Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 171 - 180 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

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Title Gene Count Motif 1 e-value Motif 2 e-value Residual Expression TF Influences
Module_397 27
  • CD630_10660 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_03040 - Type: Gene
    Product:Conserved hypothetical protein, DUF1355 family | Pathway: | COG: Function unknown
  • CD630_35190 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_07610 - Type: Gene
    Product:Putative ATP-dependent RNA helicase | Pathway: | COG: Replication, recombination and repair
  • CD630_31840 - dpaL Type: Gene
    Product:Diaminopropionate ammonia-lyase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_34620 - Type: Gene
    Product:Putative antitoxin EndoAI | Pathway: | COG: Transcription
  • CD630_01200 - glmS Type: Gene
    Product:Glucosamine--fructose-6-phosphateaminotransferase [isomerizing] | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_34640 - GerS Type: Gene
    Product:Lipoprotein regulator, germination | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_34660 - acpS Type: Gene
    Product:Holo-[acyl-carrier-protein] synthase | Pathway: | COG: Lipid transport and metabolism
  • CD630_03110 - GerG Type: Gene
    Product:Germination regulator | Pathway: | COG:
  • CD630_10650 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_03030 - argE Type: Gene
    Product:Acetylornithine deacetylase ArgE | Pathway: | COG: Amino acid transport and metabolism
  • CD630_06600 - tcdB Type: Gene
    Product:Toxin B | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_35200 - Type: Gene
    Product:Putative cation efflux protein | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_31790 - pyrD Type: Gene
    Product:Dihydroorotate dehydrogenase, catalytic subunit | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_07600 - Type: Gene
    Product:Putative Ca2+/Na+ antiporter | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_34630 - alr2 Type: Gene
    Product:Alanine racemase 2 | Pathway: Amino-acid biosynthesis | COG: Cell wall/membrane/envelope biogenesis
  • CD630_25621 - rpmB Type: Gene
    Product:50S ribosomal protein L28 | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_31830 - Type: Gene
    Product:Putative peptidase, M20 family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_34610 - EndoA Type: Gene
    Product:Endoribonuclease toxin | Pathway: | COG: Signal transduction mechanisms
  • CD630_31810 - Type: Gene
    Product:Putative amidohydrolase | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_03320 - bclA1 Type: Gene
    Product:Exosporium glycoprotein | Pathway: | COG: Intracellular trafficking, secretion, and vesicular transport, Extracellular structures
  • CD630_34650 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
0.00046 0.02 0.49 Inferelator: 2
Hypergeometric: 2

TF Influences from Inferelator

  1. CD630_06290 - Type: Gene
    Product:Transcriptional regulator, Crp family | Pathway: | COG: Transcription
  2. CD630_34990 - spoVT Type: Gene
    Product:Stage V sporulation protein T | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

  1. CD630_12140 - spo0A Type: Gene
    Product:Stage 0 sporulation protein A | Pathway: | COG: Signal transduction mechanisms
  2. CD630_26430 - sigE Type: Gene
    Product:RNA polymerase sigma-E factor | Pathway: | COG: Transcription
Module_224 26
  • CD630_20790 - xdhA Type: Gene
    Product:Xanthine dehydrogenase, molybdenum bindingsubunit | Pathway: | COG: Energy production and conversion
  • CD630_27340 - Type: Gene
    Product:Putative Na+/H+ antiporter, NhaC family | Pathway: | COG: Energy production and conversion
  • CD630_31610 - Type: Gene
    Product:ABC-type transport system, multidrug-familypermease | Pathway: | COG: Function unknown
  • CD630_20770 - pyrD Type: Gene
    Product:Dihydroorotate dehydrogenase, catalytic subunit | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_20820 - Type: Gene
    Product:Amidohydrolase | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_19560 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_20800 - Type: Gene
    Product:Putative FAD-binding subunit of xanthinedehydrogenase | Pathway: | COG: Energy production and conversion
  • CD630_19540 - Type: Gene
    Product:ABC-type transport system, permease | Pathway: | COG: Defense mechanisms
  • CD630_16690 - Type: Gene
    Product:ABC-type transport system, multidrug-familyATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_23170 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_16730 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_16710 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  • CD630_31620 - Type: Gene
    Product:ABC-type transport system, multidrug-familyATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_20780 - Type: Gene
    Product:Putative S-adenosylhomocysteine deaminase | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_31600 - Type: Gene
    Product:ABC-type transport system, multidrug-familypermease | Pathway: | COG: Function unknown
  • CD630_27330 - Type: Gene
    Product:Putative pyridoxal phosphate-dependenttransferase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_36230 - Type: Gene
    Product:ABC-type transport system, ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_20830 - Type: Gene
    Product:D-hydantoinase (Dihydropyrimidinase) | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_19550 - Type: Gene
    Product:ABC-type transport system, ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_19570 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  • CD630_20810 - xdhC1 Type: Gene
    Product:Xanthine dehydrogenase iron-sulfur bindingsubunit XdhC1 | Pathway: | COG: Energy production and conversion
  • CD630_16680 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG:
  • CD630_23160 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  • CD630_16700 - Type: Gene
    Product:ABC-type transport system, multidrug-familypermease | Pathway: | COG:
  • CD630_16720 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_36240 - Type: Gene
    Product:ABC-type transport system, permease | Pathway: | COG: Function unknown
0.17 NA 0.49 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_02760 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription
  2. CD630_32140 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_145 21
  • CD630_20900 - Type: Gene
    Product:Putative xanthine/uracile permease | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_17540 - Type: Gene
    Product:ABC-type transport system, multidrug-familypermease | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_20870 - Type: Gene
    Product:Putative xanthine dehydrogenase | Pathway: | COG: Energy production and conversion
  • CD630_22590 - Type: Gene
    Product:Conserved hypothetical protein with RmlC-likejelly roll fold | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_17520 - Type: Gene
    Product:Transcriptional regulator, TetR family | Pathway: | COG: Transcription
  • CD630_22580 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_20990 - XdhD Type: Gene
    Product:Xanthine dehydrogenase subunit XdhD,molybdopterin-binding | Pathway: | COG: Energy production and conversion
  • CD630_17530 - Type: Gene
    Product:ABC-type transport system, multidrug-familyATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_15610 - Type: Gene
    Product:Putative dehydrogenase | Pathway: | COG: Posttranslational modification, protein turnover, chaperones
  • CD630_17570 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_20880 - xdhC2 Type: Gene
    Product:Xanthine dehydrogenase iron-sulfur bindingsubunit XdhC2 | Pathway: | COG: Energy production and conversion
  • CD630_20730 - xdhA Type: Gene
    Product:Xanthine dehydrogenase, molybdenum bindingsubunit | Pathway: | COG: Energy production and conversion
  • CD630_20890 - Type: Gene
    Product:Putative metal-dependent hydrolase | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_17550 - Type: Gene
    Product:ABC-type transport system, multidrug-familypermease | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_17551 - Type: Gene
    Product:Transcriptional regulator, HTH-type | Pathway: | COG: Transcription
  • CD630_20860 - Type: Gene
    Product:Putative NAD(P)H-dependent FMN reductase | Pathway: | COG: Function unknown
  • CD630_21000 - XdhC3 Type: Gene
    Product:Xanthine dehydrogenase iron-sulfur bindingsubunit XdhC3 | Pathway: | COG: Energy production and conversion
  • CD630_21010 - xdhB Type: Gene
    Product:Xanthine dehydrogenase subunit XdhB, FAD-binding | Pathway: | COG: Energy production and conversion
  • CD630_17560 - def1 Type: Gene
    Product:Peptide deformylase 1 (PDF 1) (Polypeptidedeformylase 1) | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_20740 - Type: Gene
    Product:Putative FAD-binding subunit of xanthinedehydrogenase | Pathway: | COG: Energy production and conversion
  • CD630_17580 - Type: Gene
    Product:Putative radical SAM superfamily protein | Pathway: | COG: Replication, recombination and repair
0 NA 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_17820 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_273 17
  • CD630_02050 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_02070 - Type: Gene
    Product:PTS system, fructose-like IIC component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_31760 - glnF Type: Gene
    Product:RNA polymerase sigma-54 factor | Pathway: | COG: Transcription
  • CD630_01200 - glmS Type: Gene
    Product:Glucosamine--fructose-6-phosphateaminotransferase [isomerizing] | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_02090 - Type: Gene
    Product:Putative tagatose 6-phosphate kinase | Pathway: | COG: Function unknown
  • CD630_24400 - Type: Gene
    Product:Putative metal-dependent hydrolase | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_24360 - Type: Gene
    Product:Putative divalent cation transporter, MgtEfamily | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_35980 - luxS Type: Gene
    Product:S-ribosylhomocysteine lyase (Autoinducer-2production protein luxS) (AI-2 synthesis protein) | Pathway: | COG: Signal transduction mechanisms
  • CD630_03120 - Type: Gene
    Product:Transcriptional regulator, ArsR family | Pathway: | COG: Transcription
  • CD630_24370 - era Type: Gene
    Product:GTP-binding protein Era | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_03130 - Type: Gene
    Product:Putative K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transportingP-type ATPase | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_24390 - Type: Gene
    Product:Putative diacylglycerol kinase | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_02080 - Type: Gene
    Product:PTS system, fructose-like IIB component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_35970 - Type: Gene
    Product:Putative S-adenosyl-L-methionine dependentmethionine synthase | Pathway: | COG: Function unknown
  • CD630_24380 - cdd Type: Gene
    Product:Cytidine deaminase (Cytidine aminohydrolase)(CDA) | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_02060 - Type: Gene
    Product:PTS system, fructose-like IIA component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_35960 - Type: Gene
    Product:putative homocysteine S-methyltransferase | Pathway: | COG: Amino acid transport and metabolism
0.08 NA 0.49 Inferelator: 3
Hypergeometric: 1

TF Influences from Inferelator

  1. CD630_22140 - SinR Type: Gene
    Product:Transcriptional regulator, HTH-type | Pathway: | COG: Transcription
  2. CD630_26400 - nrdR Type: Gene
    Product:Transcriptional regulator, repressor NrdR family | Pathway: | COG: Transcription
  3. CD630_34990 - spoVT Type: Gene
    Product:Stage V sporulation protein T | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

  1. CD630_02660 - sigD Type: Gene
    Product:RNA polymerase sigma-28 factor for flagellaroperon | Pathway: | COG: Transcription
Module_354 10
  • CD630_05250 - Type: Gene
    Product:Fragment of aminobenzoyl-glutamate transporter(Part 2) | Pathway: | COG: Coenzyme transport and metabolism, Coenzyme transport and metabolism
  • CD630_02760 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription
  • CD630_11860 - Type: Gene
    Product:Transcriptional regulator, sigma-54-dependent | Pathway: | COG: Transcription
  • CD630_33680 - Type: Gene
    Product:Putative ribosome biogenesis GTPase RsgA;putative EngC-like GTPase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_30040 - kdgT2 Type: Gene
    Product:2-keto-3-deoxygluconate permease 2 | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_06450 - Type: Gene
    Product:ABC-type transport system,lantibiotic/multidrug-family ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_30030 - Type: Gene
    Product:Putative N-terminus region of carbohydratehydrolase, SAF domain | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_01111 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_05081 - Type: Gene
    Product:Putative conjugative transposon protein Tn5397,CTn3-Orf6 | Pathway: | COG: Function unknown
  • CD630_33681 - Type: Gene
    Product:Putative zinc finger protein | Pathway: | COG: Function unknown
0.55 NA 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_03200 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_36 23
  • CD630_20350 - Type: Gene
    Product:Putative sporulation integral membrane protein | Pathway: | COG: Function unknown
  • CD630_24220 - Type: Gene
    Product:Sodium:alanine symporter | Pathway: | COG: Amino acid transport and metabolism
  • CD630_18200 - ade Type: Gene
    Product:Adenine deaminase (Disrupted IStron) | Pathway: | COG: Nucleotide transport and metabolism, Nucleotide transport and metabolism
  • CD630_20390 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_t0640 - tRNA-Met Type: Gene
    Product: | Pathway: | COG:
  • CD630_24210 - Type: Gene
    Product:Putative amidohydrolase, M20D family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_t0150 - tRNA-Ser Type: Gene
    Product: | Pathway: | COG:
  • CD630_t0850 - tRNA-Val Type: Gene
    Product: | Pathway: | COG:
  • CD630_t0870 - tRNA-Lys Type: Gene
    Product: | Pathway: | COG:
  • CD630_21151 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_20360 - Type: Gene
    Product:Putative peptidylarginine deiminase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_t0440 - tRNA-Arg Type: Gene
    Product: | Pathway: | COG:
  • CD630_19942 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_t0560 - tRNA-Lys Type: Gene
    Product: | Pathway: | COG:
  • CD630_20380 - Type: Gene
    Product:Putative drug/sodium antiporter, MATE family | Pathway: | COG: Defense mechanisms
  • CD630_24200 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_t0040 - tRNA-Leu Type: Gene
    Product: | Pathway: | COG:
  • CD630_34570 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_18910 - Type: Gene
    Product:Fragment of ABC-type transport system,substrate-binding protein (Part 2) | Pathway: | COG: Inorganic ion transport and metabolism, Inorganic ion transport and metabolism
  • CD630_31930 - Type: Gene
    Product:Putative phage-related protein | Pathway: | COG: Function unknown
  • CD630_31691 - secG Type: Gene
    Product:Protein-export membrane protein SecG | Pathway: | COG: Intracellular trafficking, secretion, and vesicular transport
  • CD630_31630 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_20370 - Type: Gene
    Product:Putative acyl-CoA acyltransferase | Pathway: | COG: Function unknown
1.3e-22 2.5e-19 0.49 Inferelator: 3
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_26400 - nrdR Type: Gene
    Product:Transcriptional regulator, repressor NrdR family | Pathway: | COG: Transcription
  2. CD630_26430 - sigE Type: Gene
    Product:RNA polymerase sigma-E factor | Pathway: | COG: Transcription
  3. CD630_34990 - spoVT Type: Gene
    Product:Stage V sporulation protein T | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_52 14
  • CD630_t0230 - tRNA-Asn Type: Gene
    Product: | Pathway: | COG:
  • CD630_15570 - Type: Gene
    Product:Putative peptidylprolyl isomerase | Pathway: | COG: Posttranslational modification, protein turnover, chaperones
  • CD630_15600 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_15560 - Type: Gene
    Product:Putative polysaccharide deacetylase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_15590 - rsiV Type: Gene
    Product:Anti Sigma Factor, ECF family | Pathway: | COG: Function unknown
  • CD630_30550 - Type: Gene
    Product:ABC-type transport system, permease | Pathway: | COG: Defense mechanisms
  • CD630_20101 - ermC Type: Gene
    Product:23S rRNA methylase leader peptide | Pathway: | COG:
  • CD630_12040 - xseB Type: Gene
    Product:Exodeoxyribonuclease VII small subunit | Pathway: | COG: Replication, recombination and repair
  • CD630_11240 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_15580 - sigV Type: Gene
    Product:Extra-Cytoplasmic Function sigma factors, ECFfamily | Pathway: | COG: Transcription
  • CD630_17620 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_15620 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_30560 - Type: Gene
    Product:ABC-type transport system, ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_06700 - Type: Gene
    Product:Transcriptional regulator, beta-lactamsrepressor | Pathway: | COG: Transcription
0.54 NA 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_06700 - Type: Gene
    Product:Transcriptional regulator, beta-lactamsrepressor | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_355 17
  • CD630_18490 - Type: Gene
    Product:Putative conjugative transfer proteinTn1549-like, CTn5-Orf5 | Pathway: | COG: Intracellular trafficking, secretion, and vesicular transport
  • CD630_03850 - Type: Gene
    Product:Putative conjugative transposon protein DUF961family Tn916-like, CTn1-Orf30 | Pathway: | COG: Function unknown
  • CD630_18480 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf4 | Pathway: | COG: Function unknown
  • CD630_03860 - Type: Gene
    Product:Putative cell surface protein | Pathway: | COG: Function unknown
  • CD630_33420 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf19 | Pathway: | COG: Function unknown
  • CD630_33920 - Type: Gene
    Product:Putative cell surface protein | Pathway: | COG: Function unknown
  • CD630_18460 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf2 | Pathway: | COG: Function unknown
  • CD630_33890 - Type: Gene
    Product:Putative cell-division FtsK/SpoIIIE-familyprotein Tn916-like, CTn7-Orf28 | Pathway: | COG: Cell cycle control, cell division, chromosome partitioning
  • CD630_22810 - Type: Gene
    Product:PTS system, fructose/mannitol family IIBcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_18470 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf3 | Pathway: | COG: Function unknown
  • CD630_03820 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn1-Orf27 | Pathway: | COG:
  • CD630_03840 - Type: Gene
    Product:Putative conjugative transposon protein DUF961family Tn916-like, CTn1-Orf29 | Pathway: | COG: Function unknown
  • CD630_18450 - Type: Gene
    Product:Putative membrane protein Tn1549-like, CTn5-Orf1 | Pathway: | COG: Function unknown
  • CD630_03830 - Type: Gene
    Product:Putative cell-division FtsK/SpoIIIE-familyprotein Tn916-like, CTn1-Orf28 | Pathway: | COG: Cell cycle control, cell division, chromosome partitioning
  • CD630_33900 - Type: Gene
    Product:Putative conjugative transposon protein DUF961family Tn196-like, CTn7-Orf29 | Pathway: | COG: Function unknown
  • CD630_33910 - Type: Gene
    Product:Putative conjugative transposon protein DUF961family Tn916-like, CTn7-Orf30 | Pathway: | COG: Function unknown
  • CD630_03851 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
0.00045 10 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_34990 - spoVT Type: Gene
    Product:Stage V sporulation protein T | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_134 19
  • CD630_31320 - Type: Gene
    Product:PTS system, fructose-like IIA component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_03350 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_36300 - Type: Gene
    Product:PTS system, fructose/mannitol-family IIBcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_03370 - Type: Gene
    Product:ABC-type transport system, permease | Pathway: | COG: Defense mechanisms
  • CD630_36260 - Type: Gene
    Product:Putative 4-hydroxy-2-oxoglutarate aldolase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25520 - Type: Gene
    Product:Putative phosphosugar isomerase | Pathway: | COG: Function unknown
  • CD630_17350 - Type: Gene
    Product:Putative hydrolase | Pathway: | COG: Function unknown
  • CD630_36310 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_31310 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription
  • CD630_17370 - Type: Gene
    Product:Putative divalent ion symporter | Pathway: | COG: Amino acid transport and metabolism, Carbohydrate transport and metabolism
  • CD630_25530 - Type: Gene
    Product:PTS system, fructose/mannitol-family IICcomponent (Disrupted IStron) | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_17360 - Type: Gene
    Product:Transcriptional regulator, HTH-type | Pathway: | COG: Transcription
  • CD630_03380 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_25510 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_03390 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  • CD630_31330 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_17380 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_03360 - Type: Gene
    Product:ABC-type transport system, ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_17390 - Type: Gene
    Product:Two-component response regulator, sigma-54dependent regulator | Pathway: | COG: Signal transduction mechanisms
0.000017 NA 0.49 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_03390 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  2. CD630_30770 - Type: Gene
    Product:Transcriptional regulator, RpiR family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_87 7
  • CD630_35871 - Type: Gene
    Product:Fragment of putative transposase (N-terminalregion) | Pathway: | COG:
  • CD630_35940 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Energy production and conversion
  • CD630_00030 - Type: Gene
    Product:Putative RNA-binding mediating protein | Pathway: | COG: Function unknown
  • CD630_20990 - XdhD Type: Gene
    Product:Xanthine dehydrogenase subunit XdhD,molybdopterin-binding | Pathway: | COG: Energy production and conversion
  • CD630_35930 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_21010 - xdhB Type: Gene
    Product:Xanthine dehydrogenase subunit XdhB, FAD-binding | Pathway: | COG: Energy production and conversion
  • CD630_21000 - XdhC3 Type: Gene
    Product:Xanthine dehydrogenase iron-sulfur bindingsubunit XdhC3 | Pathway: | COG: Energy production and conversion
NA NA 0.49 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_06480 - Type: Gene
    Product:Transcriptional regulator, GntR family | Pathway: | COG: Transcription
  2. CD630_35830 - Type: Gene
    Product:Transcriptional regulator, MerR family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test