Module 502 Residual: 0.52

Title Bicluster Model Residual Score
bicluster_0502 v02 0.52 -25.82
Displaying 1 - 20 of 20
Rv2378c L-lysine 6-monooxygenase MbtG (EC 1.14.13.59)

Details for Rv2378c - L-lysine 6-monooxygenase MbtG (EC 1.14.13.59)

GO Terms: GO:0040007

PATRIC Pathways: Lysine degradation

Essentiality: Griffin Essential: 0.68 | In vitro Essential: 0.19 | In vivo Essential: NA

Go to Gene Page: Rv2378c

Tuberculist Genomic Region

Rv2379c Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv2379c - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0005618, GO:0005829, GO:0005886

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2379c

Tuberculist Genomic Region

Rv2380c Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv2380c - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0000036, GO:0005829, GO:0005886, GO:0031177

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.01 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2380c

Tuberculist Genomic Region

Rv2381c Polyketide synthetase MbtD

Details for Rv2381c - Polyketide synthetase MbtD

GO Terms: GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2381c

Tuberculist Genomic Region

Rv2382c Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)

Details for Rv2382c - Malonyl CoA-acyl carrier protein transacylase (EC 2.3.1.39)

GO Terms: GO:0004314, GO:0040007

PATRIC Pathways: Fatty acid biosynthesis

Essentiality: Griffin Essential: 0.42 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv2382c

Tuberculist Genomic Region

Rv2383c Phenyloxazoline synthase MbtB (EC 6.3.2.-)

Details for Rv2383c - Phenyloxazoline synthase MbtB (EC 6.3.2.-)

GO Terms: GO:0000036, GO:0005886, GO:0009405, GO:0010106, GO:0019290, GO:0031177, GO:0052572

PATRIC Pathways: Tryptophan metabolism, Biosynthesis of siderophore group nonribosomal peptides

Essentiality: Griffin Essential: 0.96 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2383c

Tuberculist Genomic Region

Rv2384 Bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase MbtA

Details for Rv2384 - Bifunctional salicyl-AMP ligase/salicyl-S-arcp synthetase MbtA

GO Terms: GO:0008668, GO:0008668, GO:0010106, GO:0016881, GO:0019290

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.49 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv2384

Tuberculist Genomic Region

Rv2386c isochorismate synthase MbtI

Details for Rv2386c - isochorismate synthase MbtI

GO Terms: GO:0004049, GO:0000287, GO:0004106, GO:0005886, GO:0008909, GO:0009697, GO:0010106, GO:0019290, GO:0040007, GO:0043904, GO:0052572

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.15 | In vivo Essential: NA

Go to Gene Page: Rv2386c

Tuberculist Genomic Region

Rv0450c Transmembrane transport protein MmpL4

Details for Rv0450c - Transmembrane transport protein MmpL4

GO Terms: GO:0005576, GO:0005618, GO:0005886, GO:0040007, GO:0044119

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.08 | In vivo Essential: NA

Go to Gene Page: Rv0450c

Tuberculist Genomic Region

Rv1342c CONSERVED MEMBRANE PROTEIN

Details for Rv1342c - CONSERVED MEMBRANE PROTEIN

GO Terms: GO:0005887, GO:0040007

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.08 | In vitro Essential: 0.18 | In vivo Essential: NA

Go to Gene Page: Rv1342c

Tuberculist Genomic Region

Rv1343c Lipoprotein LprD

Details for Rv1343c - Lipoprotein LprD

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1343c

Tuberculist Genomic Region

Rv1344 Acyl carrier protein MbtL

Details for Rv1344 - Acyl carrier protein MbtL

GO Terms: GO:0000036, GO:0005515

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.92 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1344

Tuberculist Genomic Region

Rv1345 Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

Details for Rv1345 - Long-chain-fatty-acid--CoA ligase (EC 6.2.1.3)

GO Terms: GO:0005524, GO:0008922, GO:0044119

PATRIC Pathways: Fatty acid metabolism

Essentiality: Griffin Essential: 0.94 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1345

Tuberculist Genomic Region

Rv1346 Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)

Details for Rv1346 - Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)

GO Terms: GO:0004466, GO:0016627

PATRIC Pathways: Valine, leucine and isoleucine degradation

Essentiality: Griffin Essential: 0.61 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1346

Tuberculist Genomic Region

Rv1347c Lysine N-acyltransferase mbtK (EC 2.3.1.-) (N-acyltransferase mbtK) (Mycobactin synthetase protein K)
Rv1348 ABC transporter ATP-binding protein

Details for Rv1348 - ABC transporter ATP-binding protein

GO Terms: GO:0005886, GO:0009405, GO:0010106, GO:0015891, GO:0040007, GO:0042927, GO:0052099, GO:0055072, GO:0075139

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.06 | In vivo Essential: NA

Go to Gene Page: Rv1348

Tuberculist Genomic Region

Rv1349 ABC transporter ATP-binding protein

Details for Rv1349 - ABC transporter ATP-binding protein

GO Terms: GO:0005829, GO:0005886, GO:0009405, GO:0010106, GO:0015891, GO:0040007, GO:0042927, GO:0052099, GO:0055072, GO:0075139

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.00 | In vitro Essential: 0.04 | In vivo Essential: NA

Go to Gene Page: Rv1349

Tuberculist Genomic Region

Rv1845c Peptidase M48, Ste24p precursor

Details for Rv1845c - Peptidase M48, Ste24p precursor

GO Terms: GO:0005576, GO:0005886

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.02 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1845c

Tuberculist Genomic Region

Rv1846c Transcriptional regulator, BlaI family

Details for Rv1846c - Transcriptional regulator, BlaI family

GO Terms: GO:0003677, GO:0042803, GO:0006355, GO:0046677

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1846c

Tuberculist Genomic Region

Rv1847 Putative esterase

Details for Rv1847 - Putative esterase

GO Terms: NA

PATRIC Pathways: Not assigned

Essentiality: Griffin Essential: 0.78 | In vitro Essential: NA | In vivo Essential: NA

Go to Gene Page: Rv1847

Tuberculist Genomic Region

Displaying 1 - 1 of 1
Motif 1 Motif 2
e-value: 2e-16 e-value: 1.2
Displaying 1 - 1 of 1
Module GO Term Enrichment Descriptions
No enrichment
Displaying 1 - 41 of 41
GO:0040007 |

growth

GO:0005618 |

cell wall

GO:0005829 |

cytosol

GO:0005886 |

plasma membrane

GO:0000036 |

ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process

GO:0031177 |

phosphopantetheine binding

GO:0004314 |

[acyl-carrier-protein] S-malonyltransferase activity

GO:0009405 |

pathogenesis

GO:0010106 |

cellular response to iron ion starvation

GO:0019290 |

siderophore biosynthetic process

GO:0052572 |

response to host immune response

GO:0008668 |

(2,3-dihydroxybenzoyl)adenylate synthase activity

GO:0016881 |

acid-amino acid ligase activity

GO:0004049 |

anthranilate synthase activity

GO:0000287 |

magnesium ion binding

GO:0004106 |

chorismate mutase activity

GO:0008909 |

isochorismate synthase activity

GO:0009697 |

salicylic acid biosynthetic process

GO:0043904 |

isochorismate pyruvate lyase activity

GO:0005576 |

extracellular region

GO:0044119 |

growth of symbiont in host cell

GO:0005887 |

integral to plasma membrane

GO:0005515 |

protein binding

GO:0005524 |

ATP binding

GO:0008922 |

long-chain fatty acid [acyl-carrier-protein] ligase activity

GO:0004466 |

long-chain-acyl-CoA dehydrogenase activity

GO:0016627 |

oxidoreductase activity, acting on the CH-CH group of donors

GO:0008415 |

NA

GO:0016291 |

NA

GO:0016410 |

N-acyltransferase activity

GO:0034069 |

aminoglycoside N-acetyltransferase activity

GO:0015891 |

siderophore transport

GO:0042927 |

siderophore transporter activity

GO:0052099 |

acquisition by symbiont of nutrients from host via siderophores

GO:0055072 |

iron ion homeostasis

GO:0075139 |

response to host iron concentration

GO:0003677 |

DNA binding

GO:0042803 |

protein homodimerization activity

GO:0006355 |

regulation of transcription, DNA-dependent

GO:0046677 |

response to antibiotic