Module 255 Residual: 0.52

Title Bicluster Model Residual Score
bicluster_0255 v02 0.52 -12.73
Displaying 1 - 17 of 17
Rv0247c Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)

Details for Rv0247c - Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)

GO Terms: GO:0000104, GO:0005886

PATRIC Pathways: Oxidative phosphorylation, 2,4-Dichlorobenzoate degradation, Citrate cycle (TCA cycle), Butanoate metabolism, Reductive carboxylate cycle (CO2 fixation)

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0247c

Tuberculist Genomic Region

Rv0248c Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)

Details for Rv0248c - Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)

GO Terms: GO:0000104, GO:0005618, GO:0005886

PATRIC Pathways: Citrate cycle (TCA cycle), 2,4-Dichlorobenzoate degradation, Reductive carboxylate cycle (CO2 fixation), Butanoate metabolism, Oxidative phosphorylation

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0248c

Tuberculist Genomic Region

Rv0632c Enoyl-CoA hydratase

Details for Rv0632c - Enoyl-CoA hydratase

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.36 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0632c

Tuberculist Genomic Region

Rv2951c Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase

Details for Rv2951c - Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase

GO Terms: GO:0005829, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.95 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2951c

Tuberculist Genomic Region

Rv2952 Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase

Details for Rv2952 - Phthiotriol/phenolphthiotriol dimycocerosates methyltransferase

GO Terms: GO:0005886, GO:0008171, GO:0071770

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.64 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2952

Tuberculist Genomic Region

Rv2971 2,5-diketo-D-gluconic acid reductase (EC 1.1.1.-)

Details for Rv2971 - 2,5-diketo-D-gluconic acid reductase (EC 1.1.1.-)

GO Terms: GO:0016491, GO:0005886, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv2971

Tuberculist Genomic Region

Rv3464 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46)

Details for Rv3464 - dTDP-glucose 4,6-dehydratase (EC 4.2.1.46)

GO Terms: GO:0008460, GO:0005618, GO:0040007

PATRIC Pathways: Biosynthesis of vancomycin group antibiotics, Streptomycin biosynthesis, Polyketide sugar unit biosynthesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.12 | In vivo Essential: NA

Go to Gene Page: Rv3464

Tuberculist Genomic Region

Rv3465 dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13)

Details for Rv3465 - dTDP-4-dehydrorhamnose 3,5-epimerase (EC 5.1.3.13)

GO Terms: GO:0008830, GO:0008830, GO:0019305, GO:0040007, GO:0042803

PATRIC Pathways: Polyketide sugar unit biosynthesis, Streptomycin biosynthesis

Essentiality: Griffin Essential: 0.02 | In vitro Essential: 0.09 | In vivo Essential: NA

Go to Gene Page: Rv3465

Tuberculist Genomic Region

Rv3846 Superoxide dismutase [Mn/Fe] (EC 1.15.1.1)

Details for Rv3846 - Superoxide dismutase [Mn/Fe] (EC 1.15.1.1)

GO Terms: GO:0004784, GO:0005506, GO:0005576, GO:0005829, GO:0005886, GO:0006979, GO:0009405, GO:0042803, GO:0051289

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv3846

Tuberculist Genomic Region

Rv0164

Details for Rv0164 -

GO Terms: GO:0005576

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.04 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv0164

Tuberculist Genomic Region

Rv1099c Fructose-1,6-bisphosphatase, GlpX type (EC 3.1.3.11)

Details for Rv1099c - Fructose-1,6-bisphosphatase, GlpX type (EC 3.1.3.11)

GO Terms: GO:0042132, GO:0005829, GO:0006094, GO:0042132

PATRIC Pathways: Glycolysis / Gluconeogenesis, Methane metabolism, Carbon fixation in photosynthetic organisms, Fructose and mannose metabolism, Pentose phosphate pathway

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: 0.05

Go to Gene Page: Rv1099c

Tuberculist Genomic Region

Rv1436 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)

Details for Rv1436 - NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12)

GO Terms: GO:0004365, GO:0005576, GO:0005829, GO:0005886, GO:0040007

PATRIC Pathways: Glycolysis / Gluconeogenesis

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.19 | In vivo Essential: NA

Go to Gene Page: Rv1436

Tuberculist Genomic Region

Rv1437 Phosphoglycerate kinase (EC 2.7.2.3)

Details for Rv1437 - Phosphoglycerate kinase (EC 2.7.2.3)

GO Terms: GO:0004618, GO:0005576, GO:0005886, GO:0040007

PATRIC Pathways: Glycolysis / Gluconeogenesis, Carbon fixation in photosynthetic organisms

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv1437

Tuberculist Genomic Region

Rv1438 Triosephosphate isomerase (EC 5.3.1.1)

Details for Rv1438 - Triosephosphate isomerase (EC 5.3.1.1)

GO Terms: GO:0004807, GO:0004807, GO:0005576, GO:0005829, GO:0005886, GO:0040007, GO:0042803

PATRIC Pathways: Glycolysis / Gluconeogenesis, Carbon fixation in photosynthetic organisms, Inositol phosphate metabolism, Fructose and mannose metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.05 | In vivo Essential: NA

Go to Gene Page: Rv1438

Tuberculist Genomic Region

Rv2238c Alkyl hydroperoxide reductase subunit C-like protein

Details for Rv2238c - Alkyl hydroperoxide reductase subunit C-like protein

GO Terms: GO:0004601, GO:0042803, GO:0051260

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.53 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2238c

Tuberculist Genomic Region

Rv2239c

Details for Rv2239c -

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.86 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2239c

Tuberculist Genomic Region

Rv2970c lipase-esterase (lipN)

Details for Rv2970c - lipase-esterase (lipN)

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.88 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2970c

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 0.000011 e-value: 3.8
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 26 of 26
GO:0000104 |

succinate dehydrogenase activity

GO:0005886 |

plasma membrane

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0008171 |

O-methyltransferase activity

GO:0071770 |

DIM/DIP cell wall layer assembly

GO:0016491 |

oxidoreductase activity

GO:0040007 |

growth

GO:0008460 |

dTDP-glucose 4,6-dehydratase activity

GO:0008830 |

dTDP-4-dehydrorhamnose 3,5-epimerase activity

GO:0019305 |

dTDP-rhamnose biosynthetic process

GO:0042803 |

protein homodimerization activity

GO:0004784 |

superoxide dismutase activity

GO:0005506 |

iron ion binding

GO:0005576 |

extracellular region

GO:0006979 |

response to oxidative stress

GO:0009405 |

pathogenesis

GO:0051289 |

protein homotetramerization

GO:0042132 |

fructose 1,6-bisphosphate 1-phosphatase activity

GO:0006094 |

gluconeogenesis

GO:0004365 |

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity

GO:0004618 |

phosphoglycerate kinase activity

GO:0004807 |

triose-phosphate isomerase activity

GO:0004601 |

peroxidase activity

GO:0051260 |

protein homooligomerization