Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 171 - 180 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Title	Gene Count	Motif 1 e-value	Motif 2 e-value	Residual	TF Influences
Module_87	7 CD630_35871 - Type: Gene Product:Fragment of putative transposase (N-terminalregion) \| Pathway: \| COG: CD630_35940 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Energy production and conversion CD630_00030 - Type: Gene Product:Putative RNA-binding mediating protein \| Pathway: \| COG: Function unknown CD630_20990 - XdhD Type: Gene Product:Xanthine dehydrogenase subunit XdhD,molybdopterin-binding \| Pathway: \| COG: Energy production and conversion CD630_35930 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_21010 - xdhB Type: Gene Product:Xanthine dehydrogenase subunit XdhB, FAD-binding \| Pathway: \| COG: Energy production and conversion CD630_21000 - XdhC3 Type: Gene Product:Xanthine dehydrogenase iron-sulfur bindingsubunit XdhC3 \| Pathway: \| COG: Energy production and conversion	`NA`	`NA`	0.49	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_06480 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_35830 - Type: Gene Product:Transcriptional regulator, MerR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_224	26 CD630_20790 - xdhA Type: Gene Product:Xanthine dehydrogenase, molybdenum bindingsubunit \| Pathway: \| COG: Energy production and conversion CD630_27340 - Type: Gene Product:Putative Na+/H+ antiporter, NhaC family \| Pathway: \| COG: Energy production and conversion CD630_31610 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Function unknown CD630_20770 - pyrD Type: Gene Product:Dihydroorotate dehydrogenase, catalytic subunit \| Pathway: \| COG: Nucleotide transport and metabolism CD630_20820 - Type: Gene Product:Amidohydrolase \| Pathway: \| COG: Nucleotide transport and metabolism CD630_19560 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_20800 - Type: Gene Product:Putative FAD-binding subunit of xanthinedehydrogenase \| Pathway: \| COG: Energy production and conversion CD630_19540 - Type: Gene Product:ABC-type transport system, permease \| Pathway: \| COG: Defense mechanisms CD630_16690 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_23170 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_16730 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_16710 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_31620 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_20780 - Type: Gene Product:Putative S-adenosylhomocysteine deaminase \| Pathway: \| COG: Nucleotide transport and metabolism CD630_31600 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Function unknown CD630_27330 - Type: Gene Product:Putative pyridoxal phosphate-dependenttransferase \| Pathway: \| COG: Amino acid transport and metabolism CD630_36230 - Type: Gene Product:ABC-type transport system, ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_20830 - Type: Gene Product:D-hydantoinase (Dihydropyrimidinase) \| Pathway: \| COG: Nucleotide transport and metabolism CD630_19550 - Type: Gene Product:ABC-type transport system, ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_19570 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_20810 - xdhC1 Type: Gene Product:Xanthine dehydrogenase iron-sulfur bindingsubunit XdhC1 \| Pathway: \| COG: Energy production and conversion CD630_16680 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_23160 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_16700 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: CD630_16720 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_36240 - Type: Gene Product:ABC-type transport system, permease \| Pathway: \| COG: Function unknown	0.17	`NA`	0.49	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_02760 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_32140 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_40	19 CD630_11041 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf18 \| Pathway: \| COG: Function unknown CD630_11042 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf17 \| Pathway: \| COG: Function unknown CD630_11050 - Type: Gene Product:Putative antirestriction protein Tn1549-like,CTn4-Orf16 \| Pathway: \| COG: Function unknown CD630_11071 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf12 \| Pathway: \| COG: Function unknown CD630_11070 - Type: Gene Product:Putative cell surface protein Tn1549-like,CTn4-Orf13 \| Pathway: \| COG: Function unknown CD630_11061 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf14 \| Pathway: \| COG: Function unknown CD630_33400 - Type: Gene Product:Putative antirestriction protein Tn916-like,CTn6-Orf17 \| Pathway: \| COG: Function unknown CD630_33360 - Type: Gene Product:Putative cell wall hydrolase Tn916-like,CTn6-Orf13 \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_33280 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf4 \| Pathway: \| COG: Function unknown CD630_11120 - Type: Gene Product:Putative membrane protein Tn1549-like, CTn4-Orf7 \| Pathway: \| COG: Function unknown CD630_11080 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf11 \| Pathway: \| COG: Function unknown CD630_33370 - Type: Gene Product:Putative membrane protein Tn916-like, CTn6-Orf14 \| Pathway: \| COG: Function unknown CD630_11090 - Type: Gene Product:DNA-methyltransferase, cytosine-N4-specific;Tn1549-like, CTn4-Orf10 \| Pathway: \| COG: Replication, recombination and repair CD630_33390 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf16 \| Pathway: \| COG: Function unknown CD630_11060 - topB Type: Gene Product:DNA topoisomerase III; Tn1549-like, CTn4-Orf15 \| Pathway: \| COG: Replication, recombination and repair CD630_33380 - Type: Gene Product:Putative ATPase Tn916-like, CTn6-Orf15 \| Pathway: \| COG: Function unknown CD630_33350 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf12 \| Pathway: \| COG: Function unknown CD630_11110 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf8 \| Pathway: \| COG: Function unknown CD630_11100 - Type: Gene Product:Putative hydrolase Tn1549-like, CTn4-Orf9 \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport	0.00028	2.7	0.49	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_01710 - rex Type: Gene Product:Transcriptional regulator, Redox-sensingrepressor Rex \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_273	17 CD630_02050 - Type: Gene Product:Transcription antiterminator, PTS operonregulator \| Pathway: \| COG: Transcription CD630_02070 - Type: Gene Product:PTS system, fructose-like IIC component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_31760 - glnF Type: Gene Product:RNA polymerase sigma-54 factor \| Pathway: \| COG: Transcription CD630_01200 - glmS Type: Gene Product:Glucosamine--fructose-6-phosphateaminotransferase [isomerizing] \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_02090 - Type: Gene Product:Putative tagatose 6-phosphate kinase \| Pathway: \| COG: Function unknown CD630_24400 - Type: Gene Product:Putative metal-dependent hydrolase \| Pathway: \| COG: Nucleotide transport and metabolism CD630_24360 - Type: Gene Product:Putative divalent cation transporter, MgtEfamily \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_35980 - luxS Type: Gene Product:S-ribosylhomocysteine lyase (Autoinducer-2production protein luxS) (AI-2 synthesis protein) \| Pathway: \| COG: Signal transduction mechanisms CD630_03120 - Type: Gene Product:Transcriptional regulator, ArsR family \| Pathway: \| COG: Transcription CD630_24370 - era Type: Gene Product:GTP-binding protein Era \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_03130 - Type: Gene Product:Putative K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transportingP-type ATPase \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_24390 - Type: Gene Product:Putative diacylglycerol kinase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_02080 - Type: Gene Product:PTS system, fructose-like IIB component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_35970 - Type: Gene Product:Putative S-adenosyl-L-methionine dependentmethionine synthase \| Pathway: \| COG: Function unknown CD630_24380 - cdd Type: Gene Product:Cytidine deaminase (Cytidine aminohydrolase)(CDA) \| Pathway: \| COG: Nucleotide transport and metabolism CD630_02060 - Type: Gene Product:PTS system, fructose-like IIA component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_35960 - Type: Gene Product:putative homocysteine S-methyltransferase \| Pathway: \| COG: Amino acid transport and metabolism	0.08	`NA`	0.49	Inferelator: 3 Hypergeometric: 1 TF Influences from Inferelator CD630_22140 - SinR Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_26400 - nrdR Type: Gene Product:Transcriptional regulator, repressor NrdR family \| Pathway: \| COG: Transcription CD630_34990 - spoVT Type: Gene Product:Stage V sporulation protein T \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test CD630_02660 - sigD Type: Gene Product:RNA polymerase sigma-28 factor for flagellaroperon \| Pathway: \| COG: Transcription
Module_26	6 CD630_07570 - Type: Gene Product:Phosphodiesterases protein \| Pathway: \| COG: Signal transduction mechanisms CD630_18311 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_20160 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_18430 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_10150 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms	`NA`	`NA`	0.49	Inferelator: 0 Hypergeometric: 0 TF Influences from Inferelator `No TF influences from Inferelator` TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_354	10 CD630_05250 - Type: Gene Product:Fragment of aminobenzoyl-glutamate transporter(Part 2) \| Pathway: \| COG: Coenzyme transport and metabolism, Coenzyme transport and metabolism CD630_02760 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_11860 - Type: Gene Product:Transcriptional regulator, sigma-54-dependent \| Pathway: \| COG: Transcription CD630_33680 - Type: Gene Product:Putative ribosome biogenesis GTPase RsgA;putative EngC-like GTPase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_30040 - kdgT2 Type: Gene Product:2-keto-3-deoxygluconate permease 2 \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_06450 - Type: Gene Product:ABC-type transport system,lantibiotic/multidrug-family ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_30030 - Type: Gene Product:Putative N-terminus region of carbohydratehydrolase, SAF domain \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_01111 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_05081 - Type: Gene Product:Putative conjugative transposon protein Tn5397,CTn3-Orf6 \| Pathway: \| COG: Function unknown CD630_33681 - Type: Gene Product:Putative zinc finger protein \| Pathway: \| COG: Function unknown	0.55	`NA`	0.49	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_03200 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_355	17 CD630_18490 - Type: Gene Product:Putative conjugative transfer proteinTn1549-like, CTn5-Orf5 \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_03850 - Type: Gene Product:Putative conjugative transposon protein DUF961family Tn916-like, CTn1-Orf30 \| Pathway: \| COG: Function unknown CD630_18480 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf4 \| Pathway: \| COG: Function unknown CD630_03860 - Type: Gene Product:Putative cell surface protein \| Pathway: \| COG: Function unknown CD630_33420 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf19 \| Pathway: \| COG: Function unknown CD630_33920 - Type: Gene Product:Putative cell surface protein \| Pathway: \| COG: Function unknown CD630_18460 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf2 \| Pathway: \| COG: Function unknown CD630_33890 - Type: Gene Product:Putative cell-division FtsK/SpoIIIE-familyprotein Tn916-like, CTn7-Orf28 \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_22810 - Type: Gene Product:PTS system, fructose/mannitol family IIBcomponent \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_18470 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf3 \| Pathway: \| COG: Function unknown CD630_03820 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn1-Orf27 \| Pathway: \| COG: CD630_03840 - Type: Gene Product:Putative conjugative transposon protein DUF961family Tn916-like, CTn1-Orf29 \| Pathway: \| COG: Function unknown CD630_18450 - Type: Gene Product:Putative membrane protein Tn1549-like, CTn5-Orf1 \| Pathway: \| COG: Function unknown CD630_03830 - Type: Gene Product:Putative cell-division FtsK/SpoIIIE-familyprotein Tn916-like, CTn1-Orf28 \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_33900 - Type: Gene Product:Putative conjugative transposon protein DUF961family Tn196-like, CTn7-Orf29 \| Pathway: \| COG: Function unknown CD630_33910 - Type: Gene Product:Putative conjugative transposon protein DUF961family Tn916-like, CTn7-Orf30 \| Pathway: \| COG: Function unknown CD630_03851 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG:	0.00045	10	0.49	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_34990 - spoVT Type: Gene Product:Stage V sporulation protein T \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_29	15 CD630_10960 - Type: Gene Product:ABC-type transport system, multidrug-familypermease Tn1549-like, CTn4-Orf29 \| Pathway: \| COG: Function unknown CD630_33640 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Function unknown CD630_10970 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein Tn1549-like, CTn4-Orf28 \| Pathway: \| COG: Defense mechanisms CD630_33620 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Function unknown CD630_10950 - Type: Gene Product:ABC-type transport system, multidrug-familypermease Tn1549-like, CTn4-Orf30 \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_33680 - Type: Gene Product:Putative ribosome biogenesis GTPase RsgA;putative EngC-like GTPase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_33630 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG: Function unknown CD630_10991 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf25 \| Pathway: \| COG: Function unknown CD630_10990 - Type: Gene Product:Two-component response regulator, Tn1549-like,CTn4-Orf26 \| Pathway: \| COG: Signal transduction mechanisms CD630_33681 - Type: Gene Product:Putative zinc finger protein \| Pathway: \| COG: Function unknown CD630_10980 - Type: Gene Product:Two-component sensor histidine kinase,Tn1549-like, CTn4-Orf27 \| Pathway: \| COG: Signal transduction mechanisms CD630_03810 - Type: Gene Product:Putative replication initiation factorTn916-like, CTn1-Orf26 \| Pathway: \| COG: Transcription CD630_03790 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn1-Orf24 \| Pathway: \| COG: Function unknown CD630_11000 - Type: Gene Product:Transcriptional regulator, HTH-type Tn1549-like,CTn4-Orf24 \| Pathway: \| COG: Transcription CD630_03800 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn1-Orf25 \| Pathway: \| COG: Function unknown	0.000037	0.000066	0.49	Inferelator: 3 Hypergeometric: 0 TF Influences from Inferelator CD630_02760 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_05310 - Type: Gene Product:Transcriptional regulator, DeoR family \| Pathway: \| COG: Transcription CD630_32800 - Type: Gene Product:Sigma-54 dpendent regulator, PTS fructose family \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_294	26 CD630_10460 - pepT Type: Gene Product:Peptidase T \| Pathway: \| COG: Amino acid transport and metabolism CD630_26450 - Type: Gene Product:ABC-type transport system, sugar-familyextracellular solute-binding protein \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_30330 - trxA Type: Gene Product:Thioredoxin \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_30350 - Type: Gene Product:Putative diaminopimelate epimerase, PhzF family \| Pathway: \| COG: Function unknown CD630_04530 - Type: Gene Product:Putative hydrolase \| Pathway: \| COG: Nucleotide transport and metabolism CD630_04510 - Type: Gene Product:Putative dioxygenase \| Pathway: \| COG: Function unknown CD630_19700 - Type: Gene Product:Putative enzyme, cyclase family \| Pathway: \| COG: Amino acid transport and metabolism CD630_19690 - Type: Gene Product:Putative oligonucleotide binding regulator \| Pathway: \| COG: Function unknown CD630_32810 - proC Type: Gene Product:Pyrroline-5-carboxylate reductase \| Pathway: Amino-acid biosynthesis \| COG: Amino acid transport and metabolism CD630_07140 - Type: Gene Product:Putative protein involved in protein-proteininteractions \| Pathway: \| COG: Function unknown CD630_16290 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_02020 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_06270 - Type: Gene Product:Putative transcriptional regulator, activatorMor \| Pathway: \| COG: CD630_07121 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_17670 - gapB Type: Gene Product:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_26460 - ftsZ Type: Gene Product:Cell division protein FtsZ \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_30340 - Type: Gene Product:Transcriptional regulator, TrmB family \| Pathway: \| COG: Transcription CD630_21150 - Type: Gene Product:Putative copper-transporting P-type ATPase \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_04520 - Type: Gene Product:Putative hydrolase, NUDIX family \| Pathway: \| COG: Nucleotide transport and metabolism CD630_15780 - Type: Gene Product:Putative membrane-associated ribonuclease BN-like(Rbn) \| Pathway: \| COG: Function unknown CD630_10450 - Type: Gene Product:Putative sporulation integral membrane protein \| Pathway: \| COG: Function unknown CD630_19670 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_07150 - ptb Type: Gene Product:Phosphate butyryltransferase(Phosphotransbutyrylase) \| Pathway: \| COG: Energy production and conversion CD630_06260 - Type: Gene Product:Putative replicative helicase DnaB-like \| Pathway: \| COG: Replication, recombination and repair CD630_19680 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_07130 - Type: Gene Product:Putative radical SAM domain-containing protein \| Pathway: \| COG: Energy production and conversion	0.00000012	0.00043	0.49	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_18100 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_265	5 CD630_22600 - Type: Gene Product:Transporter, Major Facilitator Superfamily (MFS) \| Pathway: \| COG: Amino acid transport and metabolism CD630_24220 - Type: Gene Product:Sodium:alanine symporter \| Pathway: \| COG: Amino acid transport and metabolism CD630_12600 - brnQ-2 Type: Gene Product:Branched chain amino acid transport systemcarrier protein \| Pathway: \| COG: Amino acid transport and metabolism CD630_24210 - Type: Gene Product:Putative amidohydrolase, M20D family \| Pathway: \| COG: Amino acid transport and metabolism CD630_31690 - Type: Gene Product:Putative malate transporter \| Pathway: \| COG: Function unknown	3.1	`NA`	0.49	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_10230 - Type: Gene Product:Putative transcriptional regulator, HTH \| Pathway: \| COG: Transcription CD630_15580 - sigV Type: Gene Product:Extra-Cytoplasmic Function sigma factors, ECFfamily \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`