| Pathway: \| COG: Function unknown CD630_12020 - gcp Type: Gene Product:O-sialoglycoprotein endopeptidase, peptidase M22family \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_12060 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_12040 - xseB Type: Gene Product:Exodeoxyribonuclease VII small subunit \| Pathway: \| COG: Replication, recombination and repair CD630_33780 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn7-Orf13 \| Pathway: \| COG: Energy production and conversion CD630_03300 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown	3.6	`NA`	0.50	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_32800 - Type: Gene Product:Sigma-54 dpendent regulator, PTS fructose family \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_23	16 CD630_22950 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_20930 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Defense mechanisms CD630_t0830 - tRNA-Thr Type: Gene Product: \| Pathway: \| COG: CD630_22930 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_00130 - Type: Gene Product:Putative mechanosensitive ion channel protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_00120 - Type: Gene Product:Putative small-molecule-binding protein \| Pathway: \| COG: Transcription CD630_20970 - Type: Gene Product:Putative membrane protein, DUF988 family \| Pathway: \| COG: Function unknown CD630_17070 - Type: Gene Product:Putative C4-dicarboxylate anaerobic carrier, DcuCfamily \| Pathway: \| COG: Function unknown CD630_11710 - etfB Type: Gene Product:Electron transfer flavoprotein subunit alpha \| Pathway: \| COG: Energy production and conversion CD630_22920 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_20950 - Type: Gene Product:Putative cell division GTPase \| Pathway: \| COG: CD630_13360 - Type: Gene Product:PTS system, glucose-like IIBC component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_20940 - Type: Gene Product:Putative restriction enzyme \| Pathway: \| COG: Defense mechanisms CD630_20960 - Type: Gene Product:Putative DNA-binding protein \| Pathway: \| COG: Transcription CD630_22910 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_22900 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription	0.01	`NA`	0.50	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_34990 - spoVT Type: Gene Product:Stage V sporulation protein T \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`