Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 71 - 80 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Title	Gene Count	Motif 1 e-value	Motif 2 e-value	Residual	TF Influences
Module_171	21 CD630_25740 - thiN Type: Gene Product:Thiamine pyrophosphokinase (TPK) (Thiaminediphospho kinase) \| Pathway: \| COG: Coenzyme transport and metabolism CD630_25830 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_25850 - def2 Type: Gene Product:Peptide deformylase 2 (PDF 2) (Polypeptidedeformylase 2 ) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_25840 - fmt Type: Gene Product:Methionyl-tRNA formyltransferase \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_25810 - rsmB Type: Gene Product:Ribosomal RNA small subunit methyltransferase B(rRNA (cytosine-C(5)-)-methyltransferase) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_16870 - Type: Gene Product:Putative lipoprotein \| Pathway: \| COG: CD630_25760 - Type: Gene Product:Putative GTPase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_25800 - Type: Gene Product:Putative radical SAM-family protein \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_25820 - Type: Gene Product:Putative metal-dependent peptidase \| Pathway: \| COG: Function unknown CD630_16880 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_25890 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_25750 - rpe Type: Gene Product:Ribulose-phosphate 3-epimerase(Pentose-5-phosphate 3-epimerase) (PPE) (R5P3E) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_16890 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_25880 - gmk Type: Gene Product:Guanylate kinase (GMP kinase) \| Pathway: \| COG: Nucleotide transport and metabolism CD630_16850 - Type: Gene Product:Putative binding protein \| Pathway: \| COG: Replication, recombination and repair CD630_25860 - priA Type: Gene Product:Primosomal protein N' (ATP-dependent helicasepriA) (Replication factor Y) \| Pathway: \| COG: Replication, recombination and repair CD630_25871 - rpoZ Type: Gene Product:DNA-directed RNA polymerase subunit omega (RNAPomega subunit) (Transcriptase subunit omega) (RNApolymerase omega subunit) \| Pathway: \| COG: Transcription CD630_19970 - Type: Gene Product:Putative proline iminopeptidase (PIP), S33family \| Pathway: \| COG: Function unknown CD630_19980 - Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription CD630_25870 - coaBC Type: Gene Product:Coenzyme A biosynthesis bifunctional proteinCoaBC; phosphopantothenoylcysteinesynthetase/decarboxylase \| Pathway: Cofactor biosynthesis \| COG: Coenzyme transport and metabolism CD630_16860 - Type: Gene Product:Transcriptional regulator, repressor-like \| Pathway: \| COG: Transcription	3.2	`NA`	0.42	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_17820 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_153	21 CD630_26850 - Type: Gene Product:Putative sporulation stage II, protein E \| Pathway: \| COG: Signal transduction mechanisms CD630_18910 - Type: Gene Product:Fragment of ABC-type transport system,substrate-binding protein (Part 2) \| Pathway: \| COG: Inorganic ion transport and metabolism, Inorganic ion transport and metabolism	`NA`	`NA`	0.42	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_11770 - fapR Type: Gene Product:Transcriptional regulator, DeoR family (Fattyacid and phospholipid biosynthesis regulator) \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_257	7 CD630_17410 - Type: Gene Product:Selenoprotein B,glycine/betaine/sarcosine/D-proline reductase family(sarcosine reductase) \| Pathway: \| COG: Function unknown CD630_08580 - Type: Gene Product:Fragment of transcriptional regulator,sigma-54-dependent (Part 1), PRD domain \| Pathway: \| COG: Signal transduction mechanisms, Signal transduction mechanisms CD630_31001 - Type: Gene Product:Fragment of artefact \| Pathway: \| COG: CD630_27000 - Type: Gene Product:Transcriptional regulator, sigma-54 dependent \| Pathway: \| COG: Transcription CD630_05990 - Type: Gene Product:Fragment of transcriptional regulator, AraCfamily (C-terminal region) \| Pathway: \| COG: Transcription CD630_05460 - Type: Gene Product:Putative membrane protein, DUF975 family \| Pathway: \| COG: Function unknown CD630_23950 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown	`NA`	`NA`	0.42	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_26400 - nrdR Type: Gene Product:Transcriptional regulator, repressor NrdR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_179	26 CD630_01080 - nrdD Type: Gene Product:Anaerobic ribonucleoside triphosphate reductase \| Pathway: \| COG: Nucleotide transport and metabolism CD630_11650 - Type: Gene Product:Putative ribosome-associated protein \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_r0050 - 23s_rRNA Type: Gene Product: \| Pathway: \| COG: CD630_r0280 - 23s_rRNA Type: Gene Product: \| Pathway: \| COG: CD630_11630 - rpmA Type: Gene Product:50S ribosomal protein L27 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_11610 - rplU Type: Gene Product:50S ribosomal protein L21 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_06770 - sigT Type: Gene Product:Extra-Cytoplasmic Function sigma factors, ECFfamily \| Pathway: \| COG: Transcription CD630_11590 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_11640 - obgE Type: Gene Product:Spo0B-associated GTP-binding protein \| Pathway: \| COG: Energy production and conversion CD630_24400 - Type: Gene Product:Putative metal-dependent hydrolase \| Pathway: \| COG: Nucleotide transport and metabolism CD630_r0230 - 23s_rRNA Type: Gene Product: \| Pathway: \| COG: CD630_t0810 - tRNA-Leu Type: Gene Product: \| Pathway: \| COG: CD630_01090 - nrdG Type: Gene Product:Anaerobic ribonucleoside-triphosphatereductase-activating protein \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_31760 - glnF Type: Gene Product:RNA polymerase sigma-54 factor \| Pathway: \| COG: Transcription CD630_11600 - rng Type: Gene Product:Ribonuclease G (RNase G) (Cytoplasmic axialfilament protein) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_11620 - Type: Gene Product:Putative ribosome-associated protein \| Pathway: \| COG: Function unknown CD630_24390 - Type: Gene Product:Putative diacylglycerol kinase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_11580 - Type: Gene Product:Putative radical SAM-superfamily protein \| Pathway: \| COG: Energy production and conversion CD630_06760 - rsiT Type: Gene Product:Anti Sigma factors, ECF family \| Pathway: \| COG: Function unknown CD630_01070 - aspC Type: Gene Product:Aspartate aminotransferase \| Pathway: \| COG: Amino acid transport and metabolism CD630_24360 - Type: Gene Product:Putative divalent cation transporter, MgtEfamily \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_r0150 - 5s_rRNA Type: Gene Product: \| Pathway: \| COG:	0.000000026	0.00000027	0.42	Inferelator: 4 Hypergeometric: 0 TF Influences from Inferelator CD630_06480 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_16920 - Type: Gene Product:Transcriptional regulator, ArsR family \| Pathway: \| COG: Transcription CD630_23900 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription CD630_30540 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_228	20 CD630_11480 - Type: Gene Product:Putative penicillin-binding protein with aN-terminal TonB-box \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_21360 - uppS Type: Gene Product:Undecaprenyl pyrophosphate synthetase \| Pathway: \| COG: Lipid transport and metabolism CD630_21361 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_23340 - mtlA Type: Gene Product:PTS system, mannitol-specific, IICB component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_11510 - minE Type: Gene Product:Cell division topological specificity factor \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_21380 - pyrH Type: Gene Product:Uridylate kinase (UK) (Uridine monophosphatekinase) (UMP kinase) (UMPK) \| Pathway: Pyrimidine metabolism \| COG: Nucleotide transport and metabolism CD630_21350 - cdsA Type: Gene Product:Phosphatidate cytidylyltransferase CdsA \| Pathway: Phospholipid metabolism \| COG: Lipid transport and metabolism CD630_11530 - mgsA Type: Gene Product:Methylglyoxal synthase (MGS) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_11460 - mreC Type: Gene Product:Rod shape-determining protein MreC \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_11520 - mrdB Type: Gene Product:Rod shape-determining protein MrdB \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_23320 - mtlF Type: Gene Product:PTS system, mannitol-specific, EIIA component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_23330 - mtlR Type: Gene Product:Transcription antiterminator, PTS operonregulator \| Pathway: \| COG: Transcription CD630_21400 - rpsB Type: Gene Product:30S ribosomal protein S2 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_23310 - mtlD Type: Gene Product:Mannitol-1-phosphate 5-dehydrogenase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_11470 - Type: Gene Product:Putative permease \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_11450 - mreB2 Type: Gene Product:Rod shape-determining protein MreB \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_11440 - radC Type: Gene Product:DNA repair protein RadC homolog \| Pathway: \| COG: Replication, recombination and repair CD630_11490 - minC Type: Gene Product:Cell division regulator (septum placement) \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_21390 - tsf Type: Gene Product:Elongation factor Ts (EF-Ts) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_11430 - Type: Gene Product:Putative Maf-like protein \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning	`NA`	`NA`	0.43	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_16860 - Type: Gene Product:Transcriptional regulator, repressor-like \| Pathway: \| COG: Transcription CD630_17820 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_230	19 CD630_28040 - queA Type: Gene Product:S-adenosylmethionine:tRNAribosyltransferase-isomerase (Queuosine biosynthesisprotein QueA) \| Pathway: tRNA modification \| COG: Translation, ribosomal structure and biogenesis CD630_11650 - Type: Gene Product:Putative ribosome-associated protein \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_28020 - tgt Type: Gene Product:Queuine tRNA-ribosyltransferase (tRNA-guaninetransglycosylase) (Guanine insertion enzyme) \| Pathway: tRNA modification \| COG: Translation, ribosomal structure and biogenesis CD630_11640 - obgE Type: Gene Product:Spo0B-associated GTP-binding protein \| Pathway: \| COG: Energy production and conversion CD630_15690 - Type: Gene Product:Transcriptional regulator, MarR family \| Pathway: \| COG: Transcription CD630_11600 - rng Type: Gene Product:Ribonuclease G (RNase G) (Cytoplasmic axialfilament protein) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_11620 - Type: Gene Product:Putative ribosome-associated protein \| Pathway: \| COG: Function unknown CD630_28030 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_11630 - rpmA Type: Gene Product:50S ribosomal protein L27 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_05290 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_11610 - rplU Type: Gene Product:50S ribosomal protein L21 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_05300 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_05280 - Type: Gene Product:Putative amidohydrolase \| Pathway: \| COG: Amino acid transport and metabolism CD630_11580 - Type: Gene Product:Putative radical SAM-superfamily protein \| Pathway: \| COG: Energy production and conversion CD630_19660 - Type: Gene Product:Putative acyl-CoA thioesterase \| Pathway: \| COG: Function unknown CD630_28010 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_28000 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_11590 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_15700 - Type: Gene Product:Putative lysophospholipase (Disrupted by IStron) \| Pathway: \| COG: Lipid transport and metabolism, Lipid transport and metabolism	0.03	`NA`	0.43	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_06480 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_375	15 CD630_24040 - Type: Gene Product:DNA topoisomerase type IA \| Pathway: \| COG: Replication, recombination and repair CD630_15400 - Type: Gene Product:ABC-type transport system, permease protein \| Pathway: \| COG: Defense mechanisms CD630_15030 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_15410 - Type: Gene Product:Putative drug/sodium antiporter, MATE family \| Pathway: \| COG: Defense mechanisms CD630_31050 - Type: Gene Product:Putative iron-containing alcohol dehydrogenase \| Pathway: \| COG: Energy production and conversion CD630_31040 - Type: Gene Product:Putative hydrolase, HAD superfamily, IIBsubfamily; putative sugar phosphatase \| Pathway: \| COG: Function unknown CD630_03330 - ppaC Type: Gene Product:Putative inorganic pyrophosphatase \| Pathway: \| COG: Energy production and conversion CD630_15330 - Type: Gene Product:ABC-type transport system, permease \| Pathway: \| COG: Defense mechanisms CD630_28230 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_33610 - Type: Gene Product:Putative drug/sodium antiporter, MATE family \| Pathway: \| COG: Defense mechanisms CD630_31030 - Type: Gene Product:PTS system, glucose-like IIA component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_15040 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_15320 - Type: Gene Product:ABC-type transport system, ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_14650 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_15050 - Type: Gene Product:ABC-type transport system, multidrug-familypermease \| Pathway: \| COG:	0.001	`NA`	0.43	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_10640 - ccpA Type: Gene Product:Transcriptional regulator, LacI family \| Pathway: \| COG: Transcription CD630_32800 - Type: Gene Product:Sigma-54 dpendent regulator, PTS fructose family \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_35	9 CD630_31460 - Type: Gene Product:Fragment of putative sortase B (Part 1) \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_19904 - Type: Gene Product:Fragment of conserved hypothetical protein \| Pathway: \| COG: CD630_23910 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_09401 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_09780 - Type: Gene Product:Transcriptional regulator, beta-lactams repressorPhage-type \| Pathway: \| COG: CD630_19820 - Type: Gene Product:Fragment of putative phenazine biosynthesisprotein (Part 1) \| Pathway: \| COG: Function unknown, Function unknown CD630_12360 - Type: Gene Product:Fragment of putative phage protein (part 1) \| Pathway: \| COG: CD630_05780 - Type: Gene Product:Transporter, Major Facilitator Superfamily (MFS) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_22180 - int Type: Gene Product:Fragment of putative integrase (C-terminalregion) \| Pathway: \| COG: Replication, recombination and repair	`NA`	`NA`	0.43	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_05790 - Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_217	20 CD630_06860 - rpmI Type: Gene Product:50S ribosomal protein L35 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_13780 - Type: Gene Product:Transcriptional regulator, Phage-type \| Pathway: \| COG: Transcription CD630_14410 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_18270 - Type: Gene Product:Transcriptional regulator, MarR family \| Pathway: \| COG: Transcription CD630_11330 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_34970 - Type: Gene Product:Bifunctional protein [Includes: Tetrapyrrolemethylase; NTP pyrophosphohydrolase MazG] \| Pathway: \| COG: Function unknown CD630_11320 - Type: Gene Product:Putative heavy-metal transport/detoxificationprotein \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_35030 - pilD Type: Gene Product:Type IV prepilin leader peptidase \| Pathway: \| COG: Cell motility, Posttranslational modification, protein turnover, chaperones, Intracellular trafficking, secretion, and vesicular transport CD630_35040 - pilD Type: Gene Product:Type IV prepilin peptidase, A24A family \| Pathway: \| COG: Cell motility, Posttranslational modification, protein turnover, chaperones, Intracellular trafficking, secretion, and vesicular transport CD630_35130 - pilA Type: Gene Product:Type IV pilus secretion protein \| Pathway: \| COG: Function unknown CD630_21920 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_21160 - bipA Type: Gene Product:GTP-binding protein BipA \| Pathway: \| COG: Signal transduction mechanisms CD630_11310 - Type: Gene Product:Putative solute-binding lipoprotein \| Pathway: \| COG: Amino acid transport and metabolism CD630_18280 - ftsH1 Type: Gene Product:Cell division protease FtsH1 \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_06870 - rplT Type: Gene Product:50S ribosomal protein L20 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_06850 - infC Type: Gene Product:Translation initiation factor IF-3 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_27180 - Type: Gene Product:Putative peptidase C60B, sortase B \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_34920 - Type: Gene Product:Septum formation initiation protein \| Pathway: \| COG: CD630_34940 - Type: Gene Product:Putative spore protein \| Pathway: \| COG: Function unknown CD630_32190 - hslO Type: Gene Product:33 kDa chaperonin (Heat shock protein 33 homolog)(HSP33) \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones	0.00019	`NA`	0.43	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_06700 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription CD630_26400 - nrdR Type: Gene Product:Transcriptional regulator, repressor NrdR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_86	24 CD630_14940 - Type: Gene Product:Transcriptional regulator, HTH-type \| Pathway: \| COG: Transcription CD630_27830 - Type: Gene Product:Putative glycosyl transferase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_21660 - msrAB Type: Gene Product:Peptide methionine sulfoxide reductase MsrA/MsrB \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_08180 - Type: Gene Product:6-phospho-beta-glucosidase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_14190 - Type: Gene Product:Putative diguanylate kinase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_28920 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_28900 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Function unknown CD630_14210 - Type: Gene Product:Putative diguanylate kinase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_09770 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Function unknown CD630_05440 - Type: Gene Product:Putative ornithine cyclodeaminase \| Pathway: \| COG: Amino acid transport and metabolism CD630_14950 - proC Type: Gene Product:Pyrroline-5-carboxylate reductase \| Pathway: Amino-acid biosynthesis \| COG: Amino acid transport and metabolism CD630_27780 - Type: Gene Product:Putative glycosyl transferase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_18080 - Type: Gene Product:Pyridoxal-dependent decarboxylase, group IVdecarboxylase family \| Pathway: \| COG: Amino acid transport and metabolism CD630_21670 - Type: Gene Product:Acyl transferase/acylhydrolase/lysophospholipase \| Pathway: \| COG: Function unknown CD630_27820 - cwp7 Type: Gene Product:Cell wall binding protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_08190 - Type: Gene Product:Transcription antiterminator, PTS operonregulator \| Pathway: \| COG: Transcription CD630_28910 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_14200 - dccA Type: Gene Product:Diguanylate cyclase protein \| Pathway: \| COG: Signal transduction mechanisms CD630_26680 - Type: Gene Product:Transcription antiterminator, licT family \| Pathway: \| COG: Transcription CD630_09750 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_09760 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_18070 - Type: Gene Product:Putative NADPH-dependent FMN reductase \| Pathway: \| COG: Function unknown CD630_16440 - Type: Gene Product:Transcriptional regulator, RmlC-type \| Pathway: \| COG: Transcription CD630_32040 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport	0.00000033	0	0.43	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_35440 - Type: Gene Product:Transcriptional regulator, AsnC/Lrp family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`