Environment and Gene Regulatory Influence Network (EGRIN) model for C. difficile 630

The Environment and Gene Regulatory Influence Network (EGRIN) model of C. difficile 630 was inferred using cMonkey2 and a compendium of 136 transcriptomes (retrieved from the Gene Expression Omnibus repository) with 4,070 sequence features including 35 rRNAs and 90 tRNAs . The C. difficile EGRIN model groups genes in subsets (406 modules in total), that are co-regulated in specific environments, and also identifies the associated, putative cis-acting gene regulatory elements (GREs), which represent potential TF binding locations. Transcriptome compendium included conditions: response to iron limitation, response to oxygen, in vivo vs in vitro growth, short term infection (0, 30, 60, 120 mins), response to commensals and host diet, transition from exponential to stationary phase, fur KO, codY KO, sporulation TF (and sigma factors) KOs.

Explore Regulatory Modules

Displaying 91 - 100 of 406

Candidate transcriptional regulators for each module were determined with a linear regression based approach (Inferelator) and by evaluating the statistical significance of the overlap (Hypergeometric) between modules and putative TF and alternative sigma factor regulons (CcpA, CodY, Fur, PrdR, SigB, SigD, SigE, SigF, SigG, SigH, SigK, Spo0A) compiled from available literature.

* Given that translation start was used to define the 3' end of putative promoters, some cis-regulatory motifs are likely to be ribosome binding sites (i.e., Shine-Dalgarno sequence). RBS is typically a six nucleotide sequence 5'-GGAGGA-3'.

Title	Gene Count	Motif 1 e-value	Motif 2 e-value	Residual	TF Influences
Module_279	26 CD630_13960 - Type: Gene Product:Putative amino acid amidase \| Pathway: \| COG: Amino acid transport and metabolism CD630_30780 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_27010 - Type: Gene Product:Putative lipoprotein \| Pathway: \| COG: Function unknown CD630_30430 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_02160 - Type: Gene Product:Transposase IS200/IS605-like OrfB \| Pathway: \| COG: Replication, recombination and repair CD630_17300 - Type: Gene Product:Putative ATP-binding protein \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_24020 - Type: Gene Product:Putative cell wall hydrolase;phosphatase-associated protein \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_02120 - Type: Gene Product:Putative sulfatase \| Pathway: \| COG: Function unknown CD630_24040 - Type: Gene Product:DNA topoisomerase type IA \| Pathway: \| COG: Replication, recombination and repair CD630_31230 - Type: Gene Product:Putative nitroreductase \| Pathway: \| COG: Energy production and conversion CD630_13950 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: CD630_14970 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_05310 - Type: Gene Product:Transcriptional regulator, DeoR family \| Pathway: \| COG: Transcription CD630_11560 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_03050 - Type: Gene Product:Putative glutamate carboxypeptidase \| Pathway: \| COG: Amino acid transport and metabolism CD630_00100 - rsbW Type: Gene Product:Serine-protein kinase RsbW \| Pathway: \| COG: Signal transduction mechanisms CD630_02110 - licC Type: Gene Product:CTP:phosphocholine cytidylyltransferase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_00080 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_32590 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_08090 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_19310 - lexA Type: Gene Product:Transcriptional regulator, LexA repressor \| Pathway: \| COG: Transcription CD630_09231 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_19320 - Type: Gene Product:Putative phage integrase \| Pathway: \| COG: Replication, recombination and repair CD630_02150 - Type: Gene Product:Transposase IS200/IS605-like OrfA \| Pathway: \| COG: Replication, recombination and repair CD630_31220 - Type: Gene Product:Transcriptional regulator, ArsR family \| Pathway: \| COG: Transcription CD630_29260 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: Function unknown	0.000000029	0.35	0.44	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_18100 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_351	3 CD630_12650 - Type: Gene Product:Transcriptional regulator, CarD family \| Pathway: \| COG: Transcription CD630_26330 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Energy production and conversion CD630_20660 - Type: Gene Product:Putative integrase \| Pathway: \| COG: Replication, recombination and repair	`NA`	`NA`	0.44	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_12650 - Type: Gene Product:Transcriptional regulator, CarD family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_296	25 CD630_13900 - Type: Gene Product:Conserved hypothetical protein, DUF819 family \| Pathway: \| COG: Function unknown CD630_12930 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_02330 - fliW Type: Gene Product:Flagellar assembly factor FliW \| Pathway: \| COG: Signal transduction mechanisms CD630_02260 - Type: Gene Product:Putative lytic transglycosylase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_02370 - fliD Type: Gene Product:Flagellar hook-associated protein 2 FliD (orHAP2) \| Pathway: \| COG: Cell motility CD630_02310 - flgK Type: Gene Product:Flagellar hook-associated protein FlgK (or HAP1) \| Pathway: \| COG: Cell motility CD630_02350 - fliS1 Type: Gene Product:Flagellar protein FliS1 \| Pathway: \| COG: Cell motility CD630_06540 - Type: Gene Product:ABC-type transport system, permease protein \| Pathway: \| COG: Function unknown CD630_02270 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_13890 - Type: Gene Product:Putative chloromuconate cycloisomerase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_06520 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_25390 - rnz Type: Gene Product:Ribonuclease Z (RNase Z) (tRNase Z) (tRNA 3endonuclease) \| Pathway: \| COG: Function unknown CD630_02280 - fliN Type: Gene Product:Flagellar motor switch protein FliN \| Pathway: \| COG: Cell motility CD630_02380 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_12920 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_02320 - flgL Type: Gene Product:Flagellar hook-associated protein FlgL (or HAP3) \| Pathway: \| COG: Cell motility CD630_02300 - Type: Gene Product:Putative flagellar biosynthesis protein \| Pathway: \| COG: Function unknown CD630_02400 - Type: Gene Product:Glycosyltransferase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_02340 - csrA Type: Gene Product:Carbon storage regulator \| Pathway: \| COG: Signal transduction mechanisms CD630_02360 - fliS2 Type: Gene Product:Flagellar protein FliS2 \| Pathway: \| COG: Cell motility CD630_06530 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_28850 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_25380 - Type: Gene Product:Putative lipoprotein \| Pathway: \| COG: Function unknown CD630_02290 - flgM Type: Gene Product:Anti-sigma factor repressor of sigma(D)-dependenttranscription \| Pathway: \| COG: CD630_02390 - fliC Type: Gene Product:Flagellin C \| Pathway: \| COG: Cell motility	0.04	3.9	0.44	Inferelator: 2 Hypergeometric: 1 TF Influences from Inferelator CD630_12990 - Type: Gene Product:Transcriptional regulator, MarR family \| Pathway: \| COG: Transcription CD630_32800 - Type: Gene Product:Sigma-54 dpendent regulator, PTS fructose family \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test CD630_02660 - sigD Type: Gene Product:RNA polymerase sigma-28 factor for flagellaroperon \| Pathway: \| COG: Transcription
Module_216	20 CD630_21490 - Type: Gene Product:Putative vancomycin resistance protein, vanWfamily \| Pathway: \| COG: Defense mechanisms CD630_21480 - Type: Gene Product:Putative serine/threonine protein kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_23980 - Type: Gene Product:Putative 2-thiocytidine tRNA biosynthesis proteinTtcA \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning CD630_06760 - rsiT Type: Gene Product:Anti Sigma factors, ECF family \| Pathway: \| COG: Function unknown CD630_36790 - rnpA Type: Gene Product:Ribonuclease P protein component (RNaseP protein)(RNase P protein) (Protein C5) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00470 - ispD Type: Gene Product:2-C-methyl-D-erythritol 4-phosphatecytidylyltransferase \| Pathway: Isoprenoid biosynthesis \| COG: Lipid transport and metabolism CD630_22121 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_00480 - ispF Type: Gene Product:2-C-methyl-D-erythritol 2,4-cyclodiphosphatesynthase \| Pathway: Isoprenoid biosynthesis \| COG: Lipid transport and metabolism CD630_32550 - rgaR Type: Gene Product:Two-component response regulator VirR-like \| Pathway: \| COG: Signal transduction mechanisms CD630_23970 - Type: Gene Product:Putative exonuclease \| Pathway: \| COG: Replication, recombination and repair CD630_36760 - mnmE Type: Gene Product:tRNA modification GTPase MnmE \| Pathway: \| COG: Function unknown CD630_36800 - rpmH Type: Gene Product:50S ribosomal protein L34 \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_36780 - oxaA1 Type: Gene Product:Sporulation membrane protein SpoIIIJ \| Pathway: \| COG: Intracellular trafficking, secretion, and vesicular transport CD630_36781 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_06770 - sigT Type: Gene Product:Extra-Cytoplasmic Function sigma factors, ECFfamily \| Pathway: \| COG: Transcription CD630_36770 - Type: Gene Product:Putative SpoIIIJ-associated RNA/ssDNA-bindingprotein Jag \| Pathway: \| COG: Function unknown CD630_19970 - Type: Gene Product:Putative proline iminopeptidase (PIP), S33family \| Pathway: \| COG: Function unknown CD630_19980 - Type: Gene Product:Transcriptional regulator, TetR family \| Pathway: \| COG: Transcription CD630_21320 - Type: Gene Product:Putative transcriptional regulator \| Pathway: \| COG: Transcription CD630_36750 - mnmG Type: Gene Product:tRNA uridine 5-carboxymethylaminomethylmodification enzyme MnmG (Glucose-inhibited divisionprotein A) \| Pathway: \| COG: Cell cycle control, cell division, chromosome partitioning	0	`NA`	0.44	Inferelator: 2 Hypergeometric: 0 TF Influences from Inferelator CD630_06480 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_21110 - Type: Gene Product:Transcriptional regulator, DeoR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_126	7 CD630_31850 - Type: Gene Product:Fragment of putative RNA-binding protein (Part2) \| Pathway: \| COG: Function unknown, Function unknown CD630_12840 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_02731 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_06470 - Type: Gene Product:Fragment of putative fic family protein(C-terminal region) \| Pathway: \| COG: Function unknown CD630_18110 - Type: Gene Product:Fragment of putative two-component sensorhistidine kinase (N-terminal region) \| Pathway: \| COG: Signal transduction mechanisms CD630_28240 - Type: Gene Product:Fragment of putative membrane protein (C-terminalregion) \| Pathway: \| COG: Function unknown CD630_12830 - Type: Gene Product:Conserved hypothetical protein, UPF0297 family \| Pathway: \| COG: Function unknown	`NA`	`NA`	0.44	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_30620 - Type: Gene Product:Transcriptional regulator, RpiR family \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_32	23 CD630_10370 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_19740 - hfq Type: Gene Product:Hfq RNA chaperone \| Pathway: \| COG: Signal transduction mechanisms CD630_18650 - Type: Gene Product:Putative DNA recombination protein Tn1549-like,CTn5-Orf24 \| Pathway: \| COG: Function unknown CD630_10400 - addB Type: Gene Product:ATP-dependent nuclease subunit B (ATP-dependenthelicase addB), Superfamily 1 UvrD-family \| Pathway: \| COG: Replication, recombination and repair CD630_10420 - sbcD Type: Gene Product:Nuclease SbcCD subunit D \| Pathway: \| COG: Replication, recombination and repair CD630_10390 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_18670 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf26 \| Pathway: \| COG: Function unknown CD630_19720 - Type: Gene Product:Putative peptidase, M20A family \| Pathway: \| COG: Amino acid transport and metabolism CD630_00190 - Type: Gene Product:Putative glycosyl transferase \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_14620 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_18680 - Type: Gene Product:Putative conjugative transposon proteinTn1549-like, CTn5-Orf27 \| Pathway: \| COG: Function unknown CD630_23930 - Type: Gene Product:Putative glycosyl transferase, family 51 \| Pathway: Cell wall biogenesis \| COG: Cell wall/membrane/envelope biogenesis CD630_26730 - appB Type: Gene Product:ABC-type transport system, oligopeptide-familypermease protein \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_10430 - sbcC Type: Gene Product:Nuclease SbcCD subunit C \| Pathway: \| COG: Replication, recombination and repair CD630_10410 - addA Type: Gene Product:ATP-dependent nuclease subunit A (ATP-dependenthelicase addA) \| Pathway: \| COG: Replication, recombination and repair CD630_10380 - Type: Gene Product:Putative helicase, superfamily 1, UvrD-family \| Pathway: \| COG: Replication, recombination and repair CD630_18660 - Type: Gene Product:Putative conjugative transposon proteintn1549-like, CTn5-Orf25 \| Pathway: \| COG: Function unknown CD630_18640 - Type: Gene Product:Transcriptional regulator, HTH-type Tn1549-like,CTn5-Orf23 \| Pathway: \| COG: Transcription CD630_14610 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_19420 - trmB Type: Gene Product:tRNA (guanine-N(7)-)-methyltransferase(tRNA(m7G46)-methyltransferase) \| Pathway: tRNA modification \| COG: Energy production and conversion CD630_23940 - polC Type: Gene Product:DNA polymerase III, epsilon subunit \| Pathway: \| COG: Replication, recombination and repair CD630_23920 - Type: Gene Product:Putative tRNA-binding protein \| Pathway: \| COG: Function unknown CD630_14680 - Type: Gene Product:Putative iron-sulfur protein \| Pathway: \| COG: Energy production and conversion	0.05	`NA`	0.45	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_18100 - Type: Gene Product:Transcriptional regulator, beta-lactamsrepressor \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_64	23 CD630_30460 - murQ Type: Gene Product:N-acetylmuramic acid 6-phosphate etherase \| Pathway: Amino-sugar metabolism \| COG: Carbohydrate transport and metabolism CD630_30480 - Type: Gene Product:PTS system, lactose/cellobiose-family IICmembrane component \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_30960 - bglA Type: Gene Product:6-phospho-beta-glucosidase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_30970 - bglF Type: Gene Product:PTS system, beta-glucoside-specific IIABCcomponent \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_33510 - clpP2 Type: Gene Product:ATP-dependent Clp protease proteolytic subunit 2(Endopeptidase Clp 2) \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_24290 - Type: Gene Product:Putative flavodoxin/ferredoxin oxidoreductasealpha subunit \| Pathway: \| COG: Energy production and conversion CD630_33530 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_24250 - ptb Type: Gene Product:Phosphate butyryltransferase(Phosphotransbutyrylase) \| Pathway: \| COG: Energy production and conversion CD630_24260 - buk1 Type: Gene Product:Butyrate kinase 1 (BK 1) (Branched-chaincarboxylic acid kinase 1) \| Pathway: \| COG: Energy production and conversion CD630_24270 - Type: Gene Product:Putative flavodoxin/ferredoxin oxidoreductasegamma subunit \| Pathway: \| COG: Energy production and conversion CD630_30470 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_24230 - Type: Gene Product:Transporter, Major Facilitator Superfamily (MFS) \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_35890 - carA Type: Gene Product:Carbamoyl-phosphate synthase small chain \| Pathway: Amino-acid biosynthesis \| COG: Nucleotide transport and metabolism CD630_30490 - Type: Gene Product:PTS system, lactose/cellobiose-family IIBsubunit \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_30950 - bglA Type: Gene Product:6-phospho-beta-glucosidase \| Pathway: \| COG: Carbohydrate transport and metabolism CD630_24291 - Type: Gene Product:Putative 4Fe-4S ferredoxin, iron-sulfur bindingdomain protein, delta subunit \| Pathway: \| COG: Energy production and conversion CD630_28180 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding/permease protein \| Pathway: \| COG: Defense mechanisms CD630_33540 - Type: Gene Product:Putative tRNA-binding protein \| Pathway: \| COG: Function unknown CD630_30980 - bglG Type: Gene Product:Transcription antiterminator, PTS operonregulator \| Pathway: \| COG: Transcription CD630_24280 - Type: Gene Product:Putative flavodoxin/ferredoxin oxidoreductasebeta subunit \| Pathway: \| COG: Energy production and conversion CD630_33520 - Type: Gene Product:Transcriptional regulator, AraC family \| Pathway: \| COG: Transcription CD630_24240 - Type: Gene Product:Putative pyridoxal phosphate-dependenttransferase \| Pathway: \| COG: Transcription CD630_28170 - Type: Gene Product:ABC-type transport system, multidrug-familyATP-binding/permease protein \| Pathway: \| COG: Defense mechanisms	0.26	0.02	0.45	Inferelator: 0 Hypergeometric: 0 TF Influences from Inferelator `No TF influences from Inferelator` TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_237	20 CD630_34900 - spoIIE Type: Gene Product:Phosphoprotein phosphatase \| Pathway: \| COG: Signal transduction mechanisms CD630_34910 - Type: Gene Product:Putative exopolyphosphatase \| Pathway: \| COG: Nucleotide transport and metabolism, Inorganic ion transport and metabolism CD630_34990 - spoVT Type: Gene Product:Stage V sporulation protein T \| Pathway: \| COG: Transcription CD630_22960 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Transcription CD630_00180 - recR Type: Gene Product:DNA repair and recombination protein \| Pathway: \| COG: Replication, recombination and repair CD630_35010 - mfd Type: Gene Product:Transcription-repair coupling factor (TRCFATP-dependent helicase mfd) \| Pathway: \| COG: Replication, recombination and repair CD630_00170 - Type: Gene Product:DNA binding protein \| Pathway: \| COG: Function unknown CD630_34970 - Type: Gene Product:Bifunctional protein [Includes: Tetrapyrrolemethylase; NTP pyrophosphohydrolase MazG] \| Pathway: \| COG: Function unknown CD630_34930 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_35000 - prsA Type: Gene Product:Peptidylprolyl isomerase PrsA-like \| Pathway: \| COG: Posttranslational modification, protein turnover, chaperones CD630_26110 - mtnN Type: Gene Product:MTA/SAH nucleosidase (5'-methylthioadenosinenucleosidase) (S-adenosylhomocysteine nucleosidase) \| Pathway: Amino-acid biosynthesis \| COG: Nucleotide transport and metabolism CD630_35020 - pth Type: Gene Product:Peptidyl-tRNA hydrolase (PTH) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_00160 - dnaX Type: Gene Product:DNA polymerase III subunits gamma and tau \| Pathway: \| COG: Replication, recombination and repair CD630_34960 - hbs Type: Gene Product:DNA-binding protein, non-specific \| Pathway: \| COG: Replication, recombination and repair CD630_34980 - spoVB Type: Gene Product:Stage V sporulation protein B \| Pathway: \| COG: Cell wall/membrane/envelope biogenesis CD630_22970 - Type: Gene Product:Putative phage-related regulatory protein \| Pathway: \| COG: Transcription CD630_26100 - trpS Type: Gene Product:Tryptophanyl-tRNA synthetase (Tryptophan--tRNAligase) (TrpRS) \| Pathway: \| COG: Translation, ribosomal structure and biogenesis CD630_34940 - Type: Gene Product:Putative spore protein \| Pathway: \| COG: Function unknown CD630_34920 - Type: Gene Product:Septum formation initiation protein \| Pathway: \| COG: CD630_34950 - Type: Gene Product:Putative RNA-binding S4 domain-containingprotein \| Pathway: \| COG: Translation, ribosomal structure and biogenesis	0.05	`NA`	0.45	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_34990 - spoVT Type: Gene Product:Stage V sporulation protein T \| Pathway: \| COG: Transcription TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_205	7 CD630_06750 - Type: Gene Product:Putative acetyltransferase \| Pathway: \| COG: Function unknown CD630_13750 - Type: Gene Product:Putative phage protein \| Pathway: \| COG: CD630_23011 - Type: Gene Product:Fragment of putative phage protein (C-terminalregion) \| Pathway: \| COG: CD630_12382 - Type: Gene Product:Fragment of conserved hypothetical protein(C-terminal region) \| Pathway: \| COG: CD630_13830 - Type: Gene Product:Transcriptional regulator, GntR family \| Pathway: \| COG: Transcription CD630_31001 - Type: Gene Product:Fragment of artefact \| Pathway: \| COG: CD630_33721 - Type: Gene Product:Putative conjugative transposon proteinTn916-like, CTn7-Orf5 \| Pathway: \| COG:	`NA`	`NA`	0.45	Inferelator: 0 Hypergeometric: 0 TF Influences from Inferelator `No TF influences from Inferelator` TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`
Module_83	15 CD630_05830 - Type: Gene Product:Putative diguanylate kinase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_25340 - Type: Gene Product:ABC-type transport system, ATP-binding protein \| Pathway: \| COG: Defense mechanisms CD630_25350 - Type: Gene Product:Two-component sensor histidine kinase \| Pathway: \| COG: Signal transduction mechanisms CD630_32550 - rgaR Type: Gene Product:Two-component response regulator VirR-like \| Pathway: \| COG: Signal transduction mechanisms CD630_20640 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: CD630_28870 - Type: Gene Product:Putative diguanylate kinase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_03410 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_05840 - Type: Gene Product:Putative diguanylate kinase signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_08390 - Type: Gene Product:Putative membrane protein \| Pathway: \| COG: Function unknown CD630_36250 - Type: Gene Product:Putative signaling protein \| Pathway: \| COG: Signal transduction mechanisms CD630_25330 - Type: Gene Product:ABC-type transport system, permease \| Pathway: \| COG: Defense mechanisms CD630_21020 - Type: Gene Product:Putative Na(+)/H(+) antiporter \| Pathway: \| COG: Inorganic ion transport and metabolism CD630_29280 - Type: Gene Product:Conserved hypothetical protein \| Pathway: \| COG: Function unknown CD630_08380 - Type: Gene Product:Putative DNA-binding protein \| Pathway: \| COG: CD630_25360 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms	0	`NA`	0.45	Inferelator: 1 Hypergeometric: 0 TF Influences from Inferelator CD630_30540 - Type: Gene Product:Two-component response regulator \| Pathway: \| COG: Signal transduction mechanisms TF Influences from Hypergeometric Test `No TF Influences from the hypergeometric test`