Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 271 - 280 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Filter by Module number e.g "401"
Filter by residual ( less than)
Filter by short name e.g "codY"
Title Gene Count Motif 1 e-value Motif 2 e-value Residual Expression TF Influences
Module_156 5
  • CD630_25010 - Type: Gene
    Product:Putative hydrolase, HAD superfamily, IIBsubfamily | Pathway: | COG: Function unknown
  • CD630_15980 - Type: Gene
    Product:Putative excinuclease ABC-like | Pathway: | COG: Replication, recombination and repair
  • CD630_23910 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG:
  • CD630_05320 - Type: Gene
    Product:Putative transcriptional regulator | Pathway: | COG: Transcription
  • CD630_23150 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
NA NA 0.54 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_23160 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_248 30
  • CD630_32120 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_34810 - Type: Gene
    Product:Protein-tyrosine phosphatase reductase | Pathway: | COG: Signal transduction mechanisms
  • CD630_34870 - rho Type: Gene
    Product:Transcription termination factor Rho | Pathway: | COG: Transcription
  • CD630_34850 - hemK Type: Gene
    Product:Modification methylase HemK | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_34830 - Type: Gene
    Product:Putative zinc/iron permease | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_10830 - Type: Gene
    Product:PTS system, lactose/cellobiose specific IIBcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_21780 - Type: Gene
    Product:Putative oxidoreductase, Fe-S subunit | Pathway: | COG: Energy production and conversion
  • CD630_09860 - rpsA Type: Gene
    Product:30S ribosomal protein S1 | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_10810 - moeA Type: Gene
    Product:Molybdenum cofactor biosynthesis protein | Pathway: Cofactor biosynthesis | COG: Coenzyme transport and metabolism
  • CD630_34860 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_14590 - Type: Gene
    Product:Putative FMN-binding protein | Pathway: | COG: Nucleotide transport and metabolism
  • CD630_34030 - Type: Gene
    Product:Putative formate/nitrite transporter | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_33090 - ligA Type: Gene
    Product:DNA ligase (Polydeoxyribonucleotide synthase[NAD+]) | Pathway: | COG: Replication, recombination and repair
  • CD630_27480 - Type: Gene
    Product:Putative acyltransferase | Pathway: | COG: Replication, recombination and repair
  • CD630_21850 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_22840 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_18000 - terD Type: Gene
    Product:Tellurium resistance protein | Pathway: | COG: Signal transduction mechanisms
  • CD630_32130 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_17671 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_34800 - rpiB2 Type: Gene
    Product:Ribose-5-phosphate isomerase 2 | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_10820 - mobB Type: Gene
    Product:Molybdopterin-guanine dinucleotide biosynthesisprotein B | Pathway: | COG: Coenzyme transport and metabolism
  • CD630_27490 - Type: Gene
    Product:Putative radical SAM-family protein | Pathway: | COG: Function unknown
  • CD630_34820 - Type: Gene
    Product:Putative RNA-binding protein | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_34861 - rpmE Type: Gene
    Product:50S ribosomal protein L31 | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_21790 - Type: Gene
    Product:Putative anaerobic dehydrogenase | Pathway: | COG: Energy production and conversion
  • CD630_34840 - prfA Type: Gene
    Product:Peptide chain release factor 1 (RF-1) | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_17990 - terD Type: Gene
    Product:Tellurium resistance protein | Pathway: | COG: Signal transduction mechanisms
  • CD630_34790 - upp Type: Gene
    Product:Uracil phosphoribosyltransferase (UMPpyrophosphorylase) (UPRTase) | Pathway: Pyrimidine metabolism | COG: Nucleotide transport and metabolism
  • CD630_17680 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
  • CD630_21860 - Type: Gene
    Product:Putative phage-like protein | Pathway: | COG:
0.06 NA 0.54 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_17820 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms
  2. CD630_27220 - Type: Gene
    Product:Two-component response regulator | Pathway: | COG: Signal transduction mechanisms

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_200 23
  • CD630_21700 - Type: Gene
    Product:Putative cNMP-binding regulatory protein | Pathway: | COG: Signal transduction mechanisms
  • CD630_26600 - Type: Gene
    Product:Putative peptidase, M16 family | Pathway: | COG: Posttranslational modification, protein turnover, chaperones
  • CD630_28660 - Type: Gene
    Product:Putative modulator of DNA gyrase, peptidase U62 | Pathway: | COG: Function unknown
  • CD630_16310 - sodA Type: Gene
    Product:Spore coat protein, superoxide dismutase | Pathway: | COG: Inorganic ion transport and metabolism
  • CD630_23470 - Type: Gene
    Product:Putative Xaa-Pro dipeptidase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_23000 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_28680 - Type: Gene
    Product:Putative oxidoreductase | Pathway: | COG: Energy production and conversion
  • CD630_17090 - mobA Type: Gene
    Product:Molybdopterin-guanine dinucleotide biosynthesisprotein A | Pathway: | COG: Coenzyme transport and metabolism
  • CD630_21690 - Type: Gene
    Product:Putative iron-sulfur binding protein | Pathway: | COG: Energy production and conversion
  • CD630_35780 - Type: Gene
    Product:Resolvase | Pathway: | COG: Replication, recombination and repair
  • CD630_26610 - Type: Gene
    Product:Putative peptidase, M16 family | Pathway: | COG: Posttranslational modification, protein turnover, chaperones
  • CD630_28670 - Type: Gene
    Product:Putative regulatory protease, U62 family | Pathway: | COG: Function unknown
  • CD630_17100 - Type: Gene
    Product:Putative NAD(P)-binding protein | Pathway: | COG: Function unknown
  • CD630_07820 - Type: Gene
    Product:Putative sporulation protein YunB | Pathway: | COG: Function unknown
  • CD630_16300 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
  • CD630_16320 - asnB Type: Gene
    Product:Asparagine synthetase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_19840 - Type: Gene
    Product:Putative hydrolase, NUDIX family | Pathway: | COG: Replication, recombination and repair
  • CD630_17080 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_23010 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_21680 - hcp Type: Gene
    Product:Hydroxylamine reductase | Pathway: | COG: Energy production and conversion
  • CD630_07390 - Type: Gene
    Product:Putative exported protein | Pathway: | COG:
  • CD630_35790 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_32040 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Intracellular trafficking, secretion, and vesicular transport
0.000000000021 0.0001 0.54 Inferelator: 4
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_12390 - Type: Gene
    Product:Transcriptional regulator, beta-lactams repressorPhage-type | Pathway: | COG: Transcription
  2. CD630_16860 - Type: Gene
    Product:Transcriptional regulator, repressor-like | Pathway: | COG: Transcription
  3. CD630_33530 - Type: Gene
    Product:Transcriptional regulator, GntR family | Pathway: | COG: Transcription
  4. CD630_34990 - spoVT Type: Gene
    Product:Stage V sporulation protein T | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_346 20
  • CD630_17050 - thiH Type: Gene
    Product:Thiamine biosynthesis protein ThiH | Pathway: | COG: Coenzyme transport and metabolism
  • CD630_04650 - Type: Gene
    Product:Transcriptional regulator, RpiR family | Pathway: | COG: Transcription
  • CD630_19000 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_04670 - Type: Gene
    Product:Putative hydrolase, HAD superfamily, subfamilyIIB | Pathway: | COG: Function unknown
  • CD630_17040 - thiG Type: Gene
    Product:Thiazole biosynthesis protein ThiG | Pathway: Cofactor biosynthesis | COG: Coenzyme transport and metabolism
  • CD630_31160 - bglF Type: Gene
    Product:PTS system, beta-glucoside-specific IIABCcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_17060 - thiE2 Type: Gene
    Product:Thiamine-phosphate pyrophosphorylase ThiE2 | Pathway: | COG: Coenzyme transport and metabolism
  • CD630_34600 - tkt Type: Gene
    Product:Transketolase, thiamine diphosphate bindingsubunit | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_34590 - tkt Type: Gene
    Product:Transketolase, pyridine binding subunit | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_31170 - bglG Type: Gene
    Product:Transcription antiterminator, PTS operonregulator | Pathway: | COG: Transcription
  • CD630_17020 - thiC Type: Gene
    Product:Thiamine biosynthesis protein ThiC | Pathway: Cofactor biosynthesis | COG: Coenzyme transport and metabolism
  • CD630_17021 - thiS Type: Gene
    Product:Thiamine biosynthesis protein ThiS | Pathway: | COG: Coenzyme transport and metabolism
  • CD630_17030 - thiF Type: Gene
    Product:Thiamine biosynthesis protein ThiF | Pathway: | COG: Coenzyme transport and metabolism
  • CD630_04680 - malL Type: Gene
    Product:oligo-1,6-glucosidase (Sucrase-isomaltase) | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_04690 - Type: Gene
    Product:PTS system, sucrose-specific IIABC component | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_17910 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_17880 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_17900 - Type: Gene
    Product:Putative exonuclease | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_04660 - Type: Gene
    Product:Transcriptional regulator, RpiR family | Pathway: | COG: Transcription
  • CD630_17890 - Type: Gene
    Product:Putative membrane protein, DUF421 family | Pathway: | COG: Function unknown
0.16 1.9 0.54 Inferelator: 0
Hypergeometric: 0

TF Influences from Inferelator

No TF influences from Inferelator

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_378 23
  • CD630_t0820 - tRNA-Leu Type: Gene
    Product: | Pathway: | COG:
  • CD630_t0740 - tRNA-Gly Type: Gene
    Product: | Pathway: | COG:
  • CD630_00200 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_17671 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_06421 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_32640 - Type: Gene
    Product:Fragment of conserved hypothetical protein(C-terminal region) | Pathway: | COG: Function unknown
  • CD630_26050 - Type: Gene
    Product:Fragment of ADP-ribosyltransferase CdtAB (Part3) | Pathway: | COG:
  • CD630_t0790 - tRNA-Ser Type: Gene
    Product: | Pathway: | COG:
  • CD630_21151 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_30200 - Type: Gene
    Product:Fragment of conserved hypothetical protein,DUF1848 family (Part 2) | Pathway: | COG: Function unknown
  • CD630_t0080 - tRNA-Val Type: Gene
    Product: | Pathway: | COG:
  • CD630_18440 - Type: Gene
    Product:Fragment of conserved hypothetical protein (Part1) | Pathway: | COG: Function unknown
  • CD630_06642 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_29730 - Type: Gene
    Product:Putative acetyltransferase | Pathway: | COG: Transcription
  • CD630_04390 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_31850 - Type: Gene
    Product:Fragment of putative RNA-binding protein (Part2) | Pathway: | COG: Function unknown, Function unknown
  • CD630_22250 - Type: Gene
    Product:Fragment of putative integrase (N-terminalregion) | Pathway: | COG: Replication, recombination and repair
  • CD630_t0020 - tRNA-Ser Type: Gene
    Product: | Pathway: | COG:
  • CD630_21820 - Type: Gene
    Product:Fragment of conserved hypothetical protein(C-terminal region) | Pathway: | COG: Function unknown
  • CD630_24790 - Type: Gene
    Product:Putative molybdenum cofactor biosynthesis | Pathway: | COG: Coenzyme transport and metabolism
  • CD630_36110 - Type: Gene
    Product:Fragment of putative drug/sodium antiporter, MATEfamily (Part 2) | Pathway: | COG: Defense mechanisms, Defense mechanisms
  • CD630_06360 - Type: Gene
    Product:Putative radical SAM superfamily protein, DUF85family | Pathway: | COG: Replication, recombination and repair
  • CD630_21251 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
0.0000025 0.03 0.54 Inferelator: 0
Hypergeometric: 0

TF Influences from Inferelator

No TF influences from Inferelator

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_111 23
  • CD630_03550 - int Type: Gene
    Product:Integrase Tn916-like, CTn1-Orf1 | Pathway: | COG: Replication, recombination and repair
  • CD630_33700 - Type: Gene
    Product:Putative recombinase Tn916-like, CTn7-Orf1 | Pathway: | COG: Replication, recombination and repair
  • CD630_15950 - cysE Type: Gene
    Product:Serine acetyltransferase (SAT) | Pathway: | COG: Amino acid transport and metabolism
  • CD630_05190 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_00190 - Type: Gene
    Product:Putative glycosyl transferase | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_26930 - Type: Gene
    Product:Sodium:dicarboxylate symporter family protein | Pathway: | COG: Energy production and conversion
  • CD630_34580 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG: Function unknown
  • CD630_21280 - ispG Type: Gene
    Product:4-hydroxy-3-methylbut-2-en-1-yl diphosphatesynthase | Pathway: Isoprenoid biosynthesis | COG: Lipid transport and metabolism
  • CD630_16960 - Type: Gene
    Product:Sodium:alanine symporter | Pathway: | COG: Amino acid transport and metabolism
  • CD630_35950 - Type: Gene
    Product:Aminopeptidase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_19410 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_21300 - dxr Type: Gene
    Product:1-deoxy-D-xylulose 5-phosphate reductoisomerase | Pathway: Isoprenoid biosynthesis | COG: Lipid transport and metabolism
  • CD630_09930 - Type: Gene
    Product:Putative thioesterase | Pathway: | COG: Function unknown
  • CD630_05081 - Type: Gene
    Product:Putative conjugative transposon protein Tn5397,CTn3-Orf6 | Pathway: | COG: Function unknown
  • CD630_15940 - cysK Type: Gene
    Product:O-acetyl-serine thiol-lyase A(O-acetyl-sulfhydrylase)(OAS-TL) | Pathway: | COG: Amino acid transport and metabolism
  • CD630_36140 - Type: Gene
    Product:Conserved hypothetical protein, DUF1130 family | Pathway: | COG: Function unknown
  • CD630_08610 - Type: Gene
    Product:PTS system, lactose/cellobiose-family IIBcomponent | Pathway: | COG: Carbohydrate transport and metabolism
  • CD630_02970 - bioB Type: Gene
    Product:Biotin synthase | Pathway: Cofactor biosynthesis | COG: Coenzyme transport and metabolism
  • CD630_21290 - Type: Gene
    Product:Putative membrane-associated peptidase, M50family | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_05650 - nth Type: Gene
    Product:Endonuclease III | Pathway: | COG: Replication, recombination and repair
  • CD630_08930 - Type: Gene
    Product:Putative iron-dependent hydrogenase | Pathway: | COG: Energy production and conversion
  • CD630_05610 - Type: Gene
    Product:Putative aldo/keto reductase ; putativeferredoxin | Pathway: | COG: Energy production and conversion
  • CD630_08070 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
0.000000000027 NA 0.54 Inferelator: 1
Hypergeometric: 1

TF Influences from Inferelator

  1. CD630_16930 - Type: Gene
    Product:Putative dinitrogenase iron-molybdenum cofactor | Pathway: | COG: Function unknown

TF Influences from Hypergeometric Test

  1. CD630_10640 - ccpA Type: Gene
    Product:Transcriptional regulator, LacI family | Pathway: | COG: Transcription
Module_396 4
  • CD630_06950 - Type: Gene
    Product:Putative exported metalloendopeptidase | Pathway: | COG: Amino acid transport and metabolism
  • CD630_09050 - Type: Gene
    Product:Putative phage protein | Pathway: | COG: Function unknown
  • CD630_15730 - Type: Gene
    Product:Transcriptional regulator, HTH-type | Pathway: | COG: Transcription
  • CD630_27060 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
NA NA 0.54 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_15730 - Type: Gene
    Product:Transcriptional regulator, HTH-type | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_333 18
  • CD630_26180 - ileS Type: Gene
    Product:Isoleucyl-tRNA synthetase | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_12860 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_32560 - valS Type: Gene
    Product:valyl-tRNA synthetase | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_35400 - metG Type: Gene
    Product:Methionyl-tRNA synthetase (Methionine--tRNAligase) (MetRS) | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_00500 - proS Type: Gene
    Product:Prolyl-tRNA synthetase | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_26950 - asnA Type: Gene
    Product:Aspartate--ammonia ligase (Asparagine synthetaseA) | Pathway: Amino-acid biosynthesis | COG: Amino acid transport and metabolism
  • CD630_26940 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG:
  • CD630_26100 - trpS Type: Gene
    Product:Tryptophanyl-tRNA synthetase (Tryptophan--tRNAligase) (TrpRS) | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_26110 - mtnN Type: Gene
    Product:MTA/SAH nucleosidase (5'-methylthioadenosinenucleosidase) (S-adenosylhomocysteine nucleosidase) | Pathway: Amino-acid biosynthesis | COG: Nucleotide transport and metabolism
  • CD630_35390 - Type: Gene
    Product:Putative deoxyribonuclease | Pathway: | COG: Replication, recombination and repair
  • CD630_00140 - serS1 Type: Gene
    Product:Seryl-tRNA synthetase 1 | Pathway: Aminoacyl-tRNA biosynthesis | COG: Translation, ribosomal structure and biogenesis
  • CD630_00490 - proS Type: Gene
    Product:Prolyl-tRNA synthetase | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_25210 - leuS Type: Gene
    Product:Leucyl-tRNA synthetase | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_07010 - Type: Gene
    Product:Putative cell-division protein | Pathway: | COG: Function unknown
  • CD630_12850 - Type: Gene
    Product:Putative Holliday junction resolvase | Pathway: | COG: Replication, recombination and repair
  • CD630_07000 - pheT Type: Gene
    Product:Phenylalanyl-tRNA synthetase subunit beta(Phenylalanine--tRNA ligase beta chain) (PheRS) | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_15210 - tyrS Type: Gene
    Product:Tyrosyl-tRNA synthetase (Tyrosine--tRNA ligase)(TyrRS) | Pathway: | COG: Translation, ribosomal structure and biogenesis
  • CD630_12820 - alaS Type: Gene
    Product:Alanyl-tRNA synthetase | Pathway: | COG: Translation, ribosomal structure and biogenesis
0 8.5e-16 0.54 Inferelator: 2
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_11770 - fapR Type: Gene
    Product:Transcriptional regulator, DeoR family (Fattyacid and phospholipid biosynthesis regulator) | Pathway: | COG: Transcription
  2. CD630_21110 - Type: Gene
    Product:Transcriptional regulator, DeoR family | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_254 4
  • CD630_18430 - Type: Gene
    Product:Conserved hypothetical protein | Pathway: | COG: Function unknown
  • CD630_02920 - Type: Gene
    Product:Transcriptional regulator, HTH-type | Pathway: | COG: Transcription
  • CD630_30070 - Type: Gene
    Product:Putative L,D-transpeptidases | Pathway: | COG: Cell wall/membrane/envelope biogenesis
  • CD630_29570 - ntpC Type: Gene
    Product:V-type sodium ATPase subunit C | Pathway: | COG: Energy production and conversion
NA NA 0.54 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_25950 - pyrR Type: Gene
    Product:Bifunctional protein PyrR [Includes: Pyrimidineoperon regulatory protein; Uracil phosphoribosyltransferase(UPRTase)] | Pathway: | COG: Nucleotide transport and metabolism

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test
Module_270 19
  • CD630_04990 - Type: Gene
    Product:Putative replication initiation factor Tn5397,CTn3-Orf20 | Pathway: | COG: Transcription
  • CD630_04991 - Type: Gene
    Product:Putative conjugative transposon protein Tn5397,CTn3-Orf19 | Pathway: | COG: Function unknown
  • CD630_05010 - Type: Gene
    Product:Putative conjugative transposon protein Tn5397,CTn3-Orf17 | Pathway: | COG: Function unknown
  • CD630_04980 - Type: Gene
    Product:Putative cell-division FtsK/SpoIIIE-familyprotein Tn5397, CTn3-Orf21 | Pathway: | COG: Cell cycle control, cell division, chromosome partitioning
  • CD630_05070 - Type: Gene
    Product:Putative conjugative transposon protein Tn5397,CTn3-Orf13 | Pathway: | COG: Function unknown
  • CD630_05030 - Type: Gene
    Product:Putative membrane protein Tn5397, CTn3-Orf15 | Pathway: | COG: Function unknown
  • CD630_04960 - Type: Gene
    Product:Putative conjugative transposon protein DUF961family Tn5397, CTn3-Orf23 | Pathway: | COG: Function unknown
  • CD630_33460 - Type: Gene
    Product:Putative conjugative transposon protein DUF961family Tn916-like, CTn6-Orf24 | Pathway: | COG: Function unknown
  • CD630_05020 - Type: Gene
    Product:Putative ATPase Tn5397, CTn3-Orf16 | Pathway: | COG: Function unknown
  • CD630_05000 - Type: Gene
    Product:Putative antirestriction protein Tn5397,CTn3-Orf18 | Pathway: | COG: Function unknown
  • CD630_04970 - Type: Gene
    Product:Putative conjugative transposon protein DUF961family Tn5397, CTn3-Orf22 | Pathway: | COG: Function unknown
  • CD630_33440 - Type: Gene
    Product:Putative cell-division FtsK/SpoIIIE-familyprotein Tn916-like, CTn6-Orf22 | Pathway: | COG: Cell cycle control, cell division, chromosome partitioning
  • CD630_09071 - Type: Gene
    Product:Transcriptional regulator, Phage-type | Pathway: | COG: Transcription
  • CD630_33450 - Type: Gene
    Product:Putative conjugative transposon proteinTn916-like, CTn6-Orf23 | Pathway: | COG: Function unknown
  • CD630_22222 - Type: Gene
    Product:Putative extrachromosomal origin protein | Pathway: | COG:
  • CD630_33470 - Type: Gene
    Product:Putative membrane protein | Pathway: | COG:
  • CD630_09080 - Type: Gene
    Product:Putative antirepressor protein | Pathway: | COG: Transcription
  • CD630_33480 - Type: Gene
    Product:Hypothetical protein | Pathway: | COG: Function unknown
  • CD630_09090 - Type: Gene
    Product:Putative phage protein | Pathway: | COG:
0.0000004 0.15 0.54 Inferelator: 1
Hypergeometric: 0

TF Influences from Inferelator

  1. CD630_36680 - rstA Type: Gene
    Product:Regulator of sporulation and toxins | Pathway: | COG: Transcription

TF Influences from Hypergeometric Test

No TF Influences from the hypergeometric test