Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 81 - 90 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Title	Gene Count	Motif 1 e-value	Motif 2 e-value	Residual	TF Influences
Module_86	24 CD630_14940 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_27830 - Type: Gene Product:Putative glycosyl transferase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_21660 - msrAB Type: Gene Product:Peptide methionine sulfoxide reductase MsrA/MsrB \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_08180 - Type: Gene Product:6-phospho-beta-glucosidase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_14190 - Type: Gene Product:Putative diguanylate kinase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_28920 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_28900 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Function unknown CD630_14210 - Type: Gene Product:Putative diguanylate kinase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_09770 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Function unknown CD630_05440 - Type: Gene Product:Putative ornithine cyclodeaminase \| Pathway: \| COG: Amino acid transport and metabolism CD630_14950 - proC Type: Gene Product:Pyrroline-5-carboxylate reductase \| Pathway: Amino-acid biosynthesis \| COG: Amino acid transport and metabolism CD630_27780 - Type: Gene Product:Putative glycosyl transferase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_18080 - Type: Gene Product:Pyridoxal-dependent decarboxylase, group IVdecarboxylase family \| Pathway: \| COG: Amino acid transport and metabolism CD630_21670 - Type: Gene Product:Acyl transferase/acylhydrolase/lysophospholipase \| Pathway: \| COG: Function unknown CD630_27820 - cwp7 Type: Gene Product:Cell wall binding protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_08190 - Type: Gene Product:Transcription antiterminator, PTS operonregulator \| Pathway: \| COG: Transcription CD630_28910 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_14200 - dccA Type: Gene Product:Diguanylate cyclase protein \| Pathway: \| COG: Signal transduction mechanisms CD630_26680 - Type: Gene Product:Transcription antiterminator, licT family \| Pathway: \| COG: Transcription CD630_09750 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_09760 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_18070 - Type: Gene Product:Putative NADPH-dependent FMN reductase \| Pathway: \| COG: Function unknown CD630_16440 - Type: Gene Product:Transcriptional regulator, RmlC-type \| Pathway: \| COG: Transcription CD630_32040 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport	0.00000033	0	0.43	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_35440 - Type: Gene Product:Transcriptional regulator, AsnC/Lrp family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_6	27 CD630_07690 - Type: Gene Product:Putative oxidoreductase subunit \| Pathway: \| COG: Energy production and conversion CD630_18650 - Type: Gene Product:Putative DNA recombination protein Tn1549-like,CTn5-Orf24 \| Pathway: \| COG: Function unknown CD630_09820 - ubiA Type: Gene Product:Putative UbiA prenyltransferase \| Pathway: \| COG: Coenzyme transport and metabolism CD630_18670 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf26 \| Pathway: \| COG: Function unknown CD630_09840 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_13440 - Type: Gene Product:Putative cell wall biosynthesis protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_13460 - Type: Gene Product:Conserved hypothetical protein, DUF1700 \| Pathway: \| COG: Function unknown CD630_34880 - gtaB Type: Gene Product:UTP--glucose-1-phosphate uridylyltransferase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_13500 - cprB Type: Gene Product:ABC-type transport system, cationic antimicrobialpeptide resistance permease \| Pathway: \| COG: Function unknown CD630_13520 - cprK Type: Gene Product:Two-component sensor histidine kinase, cationicantimicrobial peptide resistance \| Pathway: \| COG: Signal transduction mechanisms CD630_27110 - Type: Gene Product:Transcriptional regulator, LysR family \| Pathway: \| COG: Transcription CD630_18680 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf27 \| Pathway: \| COG: Function unknown CD630_13480 - Type: Gene Product:Putative lipoprotein \| Pathway: \| COG: CD630_09810 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_18500 - Type: Gene Product:Transcriptional regulator, AraC family;Tn1549-like, CTn5-Orf6 \| Pathway: \| COG: Transcription CD630_15960 - map2 Type: Gene Product:Methionine aminopeptidase Map2 (MAP) (PeptidaseM) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_09830 - Type: Gene Product:Putative hydrolase, HAD superfamily, subfamilyIB \| Pathway: \| COG: Amino acid transport and metabolism CD630_13490 - cprA Type: Gene Product:ABC-type transport system, cationic antimicrobialpeptide resistance ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_13450 - Type: Gene Product:Transcriptional regulator, PadR family \| Pathway: \| COG: Transcription CD630_04880 - Type: Gene Product:Putative small multidrug resistance SugE-likeprotein \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_18660 - Type: Gene Product:Putative conjugative transposon proteintn1549-like, CTn5-Orf25 \| Pathway: \| COG: Function unknown CD630_18640 - Type: Gene Product:Transcriptional regulator, HTH-type Tn1549-like,CTn5-Orf23 \| Pathway: \| COG: Transcription CD630_13470 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_13510 - cprC Type: Gene Product:ABC-type transport system, cationic antimicrobialpeptide resistance permease \| Pathway: \| COG: Function unknown CD630_34890 - Type: Gene Product:Putative oligoendopeptidase F, peptidase M3Bfamily \| Pathway: \| COG: Amino acid transport and metabolism CD630_14380 - Type: Gene Product:Putative TPR repeat-containing protein \| Pathway: \| COG: Function unknown CD630_23920 - Type: Gene Product:Putative tRNA-binding protein \| Pathway: \| COG: Function unknown	0	0.00039	0.43	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_26400 - nrdR Type: Gene Product:Transcriptional regulator, repressor NrdR family \| Pathway: \| COG: Transcription CD630_26430 - sigE Type: Gene Product:RNA polymerase sigma-E factor \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_375	15 CD630_24040 - Type: Gene Product:DNA topoisomerase type IA \| Pathway: \| COG: Replication, recombination and repair CD630_15400 - Type: Gene Product:ABC-type transport system, permease protein \| Pathway: \| COG: Defense mechanisms CD630_15030 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_15410 - Type: Gene Product:Putative drug/sodium antiporter, MATE family \| Pathway: \| COG: Defense mechanisms CD630_31050 - Type: Gene Product:Putative iron-containing alcohol dehydrogenase \| Pathway: \| COG: Energy production and conversion CD630_31040 - Type: Gene Product:Putative hydrolase, HAD superfamily, IIBsubfamily; putative sugar phosphatase \| Pathway: \| COG: Function unknown CD630_03330 - ppaC Type: Gene Product:Putative inorganic pyrophosphatase \| Pathway: \| COG: Energy production and conversion CD630_15330 - Type: Gene Product:ABC-type transport system, permease \| Pathway: \| COG: Defense mechanisms CD630_28230 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_33610 - Type: Gene Product:Putative drug/sodium antiporter, MATE family \| Pathway: \| COG: Defense mechanisms CD630_31030 - Type: Gene Product:PTS system, glucose-like IIA component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_15040 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_15320 - Type: Gene Product:ABC-type transport system, ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_14650 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_15050 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG:	0.001	`NA`	0.43	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_10640 - ccpA Type: Gene Product:Transcriptional regulator, LacI family \| Pathway: \| COG: Transcription CD630_32800 - Type: Gene Product:Sigma-54 dpendent regulator, PTS fructose family \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_323	22 CD630_19170 - eutE Type: Gene Product:Ethanolamine acetaldehyde oxydoreductase \| Pathway: \| COG: Energy production and conversion CD630_30920 - Type: Gene Product:Putative amino acid permease \| Pathway: \| COG: Amino acid transport and metabolism CD630_19480 - Type: Gene Product:ABC-type transport system, permease \| Pathway: \| COG: Defense mechanisms CD630_31020 - Type: Gene Product:Putative peptidase, M20 family, peptidase Vrelated \| Pathway: \| COG: Amino acid transport and metabolism CD630_32110 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_06500 - Type: Gene Product:Putative peptidase, S9 family \| Pathway: \| COG: Amino acid transport and metabolism CD630_19470 - Type: Gene Product:ABC-type transport system, ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_19230 - Type: Gene Product:Ethanolamine carboxysome structural protein, BMCfamily \| Pathway: \| COG: Amino acid transport and metabolism CD630_19250 - eutQ Type: Gene Product:Ethanolamine utilization protein, Cupin barrelsfamily \| Pathway: \| COG: Amino acid transport and metabolism CD630_20010 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_30930 - Type: Gene Product:Putative gamma-glutamyl-gamma-aminobutyratehydrolase \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_06490 - Type: Gene Product:Putative peptidase, S9 family \| Pathway: \| COG: Amino acid transport and metabolism CD630_32100 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_31150 - bglA Type: Gene Product:6-phospho-beta-glucosidase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_32090 - Type: Gene Product:Transcriptional regulator, PadR family \| Pathway: \| COG: Transcription CD630_31010 - Type: Gene Product:PTS system, glucose-like IIBC component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_06510 - Type: Gene Product:Putative permease \| Pathway: \| COG: Function unknown CD630_19190 - eutT Type: Gene Product:Ethanolamine corrinoid cobalaminadenosyltransferase \| Pathway: \| COG: Amino acid transport and metabolism CD630_32201 - Type: Gene Product:Small acid-soluble spore protein \| Pathway: \| COG: Function unknown CD630_32200 - Type: Gene Product:Putative methyltransferase \| Pathway: \| COG: Secondary metabolites biosynthesis, transport and catabolism CD630_19200 - eutD Type: Gene Product:Putative phosphotransacetylase \| Pathway: Polyol metabolism \| COG: Secondary metabolites biosynthesis, transport and catabolism CD630_19240 - eutH Type: Gene Product:Ethanolamine transport protein \| Pathway: \| COG: Amino acid transport and metabolism	0.01	`NA`	0.43	Inferelator: 0 Hypergeometric: 1 TF Influences from Inferelator `No TF influences from Inferelator` TF Influences from Hypergeometric Test CD630_32450 - prdR Type: Gene Product:Transcriptional regulator, sigma-54-dependent \| Pathway: \| COG: Transcription
Module_228	20 CD630_11480 - Type: Gene Product:Putative penicillin-binding protein with aN-terminal TonB-box \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_21360 - uppS Type: Gene Product:Undecaprenyl pyrophosphate synthetase \| Pathway: \| COG: Lipid transport and metabolism CD630_21361 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_23340 - mtlA Type: Gene Product:PTS system, mannitol-specific, IICB component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_11510 - minE Type: Gene Product:Cell division topological specificity factor \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_21380 - pyrH Type: Gene Product:Uridylate kinase (UK) (Uridine monophosphatekinase) (UMP kinase) (UMPK) \| Pathway: Pyrimidine metabolism \| COG: Nucleotide transport and metabolism CD630_21350 - cdsA Type: Gene Product:Phosphatidate cytidylyltransferase CdsA \| Pathway: Phospholipid metabolism \| COG: Lipid transport and metabolism CD630_11530 - mgsA Type: Gene Product:Methylglyoxal synthase (MGS) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_11460 - mreC Type: Gene Product:Rod shape-determining protein MreC \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_11520 - mrdB Type: Gene Product:Rod shape-determining protein MrdB \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_23320 - mtlF Type: Gene Product:PTS system, mannitol-specific, EIIA component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_23330 - mtlR Type: Gene Product:Transcription antiterminator, PTS operonregulator \| Pathway: \| COG: Transcription CD630_21400 - rpsB Type: Gene Product:30S ribosomal protein S2 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_23310 - mtlD Type: Gene Product:Mannitol-1-phosphate 5-dehydrogenase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_11470 - Type: Gene Product:Putative permease \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_11450 - mreB2 Type: Gene Product:Rod shape-determining protein MreB \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_11440 - radC Type: Gene Product:DNA repair protein RadC homolog \| Pathway: \| COG: Replication, recombination and repair CD630_11490 - minC Type: Gene Product:Cell division regulator (septum placement) \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_21390 - tsf Type: Gene Product:Elongation factor Ts (EF-Ts) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_11430 - Type: Gene Product:Putative Maf-like protein \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning	`NA`	`NA`	0.43	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_16860 - Type: Gene Product:Transcriptional regulator, repressor-like \| Pathway: \| COG: Transcription CD630_17820 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_230	19 CD630_28040 - queA Type: Gene Product:S-adenosylmethionine:tRNAribosyltransferase-isomerase (Queuosine biosynthesisprotein QueA) \| Pathway: tRNA modification \| COG: Translation, ribosomal structure and biogenesis CD630_11650 - Type: Gene Product:Putative ribosome-associated protein \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_28020 - tgt Type: Gene Product:Queuine tRNA-ribosyltransferase (tRNA-guaninetransglycosylase) (Guanine insertion enzyme) \| Pathway: tRNA modification \| COG: Translation, ribosomal structure and biogenesis CD630_11640 - obgE Type: Gene Product:Spo0B-associated GTP-binding protein \| Pathway: \| COG: Energy production and conversion CD630_15690 - Type: Gene Product:Transcriptional regulator, MarR family \| Pathway: \| COG: Transcription CD630_11600 - rng Type: Gene Product:Ribonuclease G (RNase G) (Cytoplasmic axialfilament protein) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_11620 - Type: Gene Product:Putative ribosome-associated protein \| Pathway: \| COG: Function unknown CD630_28030 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_11630 - rpmA Type: Gene Product:50S ribosomal protein L27 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_05290 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_11610 - rplU Type: Gene Product:50S ribosomal protein L21 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_05300 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_05280 - Type: Gene Product:Putative amidohydrolase \| Pathway: \| COG: Amino acid transport and metabolism CD630_11580 - Type: Gene Product:Putative radical SAM-superfamily protein \| Pathway: \| COG: Energy production and conversion CD630_19660 - Type: Gene Product:Putative acyl-CoA thioesterase \| Pathway: \| COG: Function unknown CD630_28010 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_28000 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_11590 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_15700 - Type: Gene Product:Putative lysophospholipase (Disrupted by IStron) \| Pathway: \| COG: Lipid transport and metabolism, Lipid transport and metabolism	0.03	`NA`	0.43	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_06480 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_216	20 CD630_21490 - Type: Gene Product:Putative vancomycin resistance protein, vanWfamily \| Pathway: \| COG: Defense mechanisms CD630_21480 - Type: Gene Product:Putative serine/threonine protein kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_23980 - Type: Gene Product:Putative 2-thiocytidine tRNA biosynthesis proteinTtcA \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_06760 - rsiT Type: Gene Product:Anti Sigma factors, ECF family \| Pathway: \| COG: Function unknown CD630_36790 - rnpA Type: Gene Product:Ribonuclease P protein component (RNaseP protein)(RNase P protein) (Protein C5) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00470 - ispD Type: Gene Product:2-C-methyl-D-erythritol 4-phosphatecytidylyltransferase \| Pathway: Isoprenoid biosynthesis \| COG: Lipid transport and metabolism CD630_22121 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_00480 - ispF Type: Gene Product:2-C-methyl-D-erythritol 2,4-cyclodiphosphatesynthase \| Pathway: Isoprenoid biosynthesis \| COG: Lipid transport and metabolism CD630_32550 - rgaR Type: Gene Product:Two-component response regulator VirR-like \| Pathway: \| COG: Signal transduction mechanisms CD630_23970 - Type: Gene Product:Putative exonuclease \| Pathway: \| COG: Replication, recombination and repair CD630_36760 - mnmE Type: Gene Product:tRNA modification GTPase MnmE \| Pathway: \| COG: Function unknown CD630_36800 - rpmH Type: Gene Product:50S ribosomal protein L34 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_36780 - oxaA1 Type: Gene Product:Sporulation membrane protein SpoIIIJ \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_36781 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_06770 - sigT Type: Gene Product:Extra-Cytoplasmic Function sigma factors, ECFfamily \| Pathway: \| COG: Transcription CD630_36770 - Type: Gene Product:Putative SpoIIIJ-associated RNA/ssDNA-bindingprotein Jag \| Pathway: \| COG: Function unknown CD630_19970 - Type: Gene Product:Putative proline iminopeptidase (PIP), S33family \| Pathway: \| COG: Function unknown CD630_19980 - Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription CD630_21320 - Type: Gene Product:Putative transcriptional regulator \| Pathway: \| COG: Transcription CD630_36750 - mnmG Type: Gene Product:tRNA uridine 5-carboxymethylaminomethylmodification enzyme MnmG (Glucose-inhibited divisionprotein A) \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning	0	`NA`	0.44	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_06480 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_21110 - Type: Gene Product:Transcriptional regulator, DeoR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_296	25 CD630_13900 - Type: Gene Product:Conserved hypothetical protein, DUF819 family \| Pathway: \| COG: Function unknown CD630_12930 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_02330 - fliW Type: Gene Product:Flagellar assembly factor FliW \| Pathway: \| COG: Signal transduction mechanisms CD630_02260 - Type: Gene Product:Putative lytic transglycosylase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_02370 - fliD Type: Gene Product:Flagellar hook-associated protein 2 FliD (orHAP2) \| Pathway: \| COG: Cell motility CD630_02310 - flgK Type: Gene Product:Flagellar hook-associated protein FlgK (or HAP1) \| Pathway: \| COG: Cell motility CD630_02350 - fliS1 Type: Gene Product:Flagellar protein FliS1 \| Pathway: \| COG: Cell motility CD630_06540 - Type: Gene Product:ABC-type transport system, permease protein \| Pathway: \| COG: Function unknown CD630_02270 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_13890 - Type: Gene Product:Putative chloromuconate cycloisomerase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_06520 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_25390 - rnz Type: Gene Product:Ribonuclease Z (RNase Z) (tRNase Z) (tRNA 3endonuclease) \| Pathway: \| COG: Function unknown CD630_02280 - fliN Type: Gene Product:Flagellar motor switch protein FliN \| Pathway: \| COG: Cell motility CD630_02380 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_12920 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_02320 - flgL Type: Gene Product:Flagellar hook-associated protein FlgL (or HAP3) \| Pathway: \| COG: Cell motility CD630_02300 - Type: Gene Product:Putative flagellar biosynthesis protein \| Pathway: \| COG: Function unknown CD630_02400 - Type: Gene Product:Glycosyltransferase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_02340 - csrA Type: Gene Product:Carbon storage regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_02360 - fliS2 Type: Gene Product:Flagellar protein FliS2 \| Pathway: \| COG: Cell motility CD630_06530 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_28850 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_25380 - Type: Gene Product:Putative lipoprotein \| Pathway: \| COG: Function unknown CD630_02290 - flgM Type: Gene Product:Anti-sigma factor repressor of sigma(D)-dependenttranscription \| Pathway: \| COG: CD630_02390 - fliC Type: Gene Product:Flagellin C \| Pathway: \| COG: Cell motility	0.04	3.9	0.44	Inferelator: 2 Hypergeometric: 1 TF Influences from Inferelator CD630_12990 - Type: Gene Product:Transcriptional regulator, MarR family \| Pathway: \| COG: Transcription CD630_32800 - Type: Gene Product:Sigma-54 dpendent regulator, PTS fructose family \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test CD630_02660 - sigD Type: Gene Product:RNA polymerase sigma-28 factor for flagellaroperon \| Pathway: \| COG: Transcription
Module_351	3 CD630_12650 - Type: Gene Product:Transcriptional regulator, CarD family \| Pathway: \| COG: Transcription CD630_26330 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Energy production and conversion CD630_20660 - Type: Gene Product:Putative integrase \| Pathway: \| COG: Replication, recombination and repair	`NA`	`NA`	0.44	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_12650 - Type: Gene Product:Transcriptional regulator, CarD family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_131	3 CD630_22950 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_15100 - Type: Gene Product:Conserved hypothetical protein, DUF1121 family \| Pathway: \| COG: Function unknown CD630_26170 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown	`NA`	`NA`	0.44	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_15100 - Type: Gene Product:Conserved hypothetical protein, DUF1121 family \| Pathway: \| COG: Function unknown TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`