Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 161 - 170 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Filter by Module number e.g "401"
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Title Gene Count Motif 1 e-value Motif 2 e-value Residual Expression TF Influences
Module_356 31
  • CD630_36150 - Type: Gene
    Product:Transcriptional regulator, MerR family | Pathway: | COG: Transcription
  • CD630_32350 - ssb Type: Gene
    Product:Single-stranded DNA-binding protein | Pathway: | COG: Replication, recombination and repair
  • CD630_12440 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_06920 - Type: Gene
    Product:Putative metallo-hydrolase/oxidoreductase | Pathway: | COG: Function unknown
  • CD630_18880 - rsiU Type: Gene
    Product:Anti Sigma Factor, ECF family | Pathway: | COG: Function unknown
  • CD630_01640 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG:
  • CD630_29510 - Type: Gene
    Product:Putative phage protein | Pathway: | COG: Function unknown
  • CD630_10870 - zupT Type: Gene
    Product:Putative zinc/iron transporter, ZupT subfamiliy | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_12420 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_06710 - Type: Gene
    Product:Putative enzyme, glyoxalase family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_20250 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
  • CD630_10850 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
  • CD630_20190 - Type: Gene
    Product:Transporter drug resistance, Major FacilitatorSuperfamily (MFS) | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_18900 - Type: Gene
    Product:ABC-type transport system, multidrug-familypermease | Pathway: | COG: Function unknown
  • CD630_10890 - rgbR Type: Gene
    Product:Two-component response regulator VirR-like | Pathway: | COG: Signal transduction mechanisms
  • CD630_20240 - Type: Gene
    Product:ABC-type transport system, multidrug-familyATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_18840 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_36160 - Type: Gene
    Product:Na(+)/H(+) antiporter | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_33300 - Type: Gene
    Product:Transcriptional regulator, HTH-type Tn916-like,CTn6-Orf6 | Pathway: | COG: Transcription
  • CD630_12380 - Type: Gene
    Product:Putative phage protein | Pathway: | COG:
  • CD630_12450 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_19941 - Type: Gene
    Product:Transcriptional regulator, ArsR family | Pathway: | COG: Transcription
  • CD630_19940 - Type: Gene
    Product:Putative membrane protein, DUF1648 family | Pathway: | COG: Function unknown
  • CD630_12430 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_18890 - Type: Gene
    Product:ABC-type transport system, multidrug-familyATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_10860 - Type: Gene
    Product:Putative peptidase, M20D family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_18830 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription
  • CD630_18870 - csfU Type: Gene
    Product:Extra-Cytoplasmic Function sigma factors, ECFfamily | Pathway: | COG: Transcription
  • CD630_07490 - Type: Gene
    Product:Putative DNA helicase, UvrD/REP type | Pathway: | COG: Replication, recombination and repair
  • CD630_10880 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_20230 - Type: Gene
    Product:Transcriptional regulator, GntR family | Pathway: | COG: Transcription
6.4e-17 NA 0.48 Inferelator: 1
Hypergeometric: 1

TF Influences from Inferelator

  1. CD630_34990 - spoVT Type: Gene
    Product:Stage V sporulation protein T | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

  1. CD630_26430 - sigE Type: Gene
    Product:RNA polymerase sigma-E factor | Pathway: | COG: Transcription
Module_322 20
  • CD630_27720 - tuaG Type: Gene
    Product:Putative glycosyl transferase, family 2 | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_25730 - Type: Gene
    Product:Putative hydrolase, HAD superfamily, subfamilyIA | Pathway: | COG: Function unknown
  • CD630_27600 - Type: Gene
    Product:Putative signaling protein | Pathway: | COG: Signal transduction mechanisms
  • CD630_27710 - rkpK Type: Gene
    Product:UDP-glucose 6-dehydrogenase | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_25720 - Type: Gene
    Product:Putative nitroreductase | Pathway: | COG: Energy production and conversion
  • CD630_03910 - asnB Type: Gene
    Product:Asparagine synthetase [glutamine-hydrolyzing] | Pathway: | COG: Amino acid transport and metabolism
  • CD630_27650 - LcpA Type: Gene
    Product:Surface-anchoring factors, LytR-CpsA-Psr-likeprotein | Pathway: | COG: Transcription
  • CD630_27740 - Type: Gene
    Product:Putative glycosyl transferase, family 2 | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_13960 - Type: Gene
    Product:Putative amino acid amidase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_27800 - pgm Type: Gene
    Product:Alpha-phosphoglucomutase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_27750 - Type: Gene
    Product:Putative glycerophosphotransferase | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_27810 - mviN Type: Gene
    Product:Cell well glycopolymers exporter, flipase-type | Pathway: Cell wall biogenesis | COG: Signal transduction mechanisms
  • CD630_27730 - Type: Gene
    Product:Putative glycosyl transferase, family 2 | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_17510 - cwp13 Type: Gene
    Product:Cell surface protein | Pathway: | COG: Posttranslational modification, protein turnover, chaperones
  • CD630_27670 - cwp19 Type: Gene
    Product:Cell surface protein | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_27690 - Type: Gene
    Product:Putative polysaccharide biosynthesis protein | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_01730 - Type: Gene
    Product:Putative lipoprotein | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_27760 - Type: Gene
    Product:Putative glycosyl transferase, family 2 | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_27790 - manC Type: Gene
    Product:Putative mannose-1-phosphate guanylyltransferase | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_27770 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
0.06 NA 0.48 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_17820 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_163 25
  • CD630_18840 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_27540 - Type: Gene
    Product:Putative diguanylate kinase signaling protein | Pathway: | COG: Signal transduction mechanisms
  • CD630_21991 - Type: Gene
    Product:Putative 4Fe-4S ferredoxin iron-sulfur bindingdomain-containing protein | Pathway: | COG: Energy production and conversion
  • CD630_21990 - Type: Gene
    Product:Putative ferredoxin/flavodoxin oxidoreductase,alpha subunit | Pathway: | COG: Energy production and conversion
  • CD630_22000 - hisC Type: Gene
    Product:Histidinol-phosphate aminotransferase | Pathway: Amino-acid biosynthesis | COG: Amino acid transport and metabolism
  • CD630_06190 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_21440 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
  • CD630_23740 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_22660 - Type: Gene
    Product:Putative oxidoreductase, FAD dependent | Pathway: | COG: Energy production and conversion
  • CD630_35420 - spmA Type: Gene
    Product:Spore maturation protein A | Pathway: | COG: Function unknown
  • CD630_21970 - Type: Gene
    Product:Putative ferredoxin/flavodoxin oxidoreductase,gamma subunit | Pathway: | COG: Energy production and conversion
  • CD630_23130 - Type: Gene
    Product:ABC-type transport system, molybdenum-likeATP-binding protein | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_32520 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_27530 - Type: Gene
    Product:Putative signaling protein | Pathway: | COG: Signal transduction mechanisms
  • CD630_21430 - Type: Gene
    Product:Transcriptional regulator, HTH-type | Pathway: | COG: Transcription
  • CD630_21980 - Type: Gene
    Product:Putative ferredoxin/flavodoxin oxidoreductase,beta subunit | Pathway: | COG: Energy production and conversion
  • CD630_23110 - Type: Gene
    Product:ABC-type transport system, molybdenum-likeextracellular solute-binding protein | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_06200 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_23750 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_23120 - Type: Gene
    Product:ABC-type transport system, molybdenum-likepermease | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_23140 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_35410 - spmB Type: Gene
    Product:Spore maturation protein B | Pathway: | COG: Function unknown
  • CD630_22650 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
  • CD630_21960 - Type: Gene
    Product:Putative succinyl-CoA synthetase-like ATP-bindingprotein | Pathway: | COG: Energy production and conversion
  • CD630_32510 - Type: Gene
    Product:Putative dehydrogenase | Pathway: | COG: Function unknown
0.000000000047 0.03 0.48 Inferelator: 2
Hypergeometric: 2

TF Influences from Inferelator

  1. CD630_25990 - Type: Gene
    Product:Putative transcriptional regulator | Pathway: | COG: Transcription
  2. CD630_26430 - sigE Type: Gene
    Product:RNA polymerase sigma-E factor | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

  1. CD630_12140 - spo0A Type: Gene
    Product:Stage 0 sporulation protein A | Pathway: | COG: Signal transduction mechanisms
  2. CD630_26430 - sigE Type: Gene
    Product:RNA polymerase sigma-E factor | Pathway: | COG: Transcription
Module_134 19
  • CD630_31320 - Type: Gene
    Product:PTS system, fructose-like IIA component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_03350 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_36300 - Type: Gene
    Product:PTS system, fructose/mannitol-family IIBcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_03370 - Type: Gene
    Product:ABC-type transport system, permease | Pathway: | COG: Defense mechanisms
  • CD630_36260 - Type: Gene
    Product:Putative 4-hydroxy-2-oxoglutarate aldolase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25520 - Type: Gene
    Product:Putative phosphosugar isomerase | Pathway: | COG: Function unknown
  • CD630_17350 - Type: Gene
    Product:Putative hydrolase | Pathway: | COG: Function unknown
  • CD630_36310 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_31310 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription
  • CD630_17370 - Type: Gene
    Product:Putative divalent ion symporter | Pathway: | COG: Amino acid transport and metabolism, Carbohydrate transport and metabolism
  • CD630_25530 - Type: Gene
    Product:PTS system, fructose/mannitol-family IICcomponent (Disrupted IStron) | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_17360 - Type: Gene
    Product:Transcriptional regulator, HTH-type | Pathway: | COG: Transcription
  • CD630_03380 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_25510 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_03390 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  • CD630_31330 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_17380 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
  • CD630_03360 - Type: Gene
    Product:ABC-type transport system, ATP-binding protein | Pathway: | COG: Defense mechanisms
  • CD630_17390 - Type: Gene
    Product:Two-component response regulator, sigma-54dependent regulator | Pathway: | COG: Signal transduction mechanisms
0.000017 NA 0.49 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_03390 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  2. CD630_30770 - Type: Gene
    Product:Transcriptional regulator, RpiR family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_87 7
  • CD630_35871 - Type: Gene
    Product:Fragment of putative transposase (N-terminalregion) | Pathway: | COG:
  • CD630_35940 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Energy production and conversion
  • CD630_00030 - Type: Gene
    Product:Putative RNA-binding mediating protein | Pathway: | COG: Function unknown
  • CD630_20990 - XdhD Type: Gene
    Product:Xanthine dehydrogenase subunit XdhD,molybdopterin-binding | Pathway: | COG: Energy production and conversion
  • CD630_35930 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_21010 - xdhB Type: Gene
    Product:Xanthine dehydrogenase subunit XdhB, FAD-binding | Pathway: | COG: Energy production and conversion
  • CD630_21000 - XdhC3 Type: Gene
    Product:Xanthine dehydrogenase iron-sulfur bindingsubunit XdhC3 | Pathway: | COG: Energy production and conversion
NA NA 0.49 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_06480 - Type: Gene
    Product:Transcriptional regulator, GntR family | Pathway: | COG: Transcription
  2. CD630_35830 - Type: Gene
    Product:Transcriptional regulator, MerR family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_294 26
  • CD630_10460 - pepT Type: Gene
    Product:Peptidase T | Pathway: | COG: Amino acid transport and metabolism
  • CD630_26450 - Type: Gene
    Product:ABC-type transport system, sugar-familyextracellular solute-binding protein | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_30330 - trxA Type: Gene
    Product:Thioredoxin | Pathway: | COG: Posttranslational modification, protein turnover, chaperones
  • CD630_30350 - Type: Gene
    Product:Putative diaminopimelate epimerase, PhzF family | Pathway: | COG: Function unknown
  • CD630_04530 - Type: Gene
    Product:Putative hydrolase | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_04510 - Type: Gene
    Product:Putative dioxygenase | Pathway: | COG: Function unknown
  • CD630_19700 - Type: Gene
    Product:Putative enzyme, cyclase family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_19690 - Type: Gene
    Product:Putative oligonucleotide binding regulator | Pathway: | COG: Function unknown
  • CD630_32810 - proC Type: Gene
    Product:Pyrroline-5-carboxylate reductase | Pathway: Amino-acid biosynthesis | COG: Amino acid transport and metabolism
  • CD630_07140 - Type: Gene
    Product:Putative protein involved in protein-proteininteractions | Pathway: | COG: Function unknown
  • CD630_16290 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_02020 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_06270 - Type: Gene
    Product:Putative transcriptional regulator, activatorMor | Pathway: | COG:
  • CD630_07121 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_17670 - gapB Type: Gene
    Product:Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_26460 - ftsZ Type: Gene
    Product:Cell division protein FtsZ | Pathway: | COG: Cell cycle control, cell division, chromosome partitioning
  • CD630_30340 - Type: Gene
    Product:Transcriptional regulator, TrmB family | Pathway: | COG: Transcription
  • CD630_21150 - Type: Gene
    Product:Putative copper-transporting P-type ATPase | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_04520 - Type: Gene
    Product:Putative hydrolase, NUDIX family | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_15780 - Type: Gene
    Product:Putative membrane-associated ribonuclease BN-like(Rbn) | Pathway: | COG: Function unknown
  • CD630_10450 - Type: Gene
    Product:Putative sporulation integral membrane protein | Pathway: | COG: Function unknown
  • CD630_19670 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_07150 - ptb Type: Gene
    Product:Phosphate butyryltransferase(Phosphotransbutyrylase) | Pathway: | COG: Energy production and conversion
  • CD630_06260 - Type: Gene
    Product:Putative replicative helicase DnaB-like | Pathway: | COG: Replication, recombination and repair
  • CD630_19680 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
  • CD630_07130 - Type: Gene
    Product:Putative radical SAM domain-containing protein | Pathway: | COG: Energy production and conversion
0.00000012 0.00043 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_18100 - Type: Gene
    Product:Transcriptional regulator, beta-lactamsrepressor | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_40 19
  • CD630_11041 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf18 | Pathway: | COG: Function unknown
  • CD630_11042 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf17 | Pathway: | COG: Function unknown
  • CD630_11050 - Type: Gene
    Product:Putative antirestriction protein Tn1549-like,CTn4-Orf16 | Pathway: | COG: Function unknown
  • CD630_11071 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf12 | Pathway: | COG: Function unknown
  • CD630_11070 - Type: Gene
    Product:Putative cell surface protein Tn1549-like,CTn4-Orf13 | Pathway: | COG: Function unknown
  • CD630_11061 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf14 | Pathway: | COG: Function unknown
  • CD630_33400 - Type: Gene
    Product:Putative antirestriction protein Tn916-like,CTn6-Orf17 | Pathway: | COG: Function unknown
  • CD630_33360 - Type: Gene
    Product:Putative cell wall hydrolase Tn916-like,CTn6-Orf13 | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_33280 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf4 | Pathway: | COG: Function unknown
  • CD630_11120 - Type: Gene
    Product:Putative membrane protein Tn1549-like, CTn4-Orf7 | Pathway: | COG: Function unknown
  • CD630_11080 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf11 | Pathway: | COG: Function unknown
  • CD630_33370 - Type: Gene
    Product:Putative membrane protein Tn916-like, CTn6-Orf14 | Pathway: | COG: Function unknown
  • CD630_11090 - Type: Gene
    Product:DNA-methyltransferase, cytosine-N4-specific;Tn1549-like, CTn4-Orf10 | Pathway: | COG: Replication, recombination and repair
  • CD630_33390 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf16 | Pathway: | COG: Function unknown
  • CD630_11060 - topB Type: Gene
    Product:DNA topoisomerase III; Tn1549-like, CTn4-Orf15 | Pathway: | COG: Replication, recombination and repair
  • CD630_33380 - Type: Gene
    Product:Putative ATPase Tn916-like, CTn6-Orf15 | Pathway: | COG: Function unknown
  • CD630_33350 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf12 | Pathway: | COG: Function unknown
  • CD630_11110 - Type: Gene
    Product:Putative conjugative transposon proteinTn1549-like, CTn4-Orf8 | Pathway: | COG: Function unknown
  • CD630_11100 - Type: Gene
    Product:Putative hydrolase Tn1549-like, CTn4-Orf9 | Pathway: | COG: Intracellular trafficking, secretion, and vesicular transport
0.00028 2.7 0.49 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_01710 - rex Type: Gene
    Product:Transcriptional regulator, Redox-sensingrepressor Rex | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_265 5
  • CD630_22600 - Type: Gene
    Product:Transporter, Major Facilitator Superfamily (MFS) | Pathway: | COG: Amino acid transport and metabolism
  • CD630_24220 - Type: Gene
    Product:Sodium:alanine symporter | Pathway: | COG: Amino acid transport and metabolism
  • CD630_12600 - brnQ-2 Type: Gene
    Product:Branched chain amino acid transport systemcarrier protein | Pathway: | COG: Amino acid transport and metabolism
  • CD630_24210 - Type: Gene
    Product:Putative amidohydrolase, M20D family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_31690 - Type: Gene
    Product:Putative malate transporter | Pathway: | COG: Function unknown
3.1 NA 0.49 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_10230 - Type: Gene
    Product:Putative transcriptional regulator, HTH | Pathway: | COG: Transcription
  2. CD630_15580 - sigV Type: Gene
    Product:Extra-Cytoplasmic Function sigma factors, ECFfamily | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_201 23
  • CD630_24870 - Type: Gene
    Product:PTS system, fructose-like IIB component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_30600 - Type: Gene
    Product:Phospho-alpha-glucosidase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25110 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_24650 - Type: Gene
    Product:Putative amino acid/polyamine transporter | Pathway: | COG: Amino acid transport and metabolism
  • CD630_24850 - Type: Gene
    Product:Putative Xaa-Pro aminopeptidase, M24 family | Pathway: | COG: Amino acid transport and metabolism
  • CD630_03900 - bglG Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_25090 - Type: Gene
    Product:Putative glycoside hydrolase, family 4 | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_05070 - Type: Gene
    Product:Putative conjugative transposon protein Tn5397,CTn3-Orf13 | Pathway: | COG: Function unknown
  • CD630_24890 - Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_30580 - Type: Gene
    Product:PTS system, alpha-glucoside-specific IIAcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_03880 - bglF Type: Gene
    Product:PTS system, beta-glucoside-specific IIABCcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25100 - Type: Gene
    Product:PTS system, glucose-like IIBC component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25120 - Type: Gene
    Product:PTS system, glucose-like IIA component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_24860 - Type: Gene
    Product:PTS system, fructose-like IIC component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_23280 - Type: Gene
    Product:Sigma-54 dpendent regulator, PTS fructose family | Pathway: | COG: Signal transduction mechanisms
  • CD630_24840 - Type: Gene
    Product:Putative pyridoxal phosphate-dependenttransferase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_25080 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription
  • CD630_05060 - Type: Gene
    Product:Reverse transcriptase/maturase/endonuclease,Group II intron | Pathway: | COG: Replication, recombination and repair
  • CD630_24880 - Type: Gene
    Product:PTS system, fructose-like IIA component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_30590 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG:
  • CD630_03890 - bglA Type: Gene
    Product:6-phospho-beta-glucosidase | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_25070 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_30570 - Type: Gene
    Product:Transporter, Major Facilitator Superfamily (MFS) | Pathway: | COG: Carbohydrate transport and metabolism
0 NA 0.49 Inferelator: 1
Hypergeometric: 1

TF Influences from Inferelator

  1. CD630_25080 - Type: Gene
    Product:Transcriptional regulator, AraC family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

  1. CD630_12750 - codY Type: Gene
    Product:Transcriptional regulator, GTP-sensingpleiotropic repressor | Pathway: | COG: Transcription
Module_26 6
  • CD630_07570 - Type: Gene
    Product:Phosphodiesterases protein | Pathway: | COG: Signal transduction mechanisms
  • CD630_18311 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_20160 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_18430 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_10150 - Type: Gene
    Product:Two-component sensor histidine kinase | Pathway: | COG: Signal transduction mechanisms
NA NA 0.49 Inferelator: 0
Hypergeometric: 0

TF Influences from Inferelator

No TF influences from Inferelator

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test